Clinical trials: Neovascular Age Related Macular Degeneration
Neovascular Age Related Macular Degeneration
Safety and Tolerability of Intravitreal VEGF Trap Formulations in Subjects With Neovacular AMD
To assess the safety and tolerability of repeated intravitreal (ITV) administration of VEGF Trap.
- Trial name
- NCT00383370
- Testing
- VEGF Trap
- Where
- 6 sites in United States
- Volunteers
- 20 people
- Sponsor
- Regeneron Pharmaceuticals
Macular Degeneration, Age-related Macular Degeneration
Observational Study Of The Long-Term Effect Of Macugen In Patients With Wet Age-Related Macular Degeneration
Long-term observational study to assess the safety, efficacy and quality of life of patients with neovascular age-related macular degeneration (AMD) under Macugen treatment.
- Conditions
- Macular Degeneration, Age-related Macular Degeneration, Neovascular Macular Degeneration
- Trial name
- MACULA (NCT01245387)
- Testing
- Pegaptanib
- Volunteers
- 1,001 people
- Sponsor
- Pfizer
Neovascular Age Related Macular Degeneration
Efficacy and Safety Study of Lucentis (Ranibizumab) and Visudyne (Verteporfin) Combination Therapy in Neovascular AMD
This study is designed to evaluate the effect of Visudyne® combination therapy (Visudyne® [verteporfin for injection] and Lucentis™) on visual acuity outcomes.
- Trial name
- Luvi (NCT00574093)
- Testing
- Ranibizumab; Verteporfin
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione G.B. Bietti, IRCCS
Age-Related Neovascular Macular Degeneration
Prevention of Vision Loss in Patients With Age-Related Macular Degeneration (AMD) by Intravitreal Injection of Bevacizumab and Ranibizumab
The study is designed to demonstrate the therapeutic non-inferiority of the recombinant humanized monoclonal VEGF antibody bevacizumab administered by intravitreal injection in the treatment of AMD in comparison to the related…
- Trial name
- VIBERA (NCT00559715)
- Testing
- bevacizumab, ranibizumab
- Where
- Germany
- Volunteers
- 366 people
- Sponsor
- Klinikum Bremen-Mitte, gGmbH
Neovascular Age-Related Macular Degeneration
Intravitreal Bevacizumab vs. Bevacizumab Combined With Triamcinolone for Neovascular AMD
To compare the efficacy and safety results of intravitreal bevacizumab alone with bevacizumab + triamcinolone acetonide in neovascular AMD.
- Trial name
- NCT00370370
- Testing
- bevacizumab, bevacizumab + triamcinolone acetonide
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Neovascular Age Related Macular Degeneration
The Effects of Bevacizumab and Ranibizumab on Ocular Pulse Amplitude in Neovascular Age Related Macular Degeneration (AMD)
One concern about repeated intravitreal injections of bevacizumab (Avastin) and ranibizumab (Lucentis) in wet age related macular degeneration, is that in addition to blocking the proteins that triggers the development and…
- Trial name
- AMD (NCT00640640)
- Testing
- Pascal Dynamic Contour Tonometer, Ranibizumab, Bevacizumab
- Where
- 2 sites in Belgium, Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Neovascular Age-Related Macular Degeneration
Combined PDT and Intravitreal Bevacizumab vs Combination of PDT, Intravitreal Bevacizumab and Triamcinolone for Neovascular AMD
To compare the efficacy and safety of photodynamic therapy (PDT) combined with intravitreal bevacizumab versus combination of photodynamic therapy , intravitreal bevacizumab and intravitreal triamcinolone for neovascular AMD.
- Trial name
- NCT00370539
- Testing
- verteporfin, bevacizumab, triamcinolone acetonide
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Neovascular Age-Related Macular Degeneration
Prospective OCT Study With Lucentis for Neovascular AMD (PrONTO Study)
The PrONTO Study was designed to evaluate the response of neovascular age-related macular degeneration (AMD) patients to intravitreal Lucentis using Optical Coherence Tomography (OCT) imaging.
- Trial name
- NCT00344227
- Testing
- Lucentis (Ranibizumab)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami