Clinical trials: Neurological Conditions
Anxiety Disorder, Breast Cancer
Cranial Stimulation for Chemotherapy Symptoms in Breast Cancer
RATIONALE: Cranial microcurrent electrical stimulation (CES) is mild electrical current received through electrodes placed on the earlobes. CES may lessen symptoms in women with breast cancer receiving chemotherapy.
- Conditions
- Anxiety Disorder, Breast Cancer, Depression, Fatigue
- Trial name
- NCT00902330
- Testing
- energy-based therapy
- Volunteers
- 161 people
- Sponsor
- Virginia Commonwealth University
Osteoarthritis, Total Knee Arthroplasty
Effectiveness of Intraoperative Exparel for Postoperative Pain Control in Total Knee Arthroplasty
Does the use of periarticular Exparel in total knee arthroplasty prove to more effectively manage post operative pain control than another local analgesic, Ropivacaine, when both are used as part of a multimodal pain management…
- Conditions
- Osteoarthritis, Total Knee Arthroplasty, Pain Management
- Trial name
- NCT02808728
- Testing
- Pain Cocktail with Exparel, Pain Cocktail with Ropivacaine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- DeClaire LaMacchia Orthopaedic Institute
Pain Thresholds
Does Boredom With Simultaneously Perceived Pain Affect Pressure Pain Thresholds
The purpose of this study is to investigate if different emotional states such as boredom and happiness could influence mechanical pain thresholds and other pain - related variables such as pain tolerance, pain intensity and pain…
- Trial name
- BPPPT (NCT07330167)
- Testing
- Boredom intervention, Humorous
- Where
- Sweden
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Osteoarthritis, Knee
The Effect of Dry Needling in Patients With Knee Osteoarthritis
Research suggests that myofascial trigger points (MTrP) play an important role in explaining pain in patients with musculoskeletal knee disorders.
- Trial name
- NCT04717167
- Testing
- Dry Needling
- Volunteers
- 61 people
- Sponsor
- Universiteit Antwerpen
Pain, Chronic Primary
Pain and Clinical Reflections in Pelvic Congestion Syndrome
Pelvic congestion syndrome (PKS) occurs as a result of dysfunction of the veins in the pelvic area. It is currently called pelvic venous disease.
- Trial name
- NCT06507267
- Testing
- Pain and Clinical Reflections in Pelvic Congestion Syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Fibromyalgia
Brain Rhythms in Fibromyalgia: A Magnetoencephalography (MEG) Study
The long-term purpose of the investigator's research is to understand the pathophysiological basis of chronic pain. This will help provide a framework for the development of effective treatments.
- Trial name
- FMP (NCT02159300)
- Testing
- experience brain activity recording
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stroke, COVID-19
Strength Training in Hospitalized Patients Using the Ghostly App: a Feasibility Study
The goal of this feasibility study is to evaluate the use of the Ghostly app in rehabilitation of stroke patients, elderly and patients recovering from COVID-19 or ICU patients.
- Conditions
- Stroke, COVID-19, Frailty, Muscle Weakness
- Trial name
- NCT05258500
- Testing
- Ghostly app, Blood flow restriction, Leaflet
- Where
- 2 sites in Belgium
- Volunteers
- 15 people
- Sponsor
- Vrije Universiteit Brussel
Chronic Coronary Syndrome, Angina Pectoris
Personalized Evaluation of Susptected Myocardial Ischemia
This study aims to assess whether the use of clinical risk models, known as Clinical Likelihood (CL) models, can reduce the need for diagnostic examinations without negatively impacting quality of life or prognosis after 12…
- Conditions
- Chronic Coronary Syndrome, Angina Pectoris, Coronary Artery Disease, Myocardial Ischemia
- Trial name
- PERMI (NCT06708000)
- Testing
- Clinical Likelihood (CL) Model-Based Diagnostic Strategy, Standard of care treatment
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Gødstrup Hospital
Hand Massage
The Effect of the Hand Massage A Women Undergoing Brachytherapy
Background Gynecologic cancers are among the ten most common cancers among women. During brachytherapy, women can have pain and situational anxiety due to the treatment.
- Trial name
- NCT05937607
- Testing
- Hand massage
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Sarcopenia
The Influence of Daily Grapes Intake on Sarcopenia in Postmenopausal Women
Sarcopenia, characterized by loss of muscle mass and function, is a prevalent disorder in elderly individuals or individuals with chronic diseases.
- Trial name
- NCT05863507
- Testing
- Grape powder supplementation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Hearing Loss
Bilateral Cochlear Implant Benefit in Young Children
The primary purpose of this study is to track patient outcomes for bilateral cochlear implant recipients in a cohort of 60 children, ages 12 to 36 months at time of surgery, who receive two implants in the same operation or in…
- Trial name
- NCT00424307
- Testing
- HiResolution Bionic Ear System
- Where
- 14 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Advanced Bionics
Mastectomy, Pain, Acute
Stellate Ganglion Block for Prevention of Post Mastectomy Depression
Complications after mastectomy include chronic pain and depression.
- Conditions
- Mastectomy, Pain, Acute, Pain, Chronic
- Trial name
- SGB (NCT06263907)
- Testing
- Stellate gangalion block
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Mansoura University
Arthralgia, Pain
Role of Biomarkers in Muscle Pain and Joint Pain in Patients With Solid Tumors Receiving Paclitaxel
RATIONALE: Learning about pain in patients with cancer receiving paclitaxel may help plan treatment and may help patients live more comfortably.
- Conditions
- Arthralgia, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT01096407
- Testing
- laboratory biomarker analysis, questionnaire administration, assessment of therapy complications
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Depression - Major Depressive Disorder, Catatonia
Optimizing Stimulation Parameters for Electroconvulsive Therapy
The goal of this clinical trial is to improve how electroconvulsive therapy (ECT) stimulation settings are chosen. Researchers will use real-time brain monitoring to measure both seizures and a recently identified brain event…
- Trial name
- PRESTO (NCT07561307)
- Testing
- Electroconvulsive Therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Pennsylvania
Convulsion, Non-Epileptic
Treatment Outcomes of ReACT for PNES
This research study is examining the effects of Retraining and Control Therapy (ReACT; an intervention focused on changing behaviors and thoughts) for psychogenic non-epileptic seizures (PNES, episodes resembling epileptic…
- Trial name
- NCT02801136
- Testing
- ReACT, Supportive Therapy
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Shoulder Pain, Laparoscopic Surgery
Reducing Shoulder Tip Pain Following Laparoscopic Surgery
Laparoscopic surgery is becoming a major procedure, owing to smaller incisions, shorter hospitalizations, and less post-operative pain as compared with traditional laparotomies.
- Trial name
- NCT01135836
- Testing
- Pulmonary recruitment maneuver, Intraperitoneal normal saline, Control group
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Joint Pain, Knee Osteoarthritis
Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute Exacerbation
This is a Phase III, longitudinal, multicenter, randomized, double-blind clinical trial designed to evaluate the efficacy and safety of a fixed-dose combination of celecoxib and acetaminophen compared to celecoxib monotherapy for…
- Conditions
- Joint Pain, Knee Osteoarthritis, Hip Osteoarthritis
- Trial name
- PRECEDENT (NCT06863636)
- Testing
- Celecoxib + Acetaminophen, Celecoxib
- Where
- Mexico
- Volunteers
- 231 people
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Dysmenorrhea
Efficacy and Safety, Long-Term Study of NPC-16 to Treat Dysmenorrhea
The purpose of this long-term study is to determine whether NPC-16 is effective in the treatment of dysmenorrhea.
- Trial name
- NCT02362711
- Testing
- NPC-16 Standard Dosing Regimen Group, NPC-16 Continuous Dosing Regimen Group
- Volunteers
- 248 people
- Sponsor
- Nobelpharma
Hysteroscopy
Ultrasound Guidance of Office Hysteroscopy in Patients With History of Failure of Office Hysteroscopy Due to Cervical Stenosis.
The study is conducted to assess whether ultrasound guidance can facilitate the access of the office hysteroscope into the uterine cavity of patients with previous failure of office hysteroscopy due to cervical stenosis.
- Trial name
- NCT06637111
- Testing
- Ultrasound guided office hysteroscopy group, Conventional office hysteroscopy group
- Where
- 2 sites in Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Poly Cystic Ovary Syndrome
Effectiveness of Hatha Yoga With and Without Zumba Exercise on Clinical Outcomes in Females With Poly Cystic Ovarian Syndrome
Effectiveness of Hatha Yoga with and without Zumba exercise on clinical outcomes in females with Poly Cystic Ovarian Syndrome-Randomized Clinical Trial
- Trial name
- NCT07362771
- Testing
- Hatha Yoga, Zumba Exercise
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Rashid Latif Medical College