Clinical trials: Neuropathology
CNS Tumor, Neuropathology
Artificial Intelligence Neuropathologist
CNS tumor requires biopsy for pathological diagnosis, which is known as the "golden standard". We would like to achieve automated classification of brain tumors based on deep learning in digital histopathology images and…
- Trial name
- NCT05300113
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Huashan Hospital
Multiple Sclerosis, Parkinson Disease
Early Detection of Selected Neuropathologies in Motor Vehicle Drivers
This study aims to develop accessible methods for the early detection of selected neuropathologies in drivers, focusing on multiple sclerosis and Parkinson's disease.
- Trial name
- NeuroDrive (NCT07360886)
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Olomouc
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Preclinical Imaging Biomarkers of Alzheimer's Disease Neuropathology in Young Adults With Youth-onset Diabetes: a Proof-of-concept Study
The goal of the study is to characterize preclinical Alzheimer's Disease and related dementias (AD/ADRD) neuropathology in a selected group of young adults with youth-onset diabetes, and an age-similar group of young adults…
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetes, Youth Onset
- Trial name
- NCT05350514
- Testing
- PI-2620 tracer
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Epilepsy, Quality of Life
Idiopathic Generalized Epilepsy Cognitive and Emotional Profile
The primary goal of the study is to explore the neurocognitive, emotional-behavioral functioning, and quality of life of adolescents with IGE, identifying key factors that affect their overall well-being.
- Conditions
- Epilepsy, Quality of Life, Neuropathology, Emotional Problem
- Trial name
- NCT06782074
- Testing
- emotional and neuropsychological assessment
- Where
- Italy
- Volunteers
- 96 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Neuropathology
Prospective Study Evaluating the Interest of Long-term Cardiac Recording in Cerebral Infarction
Cerebral infarction (CI) can be linked to atherosclerosis of large vessels, occlusion of small vessels intracerebral (gaps), a cardioembolic disease or other rare causes.
- Trial name
- SPIDERFLASH (NCT02778321)
- Testing
- Uses of SpiderFlash monitor
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Coma, Disorder of Consciousness
Development of a Point of Care System for Automated Coma Prognosis
Electroencephalogram/event-related potentials (EEG/ERP) data will be collected from 50 participants in coma or other disorder of consciousness (DOC; i.e., Unresponsive Wakefulness Syndrome [UWS] or Minimally Conscious State…
- Conditions
- Coma, Disorder of Consciousness, Minimally Conscious State, Vegetative State
- Trial name
- NCT03826407
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- McMaster University
Alzheimer Disease, Dementia
Longitudinal Validation of a Computerized Cognitive Battery (Cognigram) in the Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease
This research project will test two new computerized technologies in the detection of brain changes related to Mild Cognitive Impairment (MCI) and dementia due to Alzheimer's disease. These technologies are: 1.
- Conditions
- Alzheimer Disease, Dementia, Neuropathology, Mild Cognitive Impairment
- Trial name
- NCT03676881
- Testing
- Computerized cognitive battery: Cognigram (CG), The NeuroCatch™ Platform (NCP)
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Bruyère Health Research Institute.
Amyotrophic Lateral Sclerosis
In-situ Cytokines Expression in the CNS in Amyotrophic Lateral Sclerosis (ALS)
The investigators aim at exploring the differential/topographical in-situ expression of cytokines in the central nervous system (CNS) of patients who died with amyotrophic lateral sclerosis (ALS), using archived histopathology…
- Trial name
- NCT02582385
- Testing
- in-situ cytokine expression
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Brugmann University Hospital
Voice Disorders, Spasmodic Dysphonia
Neuropathology of Spasmodic Dysphonia
This study will look for abnormalities in a brain of persons affected with spasmodic dysphonia, a form of movement disorder that involves involuntary "spasms" of the muscles in the vocal folds causing breaks of speech and…
- Conditions
- Voice Disorders, Spasmodic Dysphonia, Healthy, Movement Disorder
- Trial name
- NCT00118586
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)