Clinical trials: Neuromuscular Diseases
Sensorimotor Gait Disorder, Neurologic Ambulation Disorder
Clinical Study of the L300 Versus Ankle-foot Orthosis (AFO) on Post-Stroke Subjects With Foot Drop
The objective of this study is to determine the effectiveness of the NESS L300 (L300) in improving gait parameters, function, and quality of life among stroke subjects (greater than or equal to 3 months post stroke)with drop foot.
- Conditions
- Sensorimotor Gait Disorder, Neurologic Ambulation Disorder, Gait, Drop Foot, Poststroke Hemiparesis
- Trial name
- L300 (NCT01138995)
- Testing
- Ness L300, Ankle-foot orthosis
- Where
- 11 sites in United States
- Volunteers
- 197 people
- Sponsor
- Bioness Inc
Stroke, Motor Disorders
Functional Proprioceptive Stimulation of the Upper Limbs in Stroke Patients
Parallel-group, single-blinded controlled clinical trial. The study involved stroke patients (no more than 3 points on a scale Rankin) dived of the control group and experimental group.
- Conditions
- Stroke, Motor Disorders, Upper Extremity Paresis, Muscle Weakness
- Trial name
- NCT06143475
- Testing
- FPS group, Conventional therapy group
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Carpal Tunnel Syndrome
Oral Gabapentin and Median Nerve Mobilization in the Treatment of Carpal Tunnel Syndrome
The present randomized clinical trial will perform a comparison of the pain reduction effects produced by the application of a non invasive and non pharmacological median nerve neural mobilization (physiotherapy treatment), to…
- Trial name
- NCT04285281
- Testing
- Gabapentin oral capsules, Median nerve neural mobilization
- Where
- Venezuela
- Volunteers
- 126 people
- Sponsor
- Universidad Europea de Madrid
Carpal Tunnel Syndrome
Phonophoresis, Low-Level Laser Therapy and Exercise in the Treatment of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral nerve compression syndrome. There is insufficient evidence about the efficacy and superiority of conservative treatment methods.
- Trial name
- NCT05213819
- Testing
- Carpal Tunnel Syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Low Back Pain, Radiculopathy
Effectiveness of Ozone Therapy Versus Pulsed Radiofrequency in Low Back Pain With Radiculopathy
Treatment selection for refractory radicular low back pain is frequently made in the absence of direct comparative evidence between competing minimally invasive options.
- Trial name
- NCT07773428
- Testing
- Intradiscal ozone therapy, Pulsed radiofrequency
- Where
- Oman
- Volunteers
- 69 people
- Sponsor
- Zagazig University
Arteriopathy
Effect of a Neuromuscular Electrical Stimulation Program on Walking Capacity in Peripheral Artery Disease Patients
Lower extremity peripheral arterial disease (LEPAD) is a highly prevalent chronic disease. Cardiovascular mortality of LEPAD patients at five years ranges between 18 to 30%.
- Trial name
- ELECTROPAD (NCT03795103)
- Testing
- neuromuscular electrical stimulator, Walking sessions, Advices
- Where
- 5 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis
Digital Assessment of Speech and Fine Motor Control in ALS
This is a single-session, case-control study that incorporates digital tools for assessing speech and motor function in motor neuron disease.
- Conditions
- Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis, Progressive Muscular Atrophy
- Trial name
- NCT06315673
- Testing
- Digital Speech and Handwriting Assessment
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Hemiplegia
The Relationship Of Ultrasonographic Measurements With Sarcopenia in Stroke
introduction:The aim of this study was to show the relationship of distal femoral cartilage and quadriceps thicknesses with functional status and presence of sarcopenia in ambulatory stroke patients with voluntary movement.
- Trial name
- NCT06254573
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Kayseri City Hospital
Cerebrovascular Accident
A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi®) in Subjects With Post-stroke Upper Limb Spasticity
This is a multicenter, double-blind, randomized, placebo-controlled study designed to compare Botulinum Toxin Type A for Injection (HengLi®) with placebo on the efficacy and safety of treatment in post-stroke subjects with focal…
- Trial name
- NCT02280083
- Testing
- Botulinum Toxin Type A for Injection
- Volunteers
- 180 people
- Sponsor
- Lanzhou Institute of Biological Products Co., Ltd
Sporadic Inclusion Body Myositis
Blood-flow Restricted Exercise in Inclusion Body Myositis
This study evaluates the effects of a low-intensity blood-flow restricted exerciser protocol on patient reported physical function, in patients with sporadic inclusion body myositis.
- Trial name
- NCT02317094
- Testing
- Blood-flow restricted training, Care as usual
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- University of Southern Denmark
Sarcopenia, Liver Cirrhosis
Microbiome and Sarcopenia in Patients With Liver Cirrhosis
Protein-energy malnutrition (PEM) occurs in 65-90% of patients with liver cirrhosis. Severity of malnutrition correlates with progression of liver disease and leads to sarcopenia in 30-70% of cirrhotic patients.
- Trial name
- NCT03080129
- Testing
- Fresubin energy
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Spastic Diplegic Cerebral Palsy
Efficacy and Functional Outcomes of Botulinum Toxin A Injections to Hamstrings in Flexed Knee Gait in Cerebral Palsy
The study proposes to determine if injections of BTX-A to the hamstring muscles result in measurable physiologic changes not observed with normal saline injections in children with spastic diplegic cerebral palsy who walk with a…
- Trial name
- NCT00261131
- Testing
- Botulinum Toxin A
- Volunteers
- 250 people
- Sponsor
- Shriners Hospitals for Children
Multiple Sclerosis, Balance; Distorted
The Effect of Cervical Mobilization on Balance and Spasticity in Multiple Sclerosis Individuals
Taking into consideration the effects of mobilization on muscle tone and balance, it is predicted that this method will have effective results in the treatment of individuals with MS.
- Trial name
- NCT03706131
- Testing
- cervical mobilisation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Fibromyalgia
Effects of Connective Tissue Massage in Patients With Fibromyalgia
Connective tissue massage (CTM), one of the various manual therapy techniques for FMS, produces local mechanical effects on mast cells in the connective tissue with short and long tractions, thereby reducing sympathetic activity…
- Trial name
- NCT06469996
- Testing
- Connective tissue massage, Self myofascial relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Firat University
Piriformis Syndrome
Effects of Reciprocal Inhibition Versus Post Facilitation Muscle Energy Technique Along With Conventional Physical Therapy in Patients With Piriformis Syndrome: a Randomized Controlled Trial
This study is a randomized controlled trial and the purpose of this study is to compare the effects of reciprocal inhibition versus post facilitation muscle energy technique along with conventional physical therapy in patients…
- Trial name
- NCT06534788
- Testing
- Reciprocal Inhibition MET, Post-facilitation MET, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Foundation University Islamabad
Sarcopenia
Effect of Alfacalcidol on Muscle Function in Osteoporosis Patients
This study aims to investigate the potential improvement in muscle function, compared to the placebo group, through the concurrent administration of denosumab and alfacalcidol over a one-year period in postmenopausal women with…
- Trial name
- NCT06272227
- Testing
- alfacalcidol, Denosumab
- Where
- South Korea
- Volunteers
- 340 people
- Sponsor
- Yonsei University
Post-Operative Nausea and Vomiting, Breast Cancer
Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV)
The goal of this clinical research study is to learn if light electrical stimulation to the wrist area during surgery is feasible in women having breast surgery.
- Trial name
- NCT02473042
- Testing
- Electrical Stimulation, Zofran, Dexamethasone
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- M.D. Anderson Cancer Center
Osteoarthritis
STOP OA: A PILOT STUDY (GLA:D Canada) - Education and Targeted, Personalized Exercise for Hip and Knee Osteoarthritis
Osteoarthritis (OA) most often affects the hip and knee joints. The first signs and symptoms of pain, stiffness or swelling are not uncommon in those in their thirties and forties and 10 per cent report symptomatic knee OA by age…
- Trial name
- NCT02693873
- Testing
- GLA:D Canada (education and neuromuscular exercise program)
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- Aileen Davis
Diabetes Mellitus (DM)
Central Sensitization in Painful and Painless Diabetic Peripheral Neuropathy
This research is structured as a cross-sectional observational study. The primary objective is to compare central sensitization across painful and painless phenotypes of diabetic peripheral neuropathy.
- Trial name
- NCT07316322
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Inonu University
Amyloid Cardiomyopathy
Unmasking the Prevalence of AC in an Unselected Echocardiographic Population
This study will investigate the prevalence of echocardiographic red-flags of amyloid cardiomyopathy (AC) in patients undergoing clinically-indicated echocardiography (observational phase) and the prevalence of AC among…
- Trial name
- AC-TIVE (NCT04738266)
- Testing
- Amyloid Cardiomyopathy
- Where
- 16 sites in Italy
- Volunteers
- 381 people
- Sponsor
- University of Trieste
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