Clinical trials: Neuromuscular Monitoring
Neuromuscular Blockade, Neuromuscular Monitoring
Development and Validation of an Android-based Application for Anaesthesia Neuromuscular Monitoring
The present study aims to assess the accuracy of a newly developed Android Smartphone Application in measuring the degree of Neuromuscular block in the perioperative period.
- Trial name
- NCT03605225
- Testing
- mobile cellphone application test
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Universitair Ziekenhuis Brussel
Muscular Dystrophy, Duchenne
Double Push Acoustic Radiation Force (DP ARF) Ultrasound for Monitoring Degeneration in Duchenne Muscular Dystrophy
This is a pilot clinical trial to assess the ability of a new ultrasound-based imaging method, Double-Push Acoustic Radiation Force (DP ARF) ultrasound, to monitor the progression of Duchenne muscular dystrophy.
- Trial name
- NCT01506518
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Motor Neurone Disease, Respiratory Insufficiency
Home Versus Hospital Based NIV Care in MND
Non-invasive ventilation (NIV) is commonly offered to people with Motor Neurone Disease (MND) who have breathing difficulties. It improves their quality of life and can prolong life by 6 months or more.
- Trial name
- HoHoNIV (NCT06844370)
- Testing
- Non-invasive ventilation
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Neuromuscular Blockade Monitoring
Estimation of Neuromuscular Recovery - a Validation Study
Neuromuscular blocking (NMB) agents are used in the vast majority of surgical interventions. Although pharmacokinetic and pharmacodynamic data are available, there is a large interindividual variability in the time needed for…
- Trial name
- NCT05716282
- Testing
- Accuracy of neuromuscular recovery estimation
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital
ICU Acquired Weakness
Safety and Efficacy of the MyokinE100 (CL-EMS Alpha) Device in Inducing Visible Muscle Contraction in Healthy Volunteers
Every patient admitted to the Intensive Care Unit (ICU) is at risk of developing "Intensive Care Unit Acquired Weakness" (ICUAW).
- Trial name
- NCT06023511
- Testing
- Electrical muscle stimulation
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Health Discovery Labs
Amyotrophic Lateral Sclerosis
Validation of Czech Language Versions of Questionnaires for ALS Patients' Functional Status and Biomarker Long-term Follow-up
Questionnaires and scales used to assess the clinical status and quality of life of patients with amyotrophic lateral sclerosis (ALS) are an important tool to monitor the disease progression and current needs of patients.
- Trial name
- NCT06426030
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Masaryk University
Neuromuscular Blockade
Median Versus Ulnar Nerve Quantitative Electromyography Neuromuscular Blockade Monitoring Comparison
Medications used to relax the muscles are used during surgery. The amount of muscle relaxation can monitored with devices that stimulate a specific nerve and evaluate the muscle response.
- Trial name
- NCT06553131
- Testing
- Neuromuscular Transmission Monitoring
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Loma Linda University
Neuromuscular Blockade
Improving Neuromuscular Monitoring and Reducing Residual Neuromuscular Blockade Via E-learning
To assess the impact of an e-learning course in neuromuscular monitoring on the frequency of application of objective neuromuscular monitoring for assessment of depth of neuromuscular blockade in general anaesthesia and…
- Trial name
- INVERT (NCT02925143)
- Testing
- E-learning course in neuromuscular monitoring
- Where
- Denmark
- Volunteers
- 6,525 people
- Sponsor
- Herlev Hospital
Anesthesia, Anesthesia Recovery Period
Minimum Current for Train-of-four Monitoring
Neuromuscular monitoring during general anesthesia is important to make sure adequate muscle relaxation during operation and adequate recovery of muscle power and spontaneous breathing during emergence from general anesthesia.
- Conditions
- Anesthesia, Anesthesia Recovery Period, Neuromuscular Blockade
- Trial name
- NCT04581720
- Testing
- Train-of-four (TOF)
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Ewha Womans University Mokdong Hospital
Multiple Sclerosis
Smart Monitoring Assessing Spasticity-related Health
This observational study seeks to investigate the underlying of spasticity in patients with multiple sclerosis (MS) by employing multimodal monitoring techniques.
- Trial name
- SMASH (NCT06937723)
- Testing
- Device: Smartwatch (Withings Scanwatch)
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Novel MRI Biomarkers for Monitoring Disease Progression in ALS
Routine MRI is normal in motor neuron diseases such as ALS. However, advanced MRI techniques can provide an objective measure of degeneration (a "biomarker") by examining brain structure, wiring, chemistry, and function.
- Trial name
- NCT03362658
- Where
- 7 sites in United States, Canada
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Hemifacial Spasm, Microvascular Decompression
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD. However, there have been no evidence of which degree of partial neuromuscular blockade should be performed during LSR…
- Conditions
- Hemifacial Spasm, Microvascular Decompression, Neuromuscular Blockade
- Trial name
- NCT01613781
- Testing
- TOF count-guided partial NMB, T1/Tc guided partial NMB
- Where
- South Korea
- Volunteers
- 61 people
- Sponsor
- Samsung Medical Center
Neuromuscular Blockade
Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor
A quantitative neuromuscular monitoring device is desirable to titrate the depth of neuromuscular block (NMB) during a procedure, and to prevent residual effects after removal of the endotracheal tube.
- Trial name
- NCT05632107
- Testing
- TOF-Watch®；DELSYS® Wireless surface EMG
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Huazhong University of Science and Technology
Anesthesia,General, Neuromuscular Blockade
MONITORING NEUROMUSCULAR BLOCK IN PAEDIATRIC ANAESTHESIA
To date there is still little scientific evidence regarding neuromuscular block monitoring in pediatric anesthesia and indications for safe reversal.
- Conditions
- Anesthesia,General, Neuromuscular Blockade, Tracheal Intubation
- Trial name
- MOTOR (NCT06331611)
- Testing
- TOF monitoring
- Volunteers
- 200 people
- Sponsor
- Istituto Giannina Gaslini
Neuromuscular Blockade
The Precision and Arm-to-Arm Variation of Mechanomyography and Acceleromyography for Monitoring of Neuromuscular Block
The purpose of the study is the examine the precision of acceleromyography and mechanomyography during recovery from a neuromuscular blocking agent and to examine whether there is any difference in monitoring block at the…
- Trial name
- NCT00472121
- Testing
- TOF-Watch SX (neuromuscular monitor)
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sugammadex
Quantitative Neuromuscular Monitoring and Gastric Bypass Surgery
This is a single site, prospective, non-blinded, non-randomized, before/after study. This study is designed to evaluate the impact of monitoring and reversal guidelines for neuromuscular blocking drugs on the post-operative…
- Trial name
- NCT05886218
- Testing
- Quantitative Neuromuscular Function Monitoring
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- University of California, Davis
ARDS, TTM
TwichView-guided Atricurium Dose Adjustment Trial
The goal of this clinical trial is to learn if using a monitor that measures muscle response can lower the amount of muscle relaxant medicine needed in adults who are treated in an intensive care unit (ICU) and need a continuous…
- Conditions
- ARDS, TTM, ECMO, Neuromuscular Blockade Monitoring
- Trial name
- NCT07807046
- Testing
- EMG-based quantitative TOF-guided atracurium titration
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Fu Jen Catholic University Hospital
Type 1 Diabetes
The Summer Camp Study 2: Blood Glucose Control With a Bi-Hormonal Endocrine Pancreas
This study will test the hypothesis that a wearable automated bionic pancreas system that automatically delivers both insulin and glucagon can improve glycemic control vs.
- Trial name
- NCT02105324
- Testing
- Bionic Pancreas, Usual Care
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Massachusetts General Hospital
Neuromuscular Blockade
Interest of the Automated Management of Deep Neuromuscular Blockade Monitoring (CURATP)
Neuromuscular blockade (NMB) recommendations updated in 2018 by the Société Française d'Anesthésie et Réanimation (SFAR) recommend the use of NMB agents to facilitate surgical procedure during abdominal surgery by laparotomy or…
- Trial name
- CURATP (NCT05784610)
- Testing
- Monitorage by TOF/PTC, Monitorage by ATP
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Poitiers University Hospital
Linezolid, Tuberculosis Multi Drug Resistant Active
Linezolid Tolerance During the BPaL Regimen With Dosage Personalization Based on Therapeutic Drug Monitoring (TDM) During Multidrug-Resistant Tuberculosis Treatment
Multidrug-resistant tuberculosis (MDR-TB) poses a significant challenge to global public health. Globally, the World Health Organization (WHO) estimates the number at 400,000 patients with MDR-TB for 2023.
- Conditions
- Linezolid, Tuberculosis Multi Drug Resistant Active, Therapeutic Drug Monitoring (TDM)
- Trial name
- PLOT-TB (NCT07477119)
- Testing
- Linezolid dose personalization based on TDM
- Where
- Guinea
- Volunteers
- 150 people
- Sponsor
- Marco Schiuma