Clinical trials: Nerve Palsy
Bell's Palsy, Facial Nerve Paresis
Intratympanic Steroid for Bell's Palsy
Facial nerve paralysis is due to inflammation around the facial nerve. Current treatment for facial nerve paralysis is a 10 day course of oral steroids (which will reduce the inflammation), with electrodiagnostic testing.
- Trial name
- NCT03508440
- Testing
- Intratympanic injection, Prednisone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Missouri-Columbia
Synkinesis, Facial Nerve Palsy
Efficacy of Topical Apraclonidine for the Treatment of Ocular Synkinesis
The purpose of this study is to determine efficacy of apraclonidine for patients with ocular synkinesis, who are seen in the UAB Facial Nerve Clinic.
- Trial name
- NCT05167760
- Testing
- Apraclonidine
- Sponsor
- University of Alabama at Birmingham
Facial Nerve Paresis
Functional Electrical Stimulation for Facial Muscles
Partial or complete facial paralysis is the weakness of muscles of facial expression. Facial paralysis causes physical, social and emotional problems.
- Trial name
- NCT04457492
- Testing
- Application of FES to the Face
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University Health Network, Toronto
Facial Nerve Palsy
Blink Restoration in Patients With Facial Nerve Palsy
This study is a non-blinded single armed pilot study aiming to apply a newly created medical device in patients with seventh nerve palsy suffering from lagophthalmus in order to determine the best way for neuromuscular…
- Trial name
- NEURO-BLINK (NCT05504473)
- Testing
- NEURO-BLINK Device
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Kantonsspital Aarau
Recurrent Laryngeal Nerve Palsy, Postoperative Dysphonia
Post Thyroidectomy Echographic Method for Study of Vocal Fold Motion
One of the major risks of endocrine surgery is recurrent nerve palsy (RNP), leading to vocal folds (VF) immobility. It happens in 5% of cases, leading to high morbidity: dysphonia, aspirations, impossibility to work.
- Trial name
- VOCALE (NCT03976011)
- Testing
- Transcutaneous Laryngeal Ultrasonography
- Where
- 5 sites in France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia, Local, Phrenic Nerve Paralysis
Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade
One of the most frequently performed peripheral nerve blocks (the injection of local anesthetic near nerves to block sensation/ movement to a specific part of the body) is the interscalene brachial plexus block for upper…
- Conditions
- Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Phrenic Nerve Palsy on the Left
- Trial name
- NCT03677778
- Testing
- Normal saline injected via interscalene nerve catheter
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Stanford University
Cubital Tunnel Syndrome, Ulnar Nerve Compression
Randomized Trial of Supercharged End-to-Side Anterior Interosseous Nerve Transfer for Severe Cubital Tunnel Syndrome
Functional motor recovery distal to a peripheral nerve lesion is predicated upon time to reinnervation of the motor end plate and the number of regenerate axons that reach the target.
- Conditions
- Cubital Tunnel Syndrome, Ulnar Nerve Compression, Ulnar Nerve Palsy, Ulnar Nerve Entrapment
- Trial name
- NCT04647058
- Testing
- Cubital tunnel release, Supercharged end-to-side (SETS) nerve transfer
- Where
- 2 sites in United States
- Sponsor
- Brigham and Women's Hospital
Stroke, Spinal Cord Injuries
User Satisfaction of Customised 3D Printed Ankle-Foot Orthosis in Comparison to Thermoformed Ankle-Foot Orthosis for Patients With Neurological Conditions: A Preliminary Study
Study Design and Subject Recruitment: This was a cross-sectional study in a single centre outpatient setting at the Foot Care and Limb Design Centre, Tan Tock Seng Hospital.
- Conditions
- Stroke, Spinal Cord Injuries, Nerve Palsy
- Trial name
- NCT05122949
- Testing
- 3D Printed Ankle-Foot Orthosis, Thermoformed Ankle-Foot Orthosis
- Where
- Singapore
- Volunteers
- 5 people
- Sponsor
- Tan Tock Seng Hospital
Superior Oblique Palsy
Inferior Oblique Myectomy Versus Anterior and Nasal Transposition of Its Tendon for Treatment of Superior Oblique Muscle Palsy
This Study aims at comparing the safety and efficacy of inferior oblique myectomy to anterior and nasal transposition of inferior oblique as two treatment options of superior oblique palsy regarding ocular alignment …
- Trial name
- NCT05031312
- Testing
- inferior oblique weakening
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Facial Nerve Palsy, Bell's Palsy
Electro Physiological Responses to Kabat Motor Control Re-education on Bell's Palsy: A Randomized Controlled Study
To investigate the Effect of Kabat motor control re-education therapy on facial nerve Electro physiological responses and facial muscles function in bell's palsy.
- Trial name
- NCT04894513
- Testing
- Kabat motor control re-education therapy, conventional selected program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Lama Saad El-Din Mahmoud
Recurrent Laryngeal Nerve Palsy, Risk Factors of Vocal Cord Palsy
Predisection Risk Factors for Vocal Cord Palsy After Total Thyroid Surgery
In patients undergoing total thyroidectomy, intraoperative nerve monitoring according to the International Standards Guideline Statement may detect nerves more susceptible to injury.
- Conditions
- Recurrent Laryngeal Nerve Palsy, Risk Factors of Vocal Cord Palsy, Neuromonitoring in Thyroid Surgery
- Trial name
- NCT04986592
- Volunteers
- 106 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Phrenic Nerve Palsy
Does Saline Injection Around Phrenic Nerve Reduce Incidence of Diaphragmatic Paresis Following Interscalene Block?
Hemi-diaphragmatic palsy is a common undesirable effect of interscalene block, with an incidence of up to 100%. Mechanism of palsy is thought to be related to spread of local anaesthetic anterior to the anterior scalene muscle.
- Trial name
- NCT02893228
- Testing
- Saline, Levobupivacaine
- Where
- Ireland
- Volunteers
- 36 people
- Sponsor
- The Adelaide and Meath Hospital, incorporating The National Children's Hospital
Parkinson Disease, Parkinsonism
More Than a Movement Disorder: Applying Palliative Care to Parkinson's Disease
This is a two-center (University of Colorado, University of California San Francisco) community-based comparative effectiveness study of outpatient palliative care for Parkinson's disease (PD) and related disorders (progressive…
- Conditions
- Parkinson Disease, Parkinsonism, Lewy Body Disease, Supranuclear Palsy, Progressive
- Trial name
- MTMD (NCT03076671)
- Testing
- Palliative Care
- Where
- 2 sites in United States
- Volunteers
- 783 people
- Sponsor
- University of Colorado, Denver
Muscle Injury, Nerve Injury
Extramembranous and Interosseous Technique of Tibialis Posterior Tendon Transfer
Foot drop deformity is a life limiting condition characterized by loss of ankle dorsiflexion and eversion. Main condition leading to drop foot condition include irrecoverable muscle and nerve injuries, poliomyelitis, drug…
- Conditions
- Muscle Injury, Nerve Injury, Poliomyelitis, Leprosy
- Trial name
- NCT01751503
- Testing
- Interosseous route of TPTT, Extra membranous route of TPTT
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Iva Hauptmannova
Peripheral Nerve Disease, Peripheral Nerve Injury Lower Limb
Effect of Ankle-foot Orthoses on Balance Confidence
The patients at our Prosthetics and Orthotics Outpatient Clinic who have had an ankle-foot orthosis for at least one year will fill in the Activities-Specific Balance Confidence Scale (ABC Scale) for wearing the orthosis and for…
- Conditions
- Peripheral Nerve Disease, Peripheral Nerve Injury Lower Limb, Poliomyelitis, Cerebral Palsy
- Trial name
- ABCOGS (NCT04080687)
- Testing
- Ankle-foot orthosis
- Where
- Slovenia
- Volunteers
- 150 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Phrenic Nerve Palsy
Phrenic Nerve Injury During Pulmonary Vein Isolation With the Second-generation Cryoballoon.
To determine the most frequent complication associated with cryoballoon PVI. The main hypothesis is to explore the incidence of phrenic nerve palsy.
- Trial name
- YETI-Registry (NCT03645577)
- Where
- Germany
- Volunteers
- 731 people
- Sponsor
- University of Luebeck
Facial Nerve Palsy
Facial Function Reanimation by Electrical Pacing in Unilateral Facial Paralysis.
Purpose of the trial is to study the activations of paralyzed facial muscles in a unilateral facial nerve palsy with a multi-channel electrical stimulator.
- Trial name
- NCT03496025
- Testing
- Electrical muscle stimulation
- Where
- Finland
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Facial Nerve Palsy
Collagen Treatment in Facial Nerve Palsy
To test the effectiveness of a collagen-based treatment for patients complaining of long standing facial nerve axonotmesis, who are following a proprioceptive neuromuscular facilitation protocol (Kabat method), compared to a…
- Trial name
- NCT04353908
- Testing
- Rehabilitation, Collagen Injection
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Uniter Onlus
Encephalitis, Myelitis
Neurologic Manifestations of the Arbovirus Infection in Colombia
This is a multi-center case-control study that aims to define the association between the exposure to an arbovirus infection and the development of a neurological syndrome in patients from Colombia.
- Conditions
- Encephalitis, Myelitis, Guillain-Barre Syndrome, Cranial Nerve Palsies
- Trial name
- NCT03206541
- Where
- 8 sites in Colombia
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Nerve Injury, Nerve Palsy
Deltoid Muscle Contribution to Shoulder Function
There is only one study in the literature about the quantitative effect of M. deltoideus on the movement of the shoulder. Here, the author described a 35-80% loss of abduction power after selective blockade of the N. axillaris.
- Trial name
- NCT03881462
- Testing
- Axillary nerve block for artificial deltoid muscle palsy
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital