Clinical trials: Neuromuscular Blockade Monitoring
Neuromuscular Blockade Monitoring
The Staircase Phenomenon Implications on Neuromuscular Block Monitoring
The staircase phenomenon could have repercussions on the onset and recovery time following administration of a neuromuscular blocking agent.
- Trial name
- NCT03146767
- Testing
- Tetanus stabilization of baseline
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario La Fe
Postoperative Residual Curarization, Neuromuscular Blockade
Comparison of Adductor Pollicis and Abductor Digiti Minimi Muscles (Thumb Vs. Fifth Digit) As Sites for Neuromuscular Monitoring with Electromyography
This study aims to evaluate the performance of the TetraGraph on two muscle groups: the adductor pollicis and the abductor digiti minimi. Theese muscles are located on the arms.
- Trial name
- NCT06691204
- Where
- 2 sites in Hungary
- Volunteers
- 46 people
- Sponsor
- Tamas Vegh, MD
Neuromuscular Blockade
Validation of a Muscle Relaxation Monitor
The objective of this study is to determine the accuracy of a hydraulically coupled twitch monitor compared to the EMG twitch monitor in current use to measure the extent of neuromuscular blockade in patients undergoing general…
- Trial name
- NCT03052894
- Testing
- Hydraulic Monitoring Device, Standard EMG Monitoring Device
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Richard H Epstein
Polyneuropathies
Diagnostic Feasibility of 100 Hz Tetanic Stimulation
The goal of this observational study is to investigate the applicability of 100 Hz tetanic stimulation with an electromyography device in the exclusion of postoperative residual neuromuscular block.
- Trial name
- NCT06754995
- Where
- 2 sites in Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Attention, Electroencephalography
Shaolin Dan Tian Breathing Fosters Relaxed and Attentive Mind
The present study aimed to utilize these well-known neuroelectrophysiological techniques to investigate the relatively less studied Shaolin Dan Tian Breathing (DTB) technique.
- Trial name
- NCT00988702
- Testing
- Dan Tian Breathing, Progressive muscle training
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Residual Paralysis, Post Anesthesia, Postoperative Complications
Predicting Neuromuscular Recovery in Surgical Patients Using Machine Learning
Despite emerging efforts to decrease residual paralysis and postoperative complications with the use of quantitative neuromuscular monitoring and reversal agents their incidences remain high.
- Conditions
- Residual Paralysis, Post Anesthesia, Postoperative Complications, Neuromuscular Blockade, Quantitative Neuromuscular Monitoring
- Trial name
- PINES (NCT05471882)
- Where
- 2 sites in Germany
- Volunteers
- 240,000 people
- Sponsor
- University Hospital Ulm
Chronic Otitis Media, Anesthesia
Optimal Dose of Combination of Rocuronium and Cisatracurium
BACKGROUND: The combinations of rocuronium and cisatracurium have a synergic effect. The investigators studied whether the prediction is possible to have a sufficient effect of reducing the dose when combining the two…
- Trial name
- CRC (NCT02495038)
- Testing
- 10% reduction of combination of Esmeron® and Nimbex®, 20% reduction of combination of Esmeron® and Nimbex®
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Residual Paralysis, Post Anesthesia
Best Management of Muscle Relaxation- Objective Monitoring
The purpose of this study is to demonstrate that the investigators can reduce residual paralysis to a very low incidence, and that the investigators can do this while preserving a role for the older and less expensive reversal…
- Trial name
- NCT03958201
- Testing
- Protocol for Management of Muscle Relaxation With Rocuronium Using Objective Monitoring and Reversal With Neostigmine or Sugammadex
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Washington
Neuromuscular Blockade, Residual Neuromuscular Blockade
Neuromuscular Blockade Monitoring Using Kine-myography vs Electromyography.
This study aims to compare two monitoring methods of neuromuscular blockade - Kine-myography and Electromyography. The main questions to answer are: are electromyography and kine-myography interchangeable is electromyography…
- Trial name
- NCT05992090
- Where
- Czechia
- Volunteers
- 129 people
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Neuromuscular Block, Residual
Monitoring of Postoperative Residual Neuromuscular Blockade in Laparoscopic Surgery
Compare the reversal effect of neostigmine and sugammadex using quantitative neuromuscular monitoring
- Trial name
- NCT03292965
- Testing
- Neostigmine, Sugammadex
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Major Depressive Disorder, Bipolar Disorder
Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT
This prospective, open-label clinical trial aims to compare a novel "Venous Tourniquet with Regional Low-Dose Sugammadex" method against the gold standard "Arterial Tourniquet" (Isolated Forearm Technique - IFT) for monitoring…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Schizophrenia
- Trial name
- NCT07534475
- Testing
- Device: Arterial Tourniquet, Device: Venous Tourniquet, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Thyroid Surgery
Neuromuscular Block Monitoring During Monitored Thyroidectomy
Titration of neuromuscular block (NMB) plays a key role in intraoperative recurrent laryngeal nerve monitoring during thyroid surgery.
- Trial name
- NCT04982185
- Where
- Taiwan
- Volunteers
- 116 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Hemifacial Spasm, Microvascular Decompression
Determination of Target of Adequate Partial Neuromuscular Blockade for Electrophysiologic Monitoring During Microvascular Decompression Surgery
There have been reports of monitoring LSR during MVD surgery helps predicting the clinical outcome of MVD.However, there have been no evidence of which degree of partial neuromuscular blockade should be performed or no…
- Conditions
- Hemifacial Spasm, Microvascular Decompression, Lateral Spread Response Monitoring
- Trial name
- NCT01598961
- Testing
- TOF count-guided partial NMB, T1/Tc guided partial NMB, No NMB
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Samsung Medical Center
Thyroid, Neuromuscular Blockade
Anaesthesia With or Without Rocuronium in Intubation and Intraoperative Nerve-monitoring During Thyroid Surgery.
In this randomized controlled trial the investigators want to assess if, compared to controls, the administration of one single low-dose of rocuronium would increase the occurrence of absent or weak (i.e.
- Conditions
- Thyroid, Neuromuscular Blockade, Anesthesia Complication, Anesthesia Intubation Complication
- Trial name
- NCT03910504
- Testing
- Rocuronium 0.3 mg*kg, No Rocuronium
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Federico Longhini
Cholecystectomy, Laparoscopic
Neuromuscular Block and Anesthetic Depth Monitoring
The purpose of this study is to evaluated whether the depth of neuromuscular block may affect the unicon value of anesthetic depth monitoring system (ADMS).
- Trial name
- NCT02575443
- Testing
- Rocuronium (MB group), Rocuronium (DB group)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Bundang Hospital
Surgery, Neuromuscular Blockade
TetraGraph to Evaluate Onset and Recovery Times of Rocuronium
In most clinical instances, direct laryngoscopy and endotracheal intubation is performed after a set time (generally 60 seconds) following the administration of a neuromuscular (NM) blocking agent, rocuronium.
- Trial name
- NCT07435792
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Nationwide Children's Hospital
Neuromuscular Blockade
Mindray Neuromuscular Transmission Transducer
A new NMT module from Mindray (Mindray Co. Shenzhen, People's Republic of China.) claims to measure 3 directional accelerography.
- Trial name
- NMT1 (NCT02892045)
- Testing
- MMG
- Where
- 2 sites in Bosnia and Herzegovina, China
- Volunteers
- 48 people
- Sponsor
- Suez Canal University
Laparoscopic Colorectal Surgeries
Impact of Intraoperative Deep Neuromuscular Blockade on NOL-guided Opioid Requirement in LSC Colorectal Surgeries
The aim of the present study is to answer the question whether deep neuromuscular blockade has a clinically significant impact on intra and postoperative pain, opioid requirement and anesthesia related outcomes and side effects…
- Trial name
- NCT03910998
- Testing
- Rocuronium IV bolus 0.1 mg/kg guided by TOF that must remain between 1-3 during surgery, Rocuronium IV bolus 0.1 mg/kg guided by TOF 0/4 and PTC≤ 2
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Cerebellopontine Angle Tumor
Compare the Operating Condition of Two Levels of Muscle Relaxation on Facial Nerve MEP Monitoring in CPA Surgery
compare the operating condition of two different levels of muscle relaxation on facial nerve monitoring using transcranial motor evocked potential in CPA surgery .
- Trial name
- NCT04148534
- Testing
- Rocroniom, Non Depolarizing Muscle Relaxant
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Muhammad Magdy Gaber
Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
Observational Study to Evaluate the Current Neuromuscular Monitoring Practice Used After Different Types of Surgery, for Which Neuromuscular Blocking Agents Were Used, With or Without Blocking Reversal (P06556)
The intent of this observational study is to collect prospective data regarding neuromuscular monitoring practices and extubation standards (Train-Of-Four [TOF] value) during surgery, in countries of Central and Eastern Europe…
- Trial name
- NCT01213264
- Testing
- No neuromuscular blockade (NMB)-reversal agent used, Sugammadex, Other NMB-Reversal Agents Used in Routine Anesthesiology Practice
- Volunteers
- 659 people
- Sponsor
- Merck Sharp & Dohme LLC