Clinical trials: Neurologic Findings
Ocular Inflammation and Pain
Efficacy and Safety of APP13007 for Treatment of Inflammation and Pain After Cataract Surgery
This Phase 3 study will evaluate APP13007 in comparison to the matching vehicle placebo in a randomized, parallel-group, double-masked fashion.
- Trial name
- NCT04739709
- Testing
- APP13007, 0.05%
- Where
- 35 sites in United States, Puerto Rico
- Volunteers
- 378 people
- Sponsor
- Formosa Pharmaceuticals, Inc.
Outpatient Orthopedic Surgery
Preoperative Education for Less Outpatient Pain After Surgery (PELOPS)
In 2015, more than 50% of surgical procedures were performed in outpatient settings. Successful pain management after outpatient surgery is crucial, and requires a perfect cooperation between caregivers and patients, with clear…
- Trial name
- PELOPS (NCT03754699)
- Testing
- Educational intervention, Standard information
- Where
- France
- Volunteers
- 412 people
- Sponsor
- Hospices Civils de Lyon
Down Syndrome
TheraTogs Versus Reciprocal Electrical Stimulation on Children With Diplegic Cerebral Palsy: a Randomized Controlled Trial
Children with diplegic cerebral palsy exhibit postural restrictions as a result of both primary and secondary brain damage impairments. One of the main goals of cerebral palsy rehabilitation is to improve balance and stability.
- Trial name
- NCT05702632
- Testing
- 1- Reciprocal electrical stimulation, TheraTogs orthotic treatment, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Cairo University
Reflex Syncope
Cardioneuroablation: Comparison of Right Versus Left Atrial Approach in Patients With Reflex Syncope
Introduction. Reflex vaso-vagal syncope (VVS) is the most frequent cause of transient loss of consciousness and it's treatment remains a challenge.
- Trial name
- ROMAN2 (NCT05225532)
- Testing
- Radiofrequency ablation
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Centre of Postgraduate Medical Education
Chronic Pain
Effect of Music Therapy on Pain
The aim of study is to assess the effects of this new music therapy technique on pain treatment, anxiety and depression and on medicinal consumption.
- Trial name
- NCT01020032
- Testing
- Individual receptive music therapy by "U sequence" method
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Association de Musicothérapie Applications et Recherches Cliniques
Locked- in Syndrome
A Method for Communication With Arabic Patients Suffering From Classic Locked- in Syndrome
Aim of the work The aim of this study is to test an Arabic alphabet communication system designed to train physicians to communicate with Arabic-speaking patients with LIS.
- Trial name
- NCT05444075
- Testing
- a method for communication
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Ataxia-Telangiectasia
Study for Treatment of Cancer in Children With Ataxia-telangiectasia
This is a pilot/feasibility study designed to investigate the feasibility of treating children with Ataxia-Telangiectasia (A-T) and cancer with regimens nearly as intense as non-A-T patients with cancer would receive.
- Trial name
- NCT00187057
- Testing
- vinblastine, vincristine, prednisone, daunorubicin, doxorubicin, methotrexate, cyclophosphamide, L-asparaginase, etoposide, cytarabine, mercaptopurine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- St. Jude Children's Research Hospital
Acute Myocardial Infarction, Pain
To Relieve Pain and Anxiety - an Intervention Study in Ambulance Services
This is an intervention study focusing on both medical and nursing questions. The study is a joint project between the Ambulance services at four cities in West Sweden and Knowledge and research centre, PreHospen at University of…
- Trial name
- NCT00792181
- Testing
- Midazolam, Course intervention - a professional development course for caregivers.
- Volunteers
- 2,800 people
- Sponsor
- Sahlgrenska University Hospital
Renal Stones, Postoperative Pain
Comparison of Tubeless Versus Standard Percutaneous Nephrolithotomy (PCNL) for Renal Stones
Percutaneous nephrolithotomy (PCNL) is the surgery usually done to break down kidney stones that are larger than 1.5 cm. Placing a nephrostomy tube after the surgery to drain urine is a common aspect of traditional PCNL.
- Trial name
- TPCNL (NCT07522619)
- Testing
- Standard Percutaneous Nephrolithotomy (Standard PCNL), Tubeless Percutaneous Nephrolithotomy (Tubeless PCNL)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Indus Hospital and Health Network
Knee Osteoarthritis, Pain Management
Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty
The purpose of the study is to compare magnitude of postsurgical analgesic effect in different groups following a single dose of study drug when administered via adductor canal block in subjects undergoing primary unilateral…
- Trial name
- NCT05139030
- Testing
- bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
- Where
- 6 sites in United States
- Volunteers
- 167 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Postpartum Hemorrhage, Pain
Do Elastic Abdominal Binders Reduce Post Operative Pain and Blood Loss?
This is a pilot study investigating the use of abdominal binders after cesarean sections. The researchers are testing whether elastic abdominal binders improve postoperative pain control and reduce postoperative blood loss.
- Trial name
- NCT01786330
- Testing
- Procare abdominal binder, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zachary Kuhlmann, DO
HIV
Evaluation of Neurologic and Psychiatric Adverse Events of Several Antiretroviral Drugs in Real Life Setting
The frequency of neurological and psychiatric complaints for participants taking rilpivirine, elvitegravir, or dolutegravir reaches on average 20-30% during clinical trials.
- Trial name
- NEPAL (NCT02882230)
- Testing
- prescription of at least one of the following drugs: rilpivirine, elvitegravir, dolutegravir
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Anxiety Disorder, Breast Cancer
Cranial Stimulation for Chemotherapy Symptoms in Breast Cancer
RATIONALE: Cranial microcurrent electrical stimulation (CES) is mild electrical current received through electrodes placed on the earlobes. CES may lessen symptoms in women with breast cancer receiving chemotherapy.
- Conditions
- Anxiety Disorder, Breast Cancer, Depression, Fatigue
- Trial name
- NCT00902330
- Testing
- energy-based therapy
- Volunteers
- 161 people
- Sponsor
- Virginia Commonwealth University
Osteoarthritis, Total Knee Arthroplasty
Effectiveness of Intraoperative Exparel for Postoperative Pain Control in Total Knee Arthroplasty
Does the use of periarticular Exparel in total knee arthroplasty prove to more effectively manage post operative pain control than another local analgesic, Ropivacaine, when both are used as part of a multimodal pain management…
- Conditions
- Osteoarthritis, Total Knee Arthroplasty, Pain Management
- Trial name
- NCT02808728
- Testing
- Pain Cocktail with Exparel, Pain Cocktail with Ropivacaine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- DeClaire LaMacchia Orthopaedic Institute
Pain Thresholds
Does Boredom With Simultaneously Perceived Pain Affect Pressure Pain Thresholds
The purpose of this study is to investigate if different emotional states such as boredom and happiness could influence mechanical pain thresholds and other pain - related variables such as pain tolerance, pain intensity and pain…
- Trial name
- BPPPT (NCT07330167)
- Testing
- Boredom intervention, Humorous
- Where
- Sweden
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Osteoarthritis, Knee
The Effect of Dry Needling in Patients With Knee Osteoarthritis
Research suggests that myofascial trigger points (MTrP) play an important role in explaining pain in patients with musculoskeletal knee disorders.
- Trial name
- NCT04717167
- Testing
- Dry Needling
- Volunteers
- 61 people
- Sponsor
- Universiteit Antwerpen
Pain, Chronic Primary
Pain and Clinical Reflections in Pelvic Congestion Syndrome
Pelvic congestion syndrome (PKS) occurs as a result of dysfunction of the veins in the pelvic area. It is currently called pelvic venous disease.
- Trial name
- NCT06507267
- Testing
- Pain and Clinical Reflections in Pelvic Congestion Syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Fibromyalgia
Brain Rhythms in Fibromyalgia: A Magnetoencephalography (MEG) Study
The long-term purpose of the investigator's research is to understand the pathophysiological basis of chronic pain. This will help provide a framework for the development of effective treatments.
- Trial name
- FMP (NCT02159300)
- Testing
- experience brain activity recording
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stroke, COVID-19
Strength Training in Hospitalized Patients Using the Ghostly App: a Feasibility Study
The goal of this feasibility study is to evaluate the use of the Ghostly app in rehabilitation of stroke patients, elderly and patients recovering from COVID-19 or ICU patients.
- Conditions
- Stroke, COVID-19, Frailty, Muscle Weakness
- Trial name
- NCT05258500
- Testing
- Ghostly app, Blood flow restriction, Leaflet
- Where
- 2 sites in Belgium
- Volunteers
- 15 people
- Sponsor
- Vrije Universiteit Brussel
Chronic Coronary Syndrome, Angina Pectoris
Personalized Evaluation of Susptected Myocardial Ischemia
This study aims to assess whether the use of clinical risk models, known as Clinical Likelihood (CL) models, can reduce the need for diagnostic examinations without negatively impacting quality of life or prognosis after 12…
- Conditions
- Chronic Coronary Syndrome, Angina Pectoris, Coronary Artery Disease, Myocardial Ischemia
- Trial name
- PERMI (NCT06708000)
- Testing
- Clinical Likelihood (CL) Model-Based Diagnostic Strategy, Standard of care treatment
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Gødstrup Hospital