Clinical trials: Neonatal Hyperbilirubinemia
Jaundice, Neonatal, Neonatal Diseases and Abnormalities
Evaluation of Bili-ruler, a Low-cost, Plastic Icterometer for Community-based Screening of Jaundice in Newborns
Newborn jaundice, or accumulation of bilirubin molecules in blood, affects 60-80% of newborns and, in severe cases, places newborns at risk of brain damage and death.
- Conditions
- Jaundice, Neonatal, Neonatal Diseases and Abnormalities, Neonatal Hyperbilirubinemia, Screening Tool
- Trial name
- NCT06687746
- Testing
- Bili-ruler
- Where
- 5 sites in India, Kenya and 2 more
- Volunteers
- 4,060 people, healthy volunteers welcome
- Sponsor
- George Washington University
Prematurity, Low Birth Weight
Paternal Involvement in Nursing Guidance and Breastfeeding Self-Efficacy in Mothers of High-Risk Newborns
This study aims to evaluate whether a structured nursing guidance program that increases fathers' participation in the care of hospitalized high-risk newborns improves maternal outcomes compared with routine nursing care.
- Conditions
- Prematurity, Low Birth Weight, Respiratory Distress Syndrome, Newborn, Neonatal Hyperbilirubinemia
- Trial name
- NCT07834008
- Testing
- step-by-step parent education, active father participation in breastfeeding support
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Anemia, Iron Deficiency
Effect of Timing of Umbilical Cord Clamping on Anaemia at 8 and 12 Months and Later Neurodevelopment
The investigators plan a study to randomize 540 children in Nepal to early (≤30 seconds) or late (≥180 seconds) clamping of the umbilical cord at birth.
- Conditions
- Anemia, Iron Deficiency, Neonatal Jaundice
- Trial name
- NCT02222805
- Testing
- Early (≤30 seconds) cord clamping, Delayed (≤180 seconds) cord clamping
- Where
- Nepal
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Hypercholesterolemia, Hyperbilirubinemia
Study of Efficacy and Safety of the Plasmapheresis Method With Albumin Compensation Compared With the Plasmapheresis Method Without Albumin Compensation for Aging Biomarkers Correction in Men and Women Aged 40 to 55 Years Old
Reaching active aging makes it important to implement new methods affecting the biological age of a person. Biochemical parameters of a blood test are aging biomarkers that are ones of the most accessible for testing.
- Conditions
- Hypercholesterolemia, Hyperbilirubinemia, Hyper IgE Syndrome, Hyper Beta Lipoproteinemia
- Trial name
- NCT04897113
- Testing
- plasma exchange with albumin, plasma exchange without albumin
- Where
- 2 sites in Russia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Rehabilitation and Balneology
Hyperbilirubinemia, Jaundice
Demographic, Metabolic, and Genomic Description of Neonates With Severe Hyperbilirubinemia
The purpose of this study is to compare the demographic, metabolic, and genomic characteristics of patients who develop severe hyperbilirubinemia to patients who never developed a significant bilirubin level.
- Trial name
- NCT00383318
- Testing
- Gene mutation sample
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Pediatrix
Jaundice, Neonatal
Associations of Nighttime Light Exposure During Pregnancy With Neonatal Jaundice：a Multi-centre Prospective Study in China
Make a neonatal jaundiced nomogram on Chinese jaundice data by joinning the major neonate centers all around China.
- Trial name
- jaundice (NCT03805165)
- Where
- China
- Volunteers
- 2,977 people, healthy volunteers welcome
- Sponsor
- Guangdong Women and Children Hospital
Hyperbilirubinemia, Neonatal
Effect of Early Limited Formula on Total Serum Bilirubin Among Newborns With Hyperbilirubinemia
The investigators propose to conduct an exploratory pilot study, enrolling 30 exclusively breastfeeding newborns 36-96 hours of age, whose Total Serum Bilirubin (TSB) is within 0.1-3 mg/dl of the American Academy of Pediatrics…
- Trial name
- NCT01330667
- Testing
- Nutramigen Infant Formula
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Neonatal Hyperbilirubinemia
Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management
The objective of this study is to ascertain the diagnostic threshold of end-tidal carbon monoxide (ETCOc, adjusted for ambient CO levels) within the first three days postpartum, stratified by neonatal age at birth.
- Trial name
- ETCO (NCT07346976)
- Testing
- Erythrocyte Life Span Tester
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Neonatal Jaundice
Home Based Phototherapy for Neonatal Jaundice
The main purpose of the study is to deliver community health worker based prevention, early screening and management of neonatal Jaundice using battery powered LED phototherapy device at the household level.
- Trial name
- NCT03933423
- Testing
- Home based phototherapy and referral
- Where
- Bangladesh
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Unspecified Fetal and Neonatal Jaundice
Health Literacy of Parents Regarding Neonatal Jaundice
This study will be conducted as a relational descriptive study to determine the health literacy level of parents with infants between 0-28 days of age regarding neonatal jaundice.
- Trial name
- NCT05964426
- Testing
- Turkey Health Literacy Scale (TSOY-32)
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ege University
Newborn Jaundice, Hyperbilirubinemia, Neonatal
White Cover and Massage Impact on Bilirubin Levels and Phototherapy Duration in Newborns
This study aimed to examine the effect of white cover and massage application on newborns' bilirubin level and duration of phototherapy in newborns receiving phototherapy.
- Conditions
- Newborn Jaundice, Hyperbilirubinemia, Neonatal, Newborn Massage, Phototerapy
- Trial name
- NCT06209489
- Testing
- White cover
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Hyperbilirubinemia, Neonatal
Bundling Gentle Body Massage Along With Regular Position Change Under Phototherapy
This study aimed to investigate the effect of bundling gentle body massage along with regular position change on bilirubin level and clinical outcomes among full-term neonates with hyperbilirubinemia under phototherapy.
- Trial name
- NCT05260138
- Testing
- Gentle Body message, Routine NICU Care
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Umbilical Cord
Timing of Umbilical Cord Clamping: One to Three Minutes vs. After Cessation of Cord Pulsation
The timing of umbilical cord clamping has been widely discussed in the scientific community. As part of the worldwide strategies to reduce childhood iron deficiency anemia, the incorporation of late clamping (at least one minute…
- Trial name
- CORD (NCT03844490)
- Testing
- CESSATION OF CORD PULSE, CONTROL
- Where
- Brazil
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Newborn Jaundice
Influence of Breast Milk Smell on Newborns Bilirubin Level, Duration of Time Phototherapy and Comfort in Newborns Receiving Phototherapyv
ABSTRACT Purpose: This research was done for the purpose of determining the impact of breast milk smell administered to term infants hospitalized in neonatal intensive care units (NICU) due to physiological jaundice on their…
- Trial name
- NCT05167474
- Testing
- breast milk smell
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Hyperbilirubinemia, Neonatal
TCB Self-Monitoring in Healthy Term and Near-Term Neonates
The goal of this observational study is to monitor the transcutaneous bilirubin (TCB) level in healthy near-term and full-term neonates from birth to 30 days of age across China.
- Trial name
- NCT06645158
- Testing
- Transcutaneous bilirubin level monitoring
- Where
- China
- Volunteers
- 220,950 people, healthy volunteers welcome
- Sponsor
- Neonatal-Infant Brain and Behavior Development Network
Iron Deficiency, Neonatal Hyperbilirubinemia
Early Versus Delayed Cord Clamping at Term: Outcomes in Swedish Infants
Delayed clamping of the umbilical cord might prevent or slow the onset of iron deficiency by increasing the infant's iron endowment at birth.
- Trial name
- NCT01245296
- Testing
- Timing of clamping the umbilical cord
- Where
- Sweden
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Neonatal Hyperbilirubinemia
Study on Newborn Babies With a Yellow Skin Color (Neonatal Jaundice Study)
Background: Neonatal hyperbilirubinemia is the most common reason for admission in the neonatal period (first month of life) worldwide and at SMRU.
- Trial name
- NCT02361788
- Where
- Thailand
- Volunteers
- 1,710 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Neonatal Jaundice
Comparing the Effect of Vimala Massage Versus Hydrotherapy on the Clinical Outcomes of Neonatal Hyperbilirubinemia
The aim of this study is to evaluate the effect of Vimala massage versus hydrotherapy on the clinical outcomes of neonatal hyperbilirubinemia.
- Trial name
- NCT06595368
- Testing
- Vimala massage, Hydrotherapy
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Bilirubinemia, Newborn Jaundice
Effect of Repositioning Frequency Neonates Receiving Phototherapy
Purpose: The present study was conducted to determine the effect of repositioning frequency during phototherapy on bilirubin level and neonates comfort.
- Trial name
- NCT05692648
- Testing
- Supine position group, Hourly position change group, Control Group (2-hour position change)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Breastfeeding, Exclusive, Infantile Colic
The Effect of Telephone Support for Breastfeeding Follow-up on Infantile Colic and Maternal Breastfeeding Self-efficacy
This study was planned to examine the effect of telephone support for breastfeeding follow-up on physiological jaundice, exclusive breastfeeding in the first six months, infantile colic, maternal breastfeeding self-efficacy, and…
- Conditions
- Breastfeeding, Exclusive, Infantile Colic, Self Efficacy, Jaundice, Neonatal
- Trial name
- NCT04632888
- Testing
- Telephone support for breastfeeding follow-up
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University