Clinical trials: Neurodevelopmental Disorders
Intellectual Disability
The Feldenkrais Method for People With Intellectual Disability
Loss of functioning and age-related health problems tend to appear earlier in individuals with intellectual disability (ID) than in their non-disabled peers and due to this people with ID who are in employment tend to need to…
- Trial name
- NCT03203226
- Testing
- FELDENKRAIS METHOD (FM)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Tourette Syndrome, Tic Disorder
Effectiveness of Symptom Management Application on Parental Care Ability of Children With Tourette Syndrome
This study developed a Tourette Syndrome (TS) symptom management application (APP) to improve the care needs, sleep quality, anxiety, quality of life, and parenting relationship of parents of children with Tourette Syndrome.
- Conditions
- Tourette Syndrome, Tic Disorder, Neurodevelopmental Disorder
- Trial name
- NCT06613126
- Testing
- Symptom Management APP group, health education instructions group
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Unilateral Cleft Lip and Palate, Cleft Lip
Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients
The purpose of this study is to evaluate which surgical protocol for treating Unilateral Cleft Lip and Palate (UCLP), a single or two stage repair ( with hard palate late closure) will have less impact in mid facial growth.
- Conditions
- Unilateral Cleft Lip and Palate, Cleft Lip, Cleft Palate, Developmental Disabilities
- Trial name
- NCT02329509
- Testing
- two stage palate surgical repair, One stage Palate Surgical repair
- Volunteers
- 64 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Autistic Disorder
Field Test of Motivity.Net Software for Data Collection During Behavioral Interventions
This is a study funded by a Phase II SBIR to build and test the feasibility of a new software prototype for delivering evidence-based behavioral therapy treatment for autism.
- Trial name
- NCT03919721
- Testing
- Applied Behavioral Analysis
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Experiad LLC
Autism, Autism Spectrum Disorder
Word Learning From Parentese in Autistic Children
The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are…
- Conditions
- Autism, Autism Spectrum Disorder, Neurodevelopmental Disorders
- Trial name
- NCT06649916
- Testing
- Parentese Speech, Adult Registered Speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Autism Spectrum Disorder
Cognitively Enhanced Tai Chi for Executive Function in Children With Autism Spectrum Disorder
This study compares three exercise courses for children aged 8-11 years with autism spectrum disorder: Tai Chi with added cognitive challenges, standard Tai Chi, and general exercise.
- Trial name
- NCT07322952
- Testing
- Cognitively Enhanced Tai Chi, Standard Tai Chi, General Exercise
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Jinan University Guangzhou
Autism Spectrum Disorder
Feasibility and Safety of a Virtual-Reality Based Job Interview Training Tool in Teenagers With High-Functioning Autism
The current project involves the application of a VR job training software. We propose to use an interactive VR job interview practice system, Virtual Reality Job Interview Training (VR-JIT), in youths with ASD at the highschool…
- Trial name
- NCT04773548
- Testing
- VR-JIT
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Congenital Disorders
Retrospective of Children With ADHD and Cardiac Symptoms
There is some evidence suggesting ADHD medication interaction could result in mild myocardial ischemia/infarct.
- Trial name
- NCT00266955
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Healthcare of Atlanta
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Attention Deficit Hyperactivity Disorder
A Within-Subject Cross-Over Comparison Between Immediate Release and Extended Release Adderall
The purpose of this pilot study is to compare Adderall ® and Adderall XR ® in terms of their effectiveness and side effects for the treatment of ADHD in adults.
- Trial name
- NCT00468143
- Testing
- Adderall ® Immediate Release, Adderall XR ®
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- NYU Langone Health
Intellectual Disability
A Computer-based Cognitive Remediation Program for Adults With Intellectual Disability
Adults with intellectual disabilities have great difficulty in adapting to social situations and relationships. Cognitive impairment associated with intellectual disability are important factors to understand their difficulties…
- Trial name
- REHABILITUS (NCT04025398)
- Testing
- Cognitive remediation program, Control group
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Hôpital le Vinatier
Autism Spectrum Disorder
Efficacy and Mechanism of rTMS in Children With ASD: an Open-label Clinical Trial
This study is a 6-week open-label clinical trial involving 20 children aged 6-10 years with autism spectrum disorder. During the study, subjects received repeated transcranial magnetic stimulation（rTMS）intervention at the left…
- Trial name
- NCT05238298
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
ADHD
Focused Ultrasound for the Treatment of ADHD Symptoms
The purpose of this open label study is to evaluate longer term tolerability and potential effectiveness of transcranial ultrasound in people with attention deficit hyperactive disorder (ADHD).
- Trial name
- NCT04497363
- Testing
- Brainsonix Pulsar 1002
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Neurological Associates of West Los Angeles
Toe Walking Behaviors, Backward Walking
Backward Walking Effects on Toe Walking in a Child With ASD: Single-Case Study
This study tested the hypothesis that backward walking exercises can reduce Toe Walking Behaviors (TWB) in children with ASD and emphasized the importance of pedobarographic measurements for quantitative TWB assessment.
- Trial name
- NCT07078214
- Testing
- Foot Sole Surface Area Measurements, Walking Exercise Program and Implementation Process
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people
- Sponsor
- Giresun University
Attention Deficit Hyperactivity Disorder
Methylphenidate Study in Young Children With Developmental Disorders
The purpose of this study is to determine if methylphenidate (a common brand name is Ritalin), a medicine used for treating older children with Attention Deficit and Hyperactivity Disorder (ADHD), is also safe and helpful for…
- Trial name
- NCT00517504
- Testing
- Methylphenidate
- Volunteers
- 48 people
- Sponsor
- University of Arizona
Autism Spectrum Disorder
Effects of Low Frequency Whole Body Vibrations on Motor Skills and Sensory Integration in Children With Autism
This randomized controlled trial aims to evaluate the efficacy of low-frequency Whole Body Vibration therapy on motor skills and sensory integration in children aged 5-9 years diagnosed with mild to moderate ASD.
- Trial name
- NCT07757035
- Testing
- whole body vibration, Routine physical therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Global Developmental Delay
Design and Implementation of a Carer Aromatherapy Training (CAT) Program for Children With Global Developmental Delay in Hong Kong: A Mixed Qualitative Study Using the COM-B Framework
This project aims to design and implement a Carer Aromatherapy Training (CAT) program, guided by the Capability, Opportunity, Motivation and Behaviour (COM-B) model, to empower carers with safe and effective aromatherapy…
- Trial name
- CAT programme (NCT07800689)
- Testing
- Carer Aromatherapy Training (CAT) program and home massage with massage oil with the mixture of Petitgrain Mandarin (Citrus reticulate) essential oil and fractionated coconut oil
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hong Kong Metropolitan University
ADHD
Safety and Efficacy of SPD489 in Adolescent Subjects Aged 13-17 Years With Attention-Deficit/Hyperactivity Disorder (ADHD)
The primary objective of the study is to evaluate the efficacy of SPD489 compared to placebo in adolescent subjects (13-17 years of age inclusive) with ADHD in the analog classroom setting based on the Permanent Product Measure…
- Trial name
- NCT01274221
- Testing
- SPD489
- Where
- 6 sites in United States
- Sponsor
- Shire
Attention Deficit Disorder With Hyperactivity
Tocotrienols for School-going Children With ADHD
The purpose of this study is to determine if tocotrienol supplementation given to school going children with ADHD will result in reduction of their ADHD symptoms.
- Trial name
- TOCAT (NCT01855984)
- Testing
- Oral mixed tocotrienols
- Where
- Malaysia
- Volunteers
- 160 people
- Sponsor
- RCSI & UCD Malaysia Campus
Tourette Syndrome
Sensory Symptoms in Tourette Syndrome
Patients with tics will be asked to complete a series of validated questionnaires (in electronic and/or paper format) regarding symptoms and conditions often associated with Tourette syndrome, including premonitory urges, sensory…
- Trial name
- SenST (NCT03851484)
- Where
- 2 sites in United States
- Volunteers
- 214 people
- Sponsor
- Vanderbilt University Medical Center