Clinical trials: Neurodevelopmental Outcomes
Apnea of Prematurity, Intraventricular Hemorrhage
MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine
Over the last 30 years the survival rates for babies born prematurely have improved greatly with research. As these babies grow up, we have found that many of the premature babies have learning and movement problems.
- Conditions
- Apnea of Prematurity, Intraventricular Hemorrhage, Brain Injury
- Trial name
- NCT00809055
- Testing
- Caffeine citrate
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Washington University School of Medicine
Epilepsy, Pregnancy
Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD)
Epilepsy is one of the most common neurological disorders affecting women of childbearing age. Poor pregnancy outcomes are increased in these women and their children.
- Trial name
- MONEAD (NCT01730170)
- Where
- 20 sites in United States
- Volunteers
- 565 people, healthy volunteers welcome
- Sponsor
- Stanford University
Neonatal Patients Undergoing Major Non-cardiac Surgery, Congenital Anomaly
Neonatal Enhanced Recovery After Surgery (ERAS) Outcomes Study
The goal of this observational study is to improve the way newborn babies are cared for before, during, and after major surgery. Surgery can be very stressful on a baby's body.
- Trial name
- NEO (NCT07771478)
- Testing
- Pre-nERAS Guideline Implementation Intervention, Multifaceted Implementation of nERAS Guideline Intervention
- Where
- 3 sites in Canada, United Kingdom
- Volunteers
- 400 people
- Sponsor
- The Hospital for Sick Children
Autism Spectrum Disorder
Optimizing Social and Communication Outcomes for Toddlers With Autism
This project will examine the efficacy of two different treatment approaches aimed at facilitating change in social and communications outcomes of toddlers with autism.
- Trial name
- NCT00999778
- Testing
- Caregiver-Mediated Intervention, Caregiver-Education Intervention
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Reading Disability, Anxiety
Evidence-Based Interventions to Enhance Outcomes Among Struggling Readers
Despite decades of research on reading disabilities, little is known about improving reading in the middle grades (i.e., grades 3-6) and advancements have been hindered by the narrow focus on reading problems alone without…
- Trial name
- NCT04059939
- Testing
- Reading, Anxiety Management, Classroom Business as Usual
- Where
- United States
- Volunteers
- 542 people
- Sponsor
- Boston University Charles River Campus
Preterm
Preschool Outcomes of a Previous RCT - ReDiMOM (NCT04540575)
This study will evaluate neurodevelopmental, health, and economic outcomes in preschool children born very preterm that participated in a randomized trial of an economic intervention designed to increase breastmilk feedings while…
- Trial name
- NCT07702357
- Testing
- This is a an observational prospective cohort study of a previous interventional trial (NCT04540575)
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Rush University Medical Center
Attention Deficit Hyperactivity Disorder
Efficacy of Cognitive Behavioral Therapy in Treatment of Adults With Attention Deficit Hyperactivity Disorder
The purpose of the project is to evaluate the efficacy of cognitive behavioral therapy (CBT) for adults with attention deficit hyperactivity disorder (ADHD) with and without stimulant medication and compare it to medication…
- Trial name
- NCT02210728
- Testing
- methylphenidate or amphetamine product, Cognitive behavioral therapy
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Lily Hechtman
Autism
Acuity Functional Impact and Implementation Outcomes Evaluation
This study will test feature enhancements to a behavioral therapy data collection software (Motivity) that will add a new clinical decision support module, called Acuity.
- Trial name
- NCT06561581
- Testing
- Acuity
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Experiad LLC
Development Delay, Development, Child
The Opening Doors to Early Intervention Study
Poor urban minority children often experience delays in their early development leading to health disparities. Publicly funded early intervention services are available to improve child development among these children in…
- Trial name
- ODEI (NCT03625115)
- Testing
- Family Navigator (FN)
- Where
- United States
- Volunteers
- 357 people
- Sponsor
- Children's Hospital of Philadelphia
Premature Birth
US and Neurodevelopmental Outcomes in the Neonatal Intensive Care Unit (NICU)
The objective of the project is to identify clinical factors (nutritional and non-nutritional) which are associated with ultrasound measurements of muscle and adipose tissue and to determine whether these ultrasound measurements…
- Trial name
- NCT05071508
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Minnesota
Attention Deficit Hyperactivity Disorder
Preference and Goal Directed Attention Deficit Hyperactivity Disorder Care- Pilot Study
This pilot intervention study will test the feasibility and acceptability and explore the outcomes of an urban, primary care-based intervention to measure families' preferences and goals for Attention-Deficit/Hyperactivity…
- Trial name
- NCT01487967
- Testing
- Preference and Goal Instrument
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Children's Hospital of Philadelphia
Autism
Autism in Adult Patients and the Effects on Caregivers
Background: The number of adults with autism is expected to rise significantly in the near future, due to two main reasons: First, a dramatic increase in the estimates of the prevalence of autism starting in the mid 1980s…
- Trial name
- NCT00367107
- Where
- Israel
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Hypoplastic Left Heart Syndrome
Near-infrared Spectroscopy (NIRS) Neurodevelopmental Outcomes
We believe that how a baby with Hypoplastic Left Heart Syndrome (HLHS)does after a major open heart operation, measured by things like blood pressure, oxygen saturation, heart rate and others, may have an impact on development.
- Trial name
- NIRS-ND (NCT00464100)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
ADHD, Depression
Pilot Study of the Parental Friendship Coaching+ Program for Families of Children With Attention-deficit/Hyperactivity Disorder
Behavioural parent training (BPT) is a front-line treatment for children with attention-deficit/hyperactivity disorder (ADHD) that teaches parents how to support their child and manage behaviour.
- Trial name
- PFC+ (NCT05333887)
- Testing
- PFC+
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- University of British Columbia
Autism Spectrum Disorder, Autism
Boston Outcomes of Autism in Toddlers Study
The purpose of this research study is to learn more about the outcomes of children who received an Autism Spectrum Disorder (ASD) diagnosis when they were toddlers.
- Trial name
- BOAT (NCT03517163)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Boston Children's Hospital
Autism Spectrum Disorder (ASD)
Supportive Outcomes Through Listening, Validation, and Empowerment
This research aims to pilot an intervention that will provide practitioners and clinicians with evidenced-based behavioral health strategies for working with autistic adults.
- Trial name
- SOLVE (NCT06587594)
- Testing
- Solution Focused Brief Therapy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Texas at Austin
Neurodevelopmental Disorders, Autism Spectrum Disorder
Patterns of Neurodevelopmental Disorders
The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection, Pediatric Acute-Onset Neuropsychiatric Syndrome
- Trial name
- NCT06213090
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Richard Frye
Neurodevelopmental Disorders, Intellectual Disability
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
The goal of this observational study is to learn about the impact of the diabetes drug glibenclamide (glyburide) on neurodevelopment in individuals with iDEND (developmental delay, epilepsy and neonatal diabetes) due to the V59M…
- Conditions
- Neurodevelopmental Disorders, Intellectual Disability, Development Delay, ADHD
- Trial name
- iDEND (NCT05751525)
- Testing
- Sulfonylurea
- Where
- 4 sites in United States, Italy and 2 more
- Volunteers
- 21 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Concussion, Mild, Post Concussion Symptoms
RTL Concussion Communication
This study is aimed at improving health outcomes for adolescents who sustain sport and recreation related concussions (SRRC) by enhancing Return to Learn (RTL).
- Conditions
- Concussion, Mild, Post Concussion Symptoms, Cognitive Impairments, Cognitive Impairments, Mild
- Trial name
- NCT06212726
- Testing
- InjureFree
- Sponsor
- University of Florida
Alcoholism, Attention Deficit Disorder With Hyperactivity
ADHD: Gaps Between Patients With Alcohol-dependence and Impact on Relapse
Some recent studies have found that adult attention deficit - hyperactivity disorder (ADHD) was frequent among patients with alcohol-dependence.
- Trial name
- AGADIR (NCT02364817)
- Testing
- cognitive and psychiatric assessment
- Where
- 3 sites in France
- Volunteers
- 113 people
- Sponsor
- University Hospital, Lille