Clinical trials: Neuromuscular Monitoring
Neuromuscular Blockade, Intraoperative Monitoring
Gentle Skin Abrasion and EMG-Based Neuromuscular Blockade Monitoring
This study will evaluate whether gentle skin abrasion improves electromyographic signal quality during neuromuscular blockade monitoring in adult surgical patients.
- Conditions
- Neuromuscular Blockade, Intraoperative Monitoring, Skin Preparation, Electromyography
- Trial name
- NCT07759206
- Testing
- Gentle Skin Abrasion Before EMG-Based Neuromuscular Blockade Monitoring
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Minnesota
Neuromuscular Block, Orthopedic Disorder of Spine
Neuromuscular Blockade for Optimising Surgical Conditions During Spinal Surgery
In the present study, the investigators compare intermediate and deep NMB i.e. the two extreme regimes of muscle paralysis (neuromuscular block; NMB), (I) patients receiving intermediate muscle paralysis (''control, conventional…
- Conditions
- Neuromuscular Block, Orthopedic Disorder of Spine, Muscle Weakness
- Trial name
- NCT02778945
- Testing
- Rocuronium 0.9 mg/kg, Rocuronium 0.6 mg/kg
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- The Catholic University of Korea
Neuromuscular Blockade, Neuromuscular Blockade Monitoring
Muscle and Fat Mass in Preoperative Computed Tomography and a Neuromuscular Blocking Agent Dose
Deep neuromuscular blockade has benefits in various surgical procedures and reduces postoperative pain. While neuromuscular blockade dosages are often based on the patient's actual body weight, body composition can vary…
- Trial name
- NCT07478120
- Testing
- Neuromuscular block
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Seoul National University Bundang Hospital
Neuromuscular Diseases, Scoliosis
Evaluation of the Feasibility of Remote Monitoring of Mechanical In-exsufflation Devices in Paralytic and Neuromuscular Patients Treated at Home.
The implementation of an mechanical in-exsufflator device (MI-E) requires specific expertise because it is a complex device that requires fine-tuning of the settings according to different clinical situations to optimize its…
- Trial name
- TELE-INEX (NCT05723289)
- Testing
- MI-E Telemonitoring
- Where
- France
- Volunteers
- 10 people
- Sponsor
- KerNel Biomedical
Fibromyalgia
Mindfulness-Based Stress Reduction Program as an Intervention in Patients With Fibromyalgia
Fibromyalgia is a clinical syndrome with chronic pain, fatigue, and sleep disorders being the main symptoms. There is no commonly accepted efficacious treatment modality.
- Trial name
- NCT00106275
- Testing
- Mindfulness Based Stress Reduction
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University Hospital Freiburg
Surgery
An Evaluation of the Neuromuscular Junction in Neonates Using the TetraGraph
The goal of this study is to use electromyography-based train-of-four monitoring (TetraGraph™ Neuromuscular Transmission Monitor) as a means of evaluating differences in neuromuscular transmission between infants ≤ 3 months of…
- Trial name
- NCT07133412
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Joseph D. Tobias
Neuromuscular Blockade, Anesthesia, General
Comparison of the Performances of the cTOFR and the mTOFR During Reversal of Deep Neuromuscular Blockade With Sugammadex
It is known that deep neuromuscular block improves surgical conditions, especially during laparoscopic abdominal surgery. Based on this, in the Perioperative Neuromuscular Blockade Management guide published by the ESAIC…
- Trial name
- NCT06220136
- Testing
- TOFscan monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara University
Multiple Sclerosis, Foot Drop
Walking With FES or AFO in People With MS With Foot Drop
This investigation consists of two parallel groups of participants who will follow the same protocol. The aim of the study is to investigate the effects of using Functional Electrical Stimulation/Ankle Foot Orthosis (AFO) or…
- Trial name
- NCT01977287
- Testing
- Functional Electrical Stimulation, Ankle Foot Orthosis
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Queen Margaret University
Peripheral Nerve Injuries, Thoracic Surgery
Somatosensory Evoked Potential (SSEP) Monitoring for Detection of Intraoperative Positional Neuropraxia
PNI (Peripheral Nerve Injury) occurs in 5-15% of patients in cardiac surgery. So far, the mechanism of injury has never been researched.
- Trial name
- NCT03422107
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Western University, Canada
Neurofibromatosis 1, Neurofibroma, Plexiform
Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1(NF1) on Clinical Treatment Trials
Background: Neurofibromatosis type 1 (NF1) is a genetic disorder. It has a broad variety of effects on the body. Up to half of people with NF1 get plexiform neurofibromas (PNs). These are benign tumors.
- Trial name
- NCT03531814
- Testing
- Medication Event Monitoring System (MEMS^TM), Questionnaires
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Cancer Institute (NCI)
Respiratory Failure, Neuromuscular Disease
Ventilator Monitoring in Early Exacerbation Detection
The aim of this study is to determine whether respiratory disease exacerbations (a sudden worsening of symptoms) can be predicted by variables that are monitored by non-invasive ventilators (small machines that assist breathing)…
- Conditions
- Respiratory Failure, Neuromuscular Disease, Chest Wall Disorder, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT01644162
- Testing
- iVAPS ventilation
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- ResMed
Anesthesia, Neuromuscular Blockade
International Focus Group Discussion on Neuromuscular Monitoring.
Focus-Group based discussion designed to gain more in-depth information on factors that could lead to an increase in the adoption of neuromuscular monitoring taking into account different country-specific contexts.
- Conditions
- Anesthesia, Neuromuscular Blockade, Neuromuscular Block, Residual, Perioperative/Postoperative Complications
- Trial name
- NCT06945341
- Testing
- Focus-Group discussion
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Patients Undergoing General Anesthesia
A Comparative Study of the Next-Generation TetraGraph® and Mechanomyography Neuromuscular Monitors in Clinical Settings
Background: Neuromuscular monitoring plays a critical role in reducing postoperative residual neuromuscular blockade (PRNB), a significant risk factor for respiratory complications.
- Trial name
- MMG vs EMG NG (NCT07750405)
- Testing
- Mechanomiograph (MMG), Electromiograph (EMG)
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- University of Debrecen
Neuromuscular Blockade Monitoring
Monitoring of Neuromuscular Blockade in the Intensive Care Unit: a Reliability Study
The objective of this clinical trial is to evaluate the reliability of neuromuscular blockade monitoring in adult intensive care patients depending on the clinical context.
- Trial name
- CURAREA (NCT07741851)
- Testing
- neuromuscular blockade monitoring
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Intercommunal Aix-Pertuis
Pain, Chronic, Lumbar Radiculopathy
Study on the Use of Intraoperative Neurophysiological Monitoring in Spinal Cord Stimulator Trials
This is an observational pilot study. The spinal cord stimulator (SCS) procedure and neuromonitoring device is not under investigation. Neuromonitoring is typically performed on this patient population receiving SCS trials here.
- Conditions
- Pain, Chronic, Lumbar Radiculopathy, SCS
- Trial name
- SCS-Monitor (NCT05540756)
- Where
- United States
- Sponsor
- University of Chicago
Neuromuscular Monitoring
Comparison of Two Neuromuscular Monitors
Different neuromuscular monitors may be available in the same care structure. Two different monitors are available in the investigators' institution in the operative room and the recovery room.
- Trial name
- NMT-STIMPOD (NCT02350062)
- Volunteers
- 17 people
- Sponsor
- University Hospital, Caen
Preoperative Anxiety, Intraoperative Hemodynamics and Drug Consumption
Evaluation of the Effects of Preoperative Anxiety in Patients Undergoing Total Intravenous Anesthesia (TIVA)
Most patients have varying degrees of anxiety and fear before surgery. We believe that preopertive anxiety levels have an effect on intraoperative hemodynamics and recovery and affect intraoperative drug consumption.
- Trial name
- NCT04690764
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Curarisation, Neuromuscular Monitoring
Comparison of Two Neuromuscular Transmission Monitors Based on Acceleromyography: TOF-Watch SX® and TOFScan®
The purpose is to evaluate the reproducibility of neuromuscular monitoring data of recovery from neuromuscular blockade, obtained with TOFScan® and TOF-Watch SX®, in adult and pediatric population.
- Trial name
- TOFScan (NCT02880787)
- Testing
- Rocuronium, Neuromuscular monitoring with TOFScan® and TOF-Watch SX®
- Where
- France
- Volunteers
- 142 people
- Sponsor
- Central Hospital, Nancy, France
ALS (Amyotrophic Lateral Sclerosis)
Home-based Remote Digital Monitoring to Assess ALS Progression (Track ALS)
The purpose of this study is to study use of advance Digital Health Technologies (DHT) and its validity as measures for assessing progression in Amyotrophic Lateral Sclerosis (ALS) patients.
- Trial name
- NCT05276349
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Availability of the Different Types of Anesthesia Neuromuscular Monitoring Devices Throughout European Hospitals, Health Care Utilization
European Neuromuscular Monitoring Survey
This survey aims to better define the availability of the different types of anesthesia neuromuscular monitoring devices throughout European hospitals.
- Conditions
- Availability of the Different Types of Anesthesia Neuromuscular Monitoring Devices Throughout European Hospitals, Health Care Utilization, Medical Device Availability, Medical Staff Availability
- Trial name
- NCT04517578
- Testing
- Survey
- Where
- Belgium
- Volunteers
- 692 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel