Clinical trials: Neuromuscular Control
Carpal Tunnel Syndrome
Effect of Blood Flow Restriction on Pain Perception, Grip Strength and Nerve Conductivity in CTS Patients.
The goal of this clinical trial is to investigate the effect of blood flow restriction (BFR) on pain perception, grip strength and nerve conductivity in patients suffering from carpal tunnel syndrome (CTS).
- Trial name
- NCT06574841
- Testing
- Blood Flow Restriction training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Multidirectional Instability, Hypermobility Spectrum Disorder
Impact of Neuromuscular Control With and Without Electrical Stimulation and Long-term Effect of Kinetic Chain Exercises in Multidirectional Shoulder Instability Patients
Background: Shoulder instability is commonly observed in adolescents and young females, ranging from asymptomatic multidirectional instability (MDI) to symptomatic conditions.
- Conditions
- Multidirectional Instability, Hypermobility Spectrum Disorder, Electrical Stimulation, Neuromuscular Control
- Trial name
- NCT07611006
- Testing
- neuromuscular eletrical stimulation, neuromuscular control training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Fibromyalgia, Irritable Bowel Syndrome
Observational Study of Control Participants for the MAPP Research Network
The Control Study for the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Fatigue Syndrome, Chronic
- Trial name
- MAPP-Control (NCT01098292)
- Where
- 8 sites in United States
- Volunteers
- 615 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cachexia
Study of GTx-024 on Muscle Wasting (Cachexia) Cancer.
The purpose of this study is to assess if Gtx-024 is effective in increasing lean body mass in subjects with muscle wasting related to cancer.
- Trial name
- NCT00467844
- Testing
- GTx-024
- Where
- 52 sites in United States, Canada
- Volunteers
- 159 people
- Sponsor
- GTx
Widspread Chronic Pain, Fibromyalgia
The Effect of Vagus Nerve Stimulation on Pain and Functional Activities in Individuals With Chronic Widespread Pain
The goal of this clinical trial is to examine the effect of vagus nerve stimulation (VNS) on chronic, widespread pain in adults.
- Trial name
- NCT07080749
- Testing
- Vagal nerve stimulation through deep exhalation exercise, Vagal nerve stimulation through ear electrical stimulation, No intervention (observational study)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Georgia
Fibromyalgia, Chronic Widespread Pain
Effects of and Exploring the Processes of Free Movement Dance as a Physical Therapy Intervention for Female Patients Diagnosed With Chronic Widespread Pain (Including Fibromyalgia).
The study has three parts: Part 1: To evaluate, for adult female patients diagnosed with chronic widespread pain (including fibromyalgia), the effects of Free Movement Dance as an add-on intervention after interdisciplinary pain…
- Trial name
- NCT05282758
- Testing
- Free Movement Dance, Modified person-centred progressive resistance exercise
- Where
- Sweden
- Volunteers
- 52 people
- Sponsor
- Göteborg University
Muscle Spasticity
Safety and Preliminary Effectiveness of AV650 in Patients With Spasticity Associated With Multiple Sclerosis
A drug called AV650 (tolperisone HCl) will be given to patients who have spasticity associated with multiple sclerosis. This study has three purposes: 1. To determine whether AV650 is safe for patients with multiple sclerosis; 2.
- Trial name
- NCT00532532
- Testing
- tolperisone HCl
- Where
- 28 sites in Czechia, Germany and 3 more
- Volunteers
- 150 people
- Sponsor
- Avigen
Spasticity, Multiple Sclerosis
Evaluate the Maintenance of Effect After Long-term Treatment With Sativex® in Subjects With Symptoms of Spasticity Due to Multiple Sclerosis
The purpose of this study is to evaluate the maintenance of effect after long-term treatment with Sativex® in subjects with symptoms of spasticity due to Multiple Sclerosis (MS) who have been receiving long-term benefit from…
- Trial name
- NCT00702468
- Testing
- Sativex
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Jazz Pharmaceuticals
Obesity, Sarcopenia
Diet and Exercise Interventions to Increase Muscle Strength and Function
The objective of this study is to test the effects of a healthy diet \& walking (Controls) compared to a healthy diet, walking, and balance/strength exercises (Intervention) on muscle density in two populations: elderly…
- Conditions
- Obesity, Sarcopenia, Metabolic Syndrome X
- Trial name
- NCT02850562
- Testing
- Walking, Walking + Exercise
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Osteoarthritis, Pain Intensity Assessment
A Study to Evaluate 90-Day Safety of Tapentadol(CG5503) Immediate Release (IR) or Oxycodone Immediate Release in Patients With Chronic Pain
The purpose of this study is to evaluate the safety of CG5503 base Immediate Release(IR) 50 mg or 100 mg taken every 4 to 6 hours as needed over the long-term exposure of 90 days in patients who have chronic pain.
- Conditions
- Osteoarthritis, Pain Intensity Assessment, Arthralgia, Sciatica
- Trial name
- NCT00364546
- Testing
- CG 5503;tapentadol
- Volunteers
- 877 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Trismus
Effectiveness of Serratiopeptidase After Mandibular Third Molar Surgery
This randomized controlled trial was conducted to compare the effect of serratiopeptidase versus no intervention on postoperative mouth opening, swelling, and trismus following surgical removal of mesioangular mandibular third…
- Trial name
- NCT07543146
- Testing
- Serratiopeptidase, Standard Postoperative Care
- Where
- Pakistan
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Sharif Medical Research Center
Carpal Tunnel Syndrome, Hand Cyst Ganglion
Effectiveness of Audiovisual Versus Written Postoperative Instructions for Patients Undergoing Minor Hand Procedures
The utility and effectiveness of video-based instructions (VBI) versus standard written instructions was not previously investigated in hand surgery; thus, the objective of this study is to evaluate the effectiveness of…
- Conditions
- Carpal Tunnel Syndrome, Hand Cyst Ganglion, Trigger Finger
- Trial name
- NCT06582550
- Testing
- Minor Hand Procedure
- Volunteers
- 120 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Spastic Hemiplegia
Evaluation of Spasticity, Neuropathic Pain, and Gait Analysis in Stroke Patients Receiving Tolperison Therapy After Botulinum Toxin Injection
Tolperison is an antispastic agent used in the treatment of spasticity. Studies on tolperison are limited, and the literature on its effectiveness against spasticity and neuropathic pain is also limited.
- Trial name
- NCT07482618
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ayse Guc
Stroke, Complex Regional Pain Syndrome
Contrast Compression Therapy for Post-Stroke Complex Regional Pain Syndrome
This study aims to evaluate the effectiveness of contrast compression therapy as an adjunct to conventional rehabilitation in patients diagnosed with complex regional pain syndrome (CRPS) following stroke.
- Conditions
- Stroke, Complex Regional Pain Syndrome, Hemiplegia
- Trial name
- NCT07062913
- Testing
- Conventional Rehabilitation, Contrast Compression Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Meltem Gunes Akinci
RSD (Reflex Sympathetic Dystrophy), Algodystrophy
Prophylactic Administration of Vitamin C in Wrist Fractures
Complex Regional Pain Syndrome or posttraumatic dystrophy is a pain syndrome which develops after a trauma, surgery or for unknown reason. The incidence after wrist fractures varies in literature from 2 - 37%.
- Conditions
- RSD (Reflex Sympathetic Dystrophy), Algodystrophy, CRPS Type I
- Trial name
- NCT00296868
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Stichting Achmea Slachtoffer en Samenleving
Fibromyalgia Syndrome
Efficacy of S-Adenosylmethionine in Fibromyalgia
Fundamentally, the trial aims to conduct a gold-standard test of the clinical impact of SAM-e in the treatment of depressed mood and general symptoms of fibromyalgia (FMS).
- Trial name
- NCT00528710
- Testing
- SAM-e (S-Adenosyl-L-Methionine)
- Where
- Australia
- Volunteers
- 70 people
- Sponsor
- Deakin University
Amyotrophic Lateral Sclerosis
Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis (STEMALS)
A Not for Profit Phase II Study to Evaluate Safety, Efficacy and Biomarkers secondary endpoints of Human Neural Stem cell intracerebroventricular transplantation in amyotrophic lateral sclerosis patients: a randomized, placebo…
- Trial name
- STEMALS (NCT06344260)
- Testing
- human Neural Stem Cells (hNSC)
- Where
- 4 sites in Italy
- Volunteers
- 30 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Diabetic Neuropathy
FDGL Dose-Finding Study for Diabetic Neuropathy
This study investigates the optimal dose of fermented deglycyrrhizinated licorice (FDGL) that maximizes both safety and efficacy in managing diabetic neuropathy complications in adults.
- Trial name
- NCT07117942
- Testing
- Fermented Deglycyrrhizinated Licorice (FDGL)
- Where
- Egypt
- Volunteers
- 485 people
- Sponsor
- Helwan University
Fibromyalgia, Irritable Bowel Syndrome
Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders
Objectives : To investigate the analgesic effects of repeated sessions of unilateral rTMS in patients with chronic pain syndrome due to fibromyalgia, IBS or burning mouth syndrome. Primary outcome will be numerical pain scores.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Burning Mouth Syndrome
- Trial name
- NCT00374673
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospital Ambroise Paré Paris
Healthy, Primary Immune Thrombocytopenia
A First in HumanTrial to Evaluate The Safety, Tolerability, And Pharmacokinetics Of PF-06755347
This phase 1 single ascending dose study will provide a first in human assessment of safety and tolerability of PF-06755347 in healthy adult males as well as adult males and females with Immune Thrombocytopenia (ITP).
- Conditions
- Healthy, Primary Immune Thrombocytopenia, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
- Trial name
- NCT03275740
- Testing
- PF-06755347 intravenous healthy participant, PF-06755347 subcutaneous healthy participant, PF-06755347 subcutaneous ITP
- Where
- 6 sites in United States, Belgium and 3 more
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Pfizer