Clinical trials: Neurodevelopmental Disorders
Developmental Coordination Disorder
Taping for Children With and Without Movement Clumsiness
To investigate the effects of K Tape on walking pattern, muscle activity and motor performance in children with and without developmental coordination disorder (DCD).
- Trial name
- NCT02945124
- Testing
- K tape
- Where
- Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Autism Spectrum Disorder, Nonverbal Communication
Exploring Predictors of Response to a Peer-Mediated Intervention for Preschoolers With ASD
This study will examine what child variables (i.e., social attention and peer interest) predict communication gains in response to a peer-mediated intervention for 40 minimally-verbal preschool children with ASD and 80 peers.
- Trial name
- NCT05277103
- Testing
- Exploring predictors of response to a peer-mediated communication intervention for minimally verbal preschoolers with ASD
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Attention Deficit Hyperactivity Disorder (ADHD), Deficient Emotional Self-Regulation (DESR)
Omega-3 Fatty Acid Supplementation to ADHD Pharmacotherapy in ADHD Adults With Deficient Emotional Self-Regulation Traits
The purpose of this study is to a) assess the efficacy of omega-3 fatty acids in the treatment of Deficient Emotional Self-Regulation (DESR) among stimulant treated Attention Deficit Hyperactivity Disorder (ADHD) adults, b)…
- Trial name
- NCT01399827
- Testing
- ADHD Medication, Omega-3 Fatty Acids
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Massachusetts General Hospital
ADHD
Classroom Behavior Support (CBS) Project
The goal of the study is to conduct a randomized clinical trial to evaluate the impact of the Classroom Behavior Support Program (CBS; a multi-component, individually-tailored teacher consultation program) on teachers' classroom…
- Trial name
- CBS (NCT05137327)
- Testing
- Classroom Behavior Support (CBS) Condition, Standard Problem Solving Consultation
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Ohio University
ADHD
Functional MRI of Relaxation Response Training in Adults With Attention-Deficit/Hyperactivity Disorder
This research study is being done to examine how meditation and the relaxation response (RR) may change brain activity in attention-deficit/hyperactivity disorder (ADHD).
- Trial name
- ADHD (NCT01404273)
- Testing
- Meditation/Relaxation Response Training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
Attention Deficit Hyperactivity Disorder (ADHD)
Safety and Tolerability Study of SHP465 in Children Aged 4 to 12 Years Diagnosed With Attention-deficit/Hyperactivity Disorder (ADHD)
The purpose of the study is to evaluate the long-term safety and tolerability of SHP465 at 6.25 milligram (mg) in children aged 4 to 12 years diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT03325894
- Testing
- SHP465
- Where
- 48 sites in United States
- Volunteers
- 141 people
- Sponsor
- Shire
Aphasia, Stroke
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
The purpose of this study is to assess changes in language abilities of participants with chronic, post-stroke aphasia following an 8-week therapy period combined with brain stimulation.
- Trial name
- NCT04142866
- Testing
- Anodal transcranial direct current stimulation, Speech-Language Therapy (SLT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- City University of New York
Tourette Syndrome
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder
OBJECTIVES: I. Evaluate the safety and efficacy of the alpha-2 adrenergic agonist guanfacine in children and adolescents with Tourette syndrome or other chronic tic disorder, and attention deficit hyperactivity disorder.
- Trial name
- NCT00004376
- Testing
- guanfacine
- Volunteers
- 35 people
- Sponsor
- National Center for Research Resources (NCRR)
Autism Spectrum Disorder, Anxiety
The Effects of Exercise in Anxiety in Children With ASD
This study will examine the effects of a school based exercise programme on anxiety and behaviour levels in children with autism.
- Conditions
- Autism Spectrum Disorder, Anxiety, Behavior
- Trial name
- NCT03860389
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- South East Technological University
Neurodevelopmental Disorders
Long-term Consequences of Admission for Pediatric Intensive Care Before One Year of Age
This study is a retrospective cohort study. The PICU children will include all surviving children who were admitted to the PICU of Copenhagen University Hospital between 1st of January 2002 and 31st of December 2016.
- Trial name
- NCT04562935
- Testing
- admission to pediatric intensive care with mechanical ventilation
- Where
- Denmark
- Volunteers
- 330 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Autism, Job Interview Performance
Using ChatGPT as a Job Coach for Adults With Autism Spectrum Disorder
The goal of this clinical trial is to examine the effectiveness of the ChatGPT-based job coach in helping ASD individuals prepare for job application, job interview, and interpersonal skills in workplaces.
- Trial name
- NCT06816589
- Testing
- ChatGPT-based job coaching
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Attention Deficit Hyperactivity Disorder
Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) With Atomoxetine in Young Adults and Its Effects on Functional Outcomes
This study will evaluate atomoxetine's efficacy in treating attention-deficit/hyperactivity disorder (ADHD) symptoms and atomoxetine's effect on functional outcomes in young adults.
- Trial name
- NCT00510276
- Testing
- Atomoxetine hydrochloride
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 445 people
- Sponsor
- Eli Lilly and Company
Obsessive-Compulsive Disorder, Anxiety Disorders
Treatment for Anxiety in Children
The purpose of this study is to see if it is effective to treat children with anxiety disorders with fluvoxamine. Fluvoxamine has been successfully used to treat obsessive-compulsive disorder (OCD) in adults and children.
- Conditions
- Obsessive-Compulsive Disorder, Anxiety Disorders, Generalized Anxiety Disorder, Social Phobia
- Trial name
- NCT00000389
- Testing
- Fluvoxamine
- Sponsor
- National Institute of Mental Health (NIMH)
Autism Spectrum Disorder
Assessing the Impact of Probiotic Supplementation in Children Diagnosed With Autism Spectrum Disorder: the PROBI-O-TISM Study
Children with autism spectrum disorder (ASD) present with stereotyped behaviors and often with comorbidities including gastrointestinal symptoms and sleep disturbances.
- Trial name
- (PROBI-O-TISM) (NCT06906068)
- Testing
- Three strains of Lactobacillus: L. acidophilus CL1285®, L. casei LBC80R® and L. rhamnosus CLR2®
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Valérie Marcil
Attention Deficit Disorder With or Without Hyperactivity (ADHD), Autism Spectrum Disorder (ASD)
Characterize the Links Between Sleep, Emotional Dysregulation and Learning in Neurodevelopmental Disorders.
The aim of this protocol is to disentangle the links between symptoms of emotion dysregulation, sleep disorders and cognitive deficits by measuring the effects of an emotional induction task on childrens' sleep with autism…
- Trial name
- SOM-EMO-TND (NCT06479668)
- Testing
- Trier Social Stress Task
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Stress
Parent Supports Intervention Project
The purpose of this study is to evaluate the impact of two community based interventions for parents of adults with intellectual or developmental disabilities (IDD) who are requesting services.
- Trial name
- NCT01981070
- Testing
- Mindfulness Intervention for Parents, Support and Information for Parents
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Autism Spectrum Disorder
Development and Evaluation of a Parent-led Intervention Module for Early Autism Spectrum Disorder (PRIME-ASD) in Odisha, India: Protocol for a Multiphase Mixed-methods Study Including an Open-label Randomised Controlled Trial
Many families of young children with autism in India wait a long time for a diagnosis and specialist therapy, and receive little structured guidance on how to help their child at home.
- Trial name
- NCT07858383
- Testing
- Behavioral: PRIME-ASD (Parent-led Intervention Module for Early Autism Spectrum Disorder), Behavioral: PRIME-ASD; Other: Treatment as usual
- Volunteers
- 188 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Autism Spectrum Disorder
A Study of RG7314 to Investigate Efficacy and Safety in Individuals With Autism Spectrum Disorders (ASD)
This multi-center, randomized, double-blind, parallel group, placebo-controlled, proof of concept study will investigate the efficacy and safety of RG7314 in adult participants with ASD.
- Trial name
- NCT01793441
- Testing
- RG7314
- Where
- 56 sites in United States
- Volunteers
- 223 people
- Sponsor
- Hoffmann-La Roche
Attention Deficit Disorder With Hyperactivity
NeuroLex EEG-Based ADHD Assessment Aid, Pivotal Study
The study will evaluate the effectiveness of a standardized EEG method with the intended clinical users in the intended clinical settings with the intended population (patients who would typically receive a clinician's evaluation…
- Trial name
- NEBA (NCT00595751)
- Where
- 10 sites in United States
- Volunteers
- 300 people
- Sponsor
- Lexicor Medical Technology, LLC
Autism Spectrum Disorder
Effectiveness of Social Skills Training Group for Children With Autism Spectrum Disorder
Socio-communicative impairments are core deficits in individuals with autism spectrum disorder (ASD). Individuals with ASD have difficulty understanding eye contact, facial expressions, body language, and different tones of voice…
- Trial name
- NCT04551313
- Testing
- social skill group
- Where
- 2 sites in Taiwan
- Volunteers
- 86 people
- Sponsor
- National Taiwan University Hospital