Clinical trials: Neurodevelopmental Disorder (Diagnosis)
Autism Spectrum Disorder (ASD), Pain Perception
Quantitative Sensory Testing to Study Pain Perception in Autism
This study aims at assess sensory perception, and pain perception, in neurodivergent children and adolescent in the autism spectrum.
- Trial name
- PPiA (NCT06659731)
- Testing
- Quantitative Sensory testing (QST), EEG
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Autism Spectrum Disorder
Safety, Tolerability and Pharmacokinetics of Lumateperone in Pediatric Patients With Autism Spectrum Disorder
Study ITI-007-035 is a Phase 1b, multicenter, open-label study to evaluate the safety, tolerability, and PK of lumateperone for pediatric patients with Autism Spectrum Disorder.
- Trial name
- NCT06557902
- Testing
- Lumateperone 10.5 mg capsule, Lumateperone 21 mg capsule, Lumateperone 5 mg ODT
- Where
- 7 sites in United States
- Volunteers
- 33 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Mild Cognitive Impairment, Alzheimer's Disease
Assess the Prognostic Usefulness of Flutemetamol (18F) Injection for Identifying Subjects With Amnestic Mild Cognitive Impairment Who Will Convert to Clinically Probable Alzheimer's Disease
This study will investigate the efficacy of the Flutemetamol (18F) Injection PET tracer in identifying abnormal (18F) flutemetamol uptake patterns which predict the conversion from aMCI to a b-amyloid associated clinically…
- Trial name
- NCT01028053
- Testing
- Flutemetamol (18F) Injection
- Where
- United States
- Volunteers
- 365 people
- Sponsor
- GE Healthcare
Development
Neurodevelopmental Outcomes of Preterm Infants Treated for Pain Management With Repeated Doses of Sucrose 24%
The purpose of this study is to determine the effect of sucrose 24% for pain prevention on preterm infants. Our hypothesis is that repeated doses of sucrose 24%, given prior to painful procedure,do not impair neurodevelopmental…
- Trial name
- NCT01742520
- Testing
- multiple doses of sucrose, Formula or breast milk
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Psychopathic Personality Trait, Conduct Disorder
The Efficacy of a Compassion Focused Therapy-based Intervention in Detained Youth
This non-randomized controlled trial with a control group aimed to assess the efficacy of a 20-session individualized Compassion Focused Therapy-based intervention, the PSYCHOPATHY.COMP, in reducing psychopathic traits (primary…
- Conditions
- Psychopathic Personality Trait, Conduct Disorder, Delinquency
- Trial name
- PSYCOMP (NCT03971682)
- Testing
- PSYCHOPATHY.COMP program., Treatment As Usual - TAU
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Tic Disorder, Childhood, Comorbidities and Coexisting Conditions
Improving Symptom Trajectories of Tic Disorders and Co-occurring Diagnoses: The Role of Integrative Intensive Intervention
The purpose to the current study was to examine the efficacy of a telehealth, group-based, combined and intensive intervention for youth with tic disorders (TDs) and common co-occurring diagnoses.
- Trial name
- NCT04878302
- Testing
- Combination of Comprehensive Behavioral Intervention for Tics (CBIT) and Evidence-based interventions for co-occurring diagnoses (i.e., Cognitive Behavioral Therapy, Behavioral Parent Training)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Florida International University
Attention Deficit Hyperactivity Disorder
STAND Community Trial
The proposed study evaluates the effectiveness of a family-based psychosocial treatment program for teens with ADHD (Supporting Teens' Academic Needs Daily; STAND) developed to be delivered in community settings.
- Trial name
- STAND (NCT02694939)
- Testing
- STAND (Behavior Therapy + Motivational Interviewing), Usual Care
- Where
- United States
- Volunteers
- 278 people
- Sponsor
- Florida International University
Bronchopulmonary Dysplasia, Chronic Lung Disease
Neurotrophin Expression in Infants as a Predictor of Respiratory and Neurodevelopmental Outcomes
Important developmental processes continue until the completion of 40 weeks gestation. Even during fetal life, intrinsic and environmental factors determine the balance between health and the onset and development of diseases.
- Trial name
- NCT03373539
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
Preterm Birth, Development Delay
Evaluation of Digital Follow up of Preterm Infants
The aim is to study how a digital follow up tool can identify the preterm born children and their families who need further support or clinical interventions
- Conditions
- Preterm Birth, Development Delay, Sensory Disorder, Growth Disorders
- Trial name
- ePIPARI (NCT05238168)
- Testing
- ePIPARI digital follow up tool
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- Turku University Hospital
ADHD
Adult Normative Performance of the Quotient ADHD System
This study is being conducted to enhance and extend the clinical utility of the Quotient® ADHD System Adolescent and Adult Version Test by adding large numbers of well-screened controls to the existing Quotient® ADHD System…
- Trial name
- ADHD (NCT01308450)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- BioBehavioral Diagnostics Company
Attention Deficit Hyperactivity Disorder (ADHD)
Effectiveness of Methylphenidate Late Formula to Reduce Cannabis Use in Young Cannabis-Related Patients and Attention Deficit Disorder Hyperactivity
Abuse of psychoactive substances is a behavior belonging to the field of risk behaviors that begins and takes place during adolescence. These risk behaviors are a major public health problem in France and worldwide.
- Trial name
- METHACAN (NCT03481959)
- Testing
- Methylphenidate
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Attention Deficit Hyperactivity Disorder, Healthy
The Effects of EPA/DHA Supplementation on Cognitive Control in Children With ADHD
Forty children with and 40 children without Attention deficit Hyperactivity Disorder (ADHD) receive Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA) or placebo via a dietary intervention.
- Trial name
- NCT01554462
- Testing
- Eicosapentaenoic acid / Docosahexaenoic acid
- Where
- Netherlands
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Attention Deficit Hyperactivity Disorder
A Longitudinal Follow-up Study of Neuroimage and Neuropsychological Endophenotype Study on ADHD
Attention deficit/hyperactivity disorder (ADHD) is a common (3-10%), early-onset, clinically and genetically heterogeneous neuropsychiatric disorder with lifelong neuropsychological deficits.
- Trial name
- NCT03679403
- Testing
- Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 293 people
- Sponsor
- National Taiwan University Hospital
ADHD
Combined Cognitive Remediation and Behavioral Intervention for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)
The objective of this study is to evaluate a novel sequenced combination of a promising, computerized cognitive training program targeting working memory (WM) deficits in children with attention-deficit/hyperactivity disorder…
- Trial name
- NCT01137318
- Testing
- Cognitive remediation and Parent Training
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Queens College, The City University of New York
Autism Spectrum Disorder, Autism
Group Social ABCs: Early Intervention for Toddlers With Suspected ASD
The Social ABCs is an evidence-based, developmentally informed, caregiver-mediated behavioural intervention for toddlers with suspected or confirmed Autism Spectrum Disorder (ASD).
- Trial name
- NCT03499262
- Testing
- Group Social ABCs
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Psychopathic Personality Trait
Can Psychopathy be Prevented? Clinical, Neuroimaging and Genetic Data
The goal of this clinical trial was to learn about the effect of maltreatment on psychological and brain characteristics in a group of children.
- Trial name
- NCT06028620
- Testing
- Trauma Focused-Cognitive Behavior Therapy
- Where
- Mexico
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Sleep Disorders, Neurodevelopmental Disorder
Study of the Efficacy and Safety of NPC-15 for Sleep Disorders of Children With Neurodevelopmental Disorders
The purpose of this study is to evaluate the efficacy on sleep latency with electronic sleep diaries and the safety of NPC-15.
- Trial name
- NPC-15-6 (NCT02757079)
- Testing
- NPC-15
- Volunteers
- 99 people
- Sponsor
- Nobelpharma
Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder
Study of the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents
Open-label Study to Investigate the Pharmacokinetics and Safety of Tasimelteon in Children and Adolescents.
- Conditions
- Circadian Rhythm Sleep Disorders, Non-24 Hour Sleep-Wake Disorder, Autism Spectrum Disorder, Smith-Magenis Syndrome
- Trial name
- NCT02776215
- Testing
- tasimelteon
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanda Pharmaceuticals
Obsessive Compulsive Disorder, Healthy
Cortical Excitability in Obsessive-Compulsive and Related Disorders
This study will use transcranial magnetic stimulation (TMS) to study the function of the cerebral cortex (outer layer of the brain) in people with obsessive compulsive disorder (OCD) and related disorders.
- Trial name
- NCT00029068
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Anxiety, Autism Spectrum Disorder
Aromatherapy for Anxiety Among Children With Autism Spectrum Disorder
This study evaluated the use of bergamot aromatherapy in the treatment of anxiety in a medical office setting among children who are diagnosed with an autism spectrum disorder. H
- Trial name
- NCT03818490
- Testing
- Bergamot Aromatherapy
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
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