Clinical trials: Neurological Observations
Cancer
Laboratory Assay in Determining Cancer Resistance in Patients With Metastatic Cancer and in Healthy Participants
RATIONALE: Studying samples of blood and tissue in the laboratory from patients with cancer and from healthy participants may help doctors learn more about cancer.
- Trial name
- NCT00899496
- Testing
- immunological diagnostic method, physiologic testing
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Diabetic Peripheral Neuropathy
Exercise Effects on Pain, Sleep and Depression in Diabetic Peripheral Neuropathy
It is known that the pain experienced by individuals with diabetic neuropathy negatively impacts sleep and quality of life, leading to numerous psychosocial problems such as anxiety and depression.
- Trial name
- NCT07291596
- Testing
- Ankle-Foot Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Amasya University
Thoracic Outlet Syndrome, Mechanically Loaded Neuro-dynamics
Effect of Mechanically Loaded Neuro-dynamics in Subjects With Thoracic Outlet Syndrome
the study was done to: To assess the effect of Mechanically Loaded Neuro-dynamics on pain reduction in subjects with thoracic outlet syndrome.
- Trial name
- NCT07785427
- Testing
- Mechanically Loaded Neuro-dynamics, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kafrelsheikh University
Stroke
Effect of Non-invasive Vagus Nerve Stimulation on Cerebrovascular Reactivity and Cognition in Chronic Stroke Patients
This study will be conducted to assess the effect of non-invasive vagus nerve stimulation on cerebrovascular reactivity and cognition in chronic stroke patients
- Trial name
- NCT07626242
- Testing
- Trans-auricular vagus nerve stimulation, Conventional physical therapy, Computer based cognitive rehabilitation training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Vibration, Electrophysiology
Developing Optimal Focal Muscle Vibration for Improving Spasticity
The overall aim of the proposed study is to determine optimal parameter of focal muscle vibration for improving spasticity and identify neurophysiological mechanism in healthy subjects.
- Conditions
- Vibration, Electrophysiology, Muscle Spasticity
- Trial name
- NCT01915342
- Testing
- Focal muscular vibration
- Where
- South Korea
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Paresis
Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Background: Outpatient continuous interscalene brachial plexus blocks are used to control pain after shoulder surgery, with infusions of 0.125% bupivacaine or 0.2% ropivacaine.
- Trial name
- NCT02059070
- Testing
- Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Anesthesiology WSU/DMC-NorthStar
Brain Tumor
The Use of Fentanyl in General Anesthesia for Craniotomy With or Without 0.5% Levobupivacaine Scalp Block
This study evaluates the use of fentanyl during craniotomy in two groups of brain tumor patients. The control group will receive standard general anesthesia with the use of fentanyl for intraoperative pain control and the study…
- Trial name
- NCT02558569
- Testing
- Levobupivacaine, NSS
- Where
- 2 sites in Thailand
- Volunteers
- 128 people
- Sponsor
- Mahidol University
Gynecologic Cancer, Neuropathy;Peripheral
The Effect of Low Frequency Soundwave Stimulation on Chemotherapy Induced Peripheral Neuropathy
The goal of this clinical trial is to assess the efficacy of SensoniQ® Treatment Station in preventing or reducing chemotherapy induced peripheral neuropathy symptoms (CIPNS) in patients receiving frontline carboplatin and…
- Trial name
- NCT05980169
- Testing
- SensoniQ Treatment Station
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Augusta University
Developmental Disabilities, Sleep Disorders
Use of an Educational Story to Prepare Children With Developmental Disabilities for Sleep Study
The investigators hypothesize that use of an educational story with pictures illustrating overnight sleep study procedure (also called polysomnography or PSG)accompanied by simple narrative will be a cost-effective, readily…
- Conditions
- Developmental Disabilities, Sleep Disorders, Polysomnography, Preparation for Medical Procedure
- Trial name
- NCT02132273
- Testing
- Educational Story
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jennifer Accardo
Migraine Headaches
To Evaluate the Safety and Efficacy of Trexima in the Acute Treatment of Migrane Headaches
to demonstrate the superiority of Trexima (combination of sumatriptan as the succinate 85 mg and naproxen sodium 500 mg) versus placebo in the acute treatment of migraine to demonstrate the superiority of Trexima versus the…
- Trial name
- NCT00434083
- Testing
- sumatriptan, naproxen sodium
- Where
- 2 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- POZEN
Chronic Fatigue Syndrome
Structural Problems in Brainstem and Cervical Spine Cord in ME/CFS
A case control study on patients with ME/CFS and healthy controls on prevalence of cervical obstructions, Cerebro spinal fluid (CSF) pressure and laboratory findings.
- Trial name
- NCT04403854
- Testing
- MRI, Spinal Tap
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bragee Clinics
Hereditary Angioedema
Autonomic Nervous System Profile in Hereditary Angioedema
The goal of this study is to compare the autonomic nervous system control of patients with hereditary angioedema to healthy individuals.
- Trial name
- ANS-HAE (NCT06408805)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Tetraplegia, Hypothermia
Body Temperature in Persons With Tetraplegia When Exposed to Cold
The ability to maintain normal body core temperature (Tcore = 98.6°F) is impaired in persons with tetraplegia. Despite the known challenges to the ability of persons with spinal cord injury (SCI) to maintain Tcore, and the…
- Conditions
- Tetraplegia, Hypothermia, Mild Cognitive Impairment
- Trial name
- NCT01822535
- Testing
- Midodrine hydrochloride
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Women in the Menopausal Period
Effect of Sleep Hygiene Education on Comfort and Sleep Quality in Menopausal Women
The decrease in estrogen levels in the body during menopause can lead to sleep disturbances by disrupting serotonin metabolism, which plays an important role in regular sleep.
- Trial name
- NCT06884917
- Testing
- Sleep Hygiene Training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Neuropathic Pain
Ketamine and Neuropathic Pain
The primary outcome is to compare the analgesic efficacy of intravenous ketamine treatment to that of a placebo in patients with refractory neuropathic pain. The secondary outcomes are: 1.
- Trial name
- KETAPAIN (NCT02467517)
- Testing
- Ketamine, Magnesium Sulfate
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemiplegic Shoulder Pain
Bobath Approach On Hemiplegic Shoulder Pain
In this study, it is investigated that whether Bobath approach is superior to conventional physiotherapy in terms of improving hemiplegic shoulder pain, spasticity and upper extremity functionality in stroke patients.
- Trial name
- BAHSP (NCT04768140)
- Testing
- Bobath treatment approach, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Arel University
Parkinson Disease
Chest PNF on Pulmonary Function in Parkinson Disease
Background: Parkinson disease (PD) is a progressive neurodegenerative disorder and characterized by tremor, rigidity and bradykinesia.
- Trial name
- NCT03977740
- Testing
- chest PNF, Conventional
- Where
- India
- Volunteers
- 20 people
- Sponsor
- Subhasish Chatterjee
Hereditary Tyrosinemia, Type I
Taste and Palatability of Orfadin Suspension
The purpose of this study is to verify that pediatric patients, especially those who are not old enough to swallow capsules, accept the taste and palatability of a new suspension.
- Trial name
- NCT01734889
- Testing
- Nitisinone
- Where
- 7 sites in France, Germany and 1 more
- Volunteers
- 18 people
- Sponsor
- Swedish Orphan Biovitrum
Stuttering/ Developmental
The Effect of the Non-invasive Brain Stimulation on the Speech Fluency Enhancement
The aim of this study is to determine the effectiveness of concurrent transcranial direct current stimulation (tDCS) and fluency training in adults with developmental stuttering.
- Trial name
- NCT03990168
- Testing
- Anodal tDCS, fluency intervention/ Delayed Auditory Feedback
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Iran University of Medical Sciences
Anosmia, COVID-19
Characteristics of the Anosmic Olfactory Mucosa
The present study aims to describe the structural tissue and cell characteristics of the olfactory mucosa in patients with persistent anosmia (≥2 years) due to COVID-19 or head-trauma, in comparison to healthy individuals with…
- Conditions
- Anosmia, COVID-19, Head Injury
- Trial name
- NCT05562050
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- Nicolai Nielsen