Clinical trials: Neuromuscular Blockade
Progressive Muscle Relaxation
Acute Effects of Progressive Muscle Relaxation on Brain Waves
In modern environments, stress is present regardless of age or social role. Stress does not always have negative effects; in fact, it is a necessary response for survival, known as the stress response.
- Trial name
- NCT07089537
- Testing
- progressive muscle relaxaiton, Rest
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Peripheral Chemosensitivity
The Breath-2 Trial
This is a randomized, cross over, experimental trial in which carotid body function will be evaluated in 35 healthy subjects during partial muscle relaxation and after recovery from muscle relaxation
- Trial name
- NCT05149872
- Testing
- Muscle relaxation, Reversal
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Neuromuscular Block, Residual, Pain
Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults
This randomized controlled trial aims to compare the effects of intravenous methylprednisolone and dexamethasone on the reversal time of rocuronium by sugammadex in adult patients undergoing elective septoplasty or rhinoplasty.
- Conditions
- Neuromuscular Block, Residual, Pain, Postoperative Nausea
- Trial name
- NCT07187037
- Testing
- Methylprednisolone (MP), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Restless Legs Syndrome
The Effect of Progressive Muscle Relaxation Exercise Training Given to Pregnant Women With Restless Leg Syndrome
Restless Leg Syndrome (RLS) is a sensory-motor problem characterized by an uncomfortable and unpleasant feeling that causes a strong and overwhelming desire to move the legs, usually during periods of inactivity during sleep.It…
- Trial name
- NCT04853771
- Testing
- progressive muscle relaxation exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gazi University
Neuromuscular Blockade
The Effect of Magnesium Sulphate on the Time Course of Rocuronium Induced Neuromuscular Block
The aim of this study is to investigate whether an optimized pre-treatment with intravenous magnesium enhances the speed of onset of a standard intubation dose of rocuronium.
- Trial name
- MagRoc (NCT00405977)
- Testing
- Physiologic saline, Magnesium sulphate
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Hemodialysis Complication, Hemodialysis
The Effect of Progressive Muscle Relaxation Exercises on Depression and Fatigue in Patients Receiving Hemodialysis Treatment: A Randomized Controlled Trial
This study aims to evaluate the effects of progressive muscle relaxation exercises on depression and fatigue levels in patients undergoing hemodialysis treatment.
- Trial name
- NCT07512895
- Testing
- Progressive Muscle Relaxation Intervention
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Driving Pressure, Neuromuscular Blockade Monitoring
Effect of Neuromuscular Block Depth on Driving Pressure and Postoperative Respiratory Events in Abdominal Surgeries
This randomized controlled study aims to evaluate the effects of deep versus moderate neuromuscular blockade on intraoperative driving pressure and the development of postoperative critical respiratory events in patients…
- Conditions
- Driving Pressure, Neuromuscular Blockade Monitoring, Postoperative Respiratory Complications
- Trial name
- NCT07464288
- Testing
- Rocuronium
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Neuromuscular Blockade Reversal Agent, Perioperative Complications
Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal
Study Objective: This study aims to evaluate the incidence, severity, and risk factors of sugammadex-induced mouth clenching during neuromuscular blockade (NMB) reversal in adult surgical patients.
- Conditions
- Neuromuscular Blockade Reversal Agent, Perioperative Complications, Anesthesia, General, Sugammadex
- Trial name
- NCT06962007
- Testing
- Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group
- Where
- South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Neuromuscular Blockade, Neuromuscular Blockade, Residual
Three Different Doses of Neostigmine on the Reversal of Cisatracurium-induced Moderate Neuromuscular Blockade
The aim of the present study will be to evaluate by means of a prospective randomized clinical trial, the time required for the reversal of moderate neuromuscular blockade (NMB) (Train-of-four count = 3; TOFc 3) to Train-of-four…
- Trial name
- NCT05037006
- Testing
- Sevoflurane - Neostigmine 30, Sevoflurane - Neostigmine 50, Sevoflurane - Neostigmine 70
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Rheumatoid Arthritis, Osteoarthritis
Low Dose Dexamethasone in Supraclavicular Blocks
Brachial plexus nerve blocks provide superior analgesia over opioids while avoiding unwanted side effects. Single shot blocks with local anesthetic alone usually do not last the duration of the acute post-surgical pain period.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Nerve Entrapment, Ligament Injury
- Trial name
- NCT02666443
- Testing
- Control intervention (no dexamethasone), Peri-neural Dexamethasone 1 mg, Intravenous Dexamethasone 1 mg
- Where
- Canada
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Residual Neuromuscular Blockade
Residual Neuromuscular Blockade in Cardiac Surgery Patients
The purpose of this project is to determine if reversal of neuromuscular blockade in cardiac surgery patients expedites time to extubation in fast track patients.
- Trial name
- NCT03574337
- Testing
- Sugammadex, neostigmine/glycopyrolate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Neuromuscular Blockade, Neuromuscular Block, Residual
Different Doses of Neostigmine for Reversal of Moderate Neuromuscular Blockade in Children
There is no recent information on the required dose of neostigmine for the reversal of cisatracurium-induced moderate neuromuscular blockade (NMB) [Train-of-four (TOF) count = 1-3)] in children.
- Conditions
- Neuromuscular Blockade, Neuromuscular Block, Residual, Neuromuscular Block Prolonged
- Trial name
- NCT05053594
- Testing
- Neostigmine 10 mcg/kg, Neostigmine 20 mcg/kg, Neostigmine 30 mcg/kg
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Attention, Electroencephalography
Shaolin Dan Tian Breathing Fosters Relaxed and Attentive Mind
The present study aimed to utilize these well-known neuroelectrophysiological techniques to investigate the relatively less studied Shaolin Dan Tian Breathing (DTB) technique.
- Trial name
- NCT00988702
- Testing
- Dan Tian Breathing, Progressive muscle training
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hamstring Contractures, Muscle Relaxation
Dynamic Stretching vs. Foam Rolling: Effects on Hamstring Flexibility and Muscle Oxygenation in Tight Hamstrings
Hamstring muscle flexibility plays a vital role in functional movement and in the prevention of injuries. Reduced flexibility of the hamstring muscles is common and can lead to biomechanical dysfunctions, a limited range of…
- Conditions
- Hamstring Contractures, Muscle Relaxation, Muscle Tightness
- Trial name
- NCT07024017
- Testing
- Foam roller, dynamic stretch
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Pelin Pişirici
Muscle Relaxation
Stretching vs Foam-rolling
The study aims to compare the acute effects of the aplication of foam-rolling and stretching over the hamstrings flexibility. The secondary objective is to determine which time can permit the obtention of better results.
- Trial name
- NCT03573895
- Testing
- Foam-Roller, Neuromuscular stretching, Pasive stretching
- Where
- Spain
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Neuromuscular Blockade
Pilot Study on the Pharmacodynamics of Sugammadex in Morbidly Obese Patients: Reversal of Deep Neuromuscular Blockade
Should the dose of sugammadex in morbid obese patients be calculated on the real body weight or the ideal body weight? To study the pharmacodynamics of sugammadex in morbidly obese patients by comparing 1 mg/kg IBW versus 1 mg/kg…
- Trial name
- MOS (NCT01855217)
- Testing
- Sugammadex
- Where
- Netherlands
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Anxiety, Stress
The Effect of Music Therapy and Progressive Muscle Relaxation Exercise on Anxiety Before the First Clinical Practice
This study was carried out to evaluate the effect of music therapy and progressive muscle relaxation exercise on the state and trait anxiety levels before their first clinical practice in nursing students.
- Trial name
- NCT04540172
- Testing
- Music Therapy, Progressive Muscle Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Stress Urinary Incontinence (SUI)
Pelvic Floor Muscle Exercise and Progressive Muscle Relaxation for Stress Urinary Incontinence
Stress urinary incontinence (SUI) is a common condition in women that causes involuntary urine leakage during activities such as coughing, sneezing, laughing, or exercising.
- Trial name
- NCT07762391
- Testing
- Pelvic Floor Muscle Exercise, Progressive Muscle Relaxation (PMR), Combined Pelvic Floor Muscle Exercise and Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Neuromuscular Blocking Agents, Urinary Retention After Procedure
NMBA Reversal and Postoperative Urinary Retention
In this single-center retrospective cohort study of adult patients who underwent surgery under general anesthesia at Beth Israel Deaconess Medical Center between September 2016 and January 2024, the association between the choice…
- Conditions
- Neuromuscular Blocking Agents, Urinary Retention After Procedure, Urinary Retention Postoperative, Neuromuscular Blockade Reversal Agent
- Trial name
- NCT06948409
- Testing
- Choice of reversal agent (sugammadex or neostigmine [with muscaranic antagonist])
- Where
- United States
- Volunteers
- 70,000 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Premenstrual Syndrome
The Effect of Su-Jok Application and Progressive Muscle Relaxation Exercises in Coping With Premenstrual Syndrome
The aim of this study is to determine the effect of su-jok application and progressive muscle relaxation exercise in coping with premenstrual syndrome.
- Trial name
- NCT06296043
- Testing
- Progressive Muscle Relaxation Exercise Group, Su-Jok Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi