Clinical trials: Negative Pressure Ventilation
Obstructive Sleep Apnea
Pilot Study of Negative Pressure Sleep Therapy System to Treat Obstructive Sleep Apnea
This is a pilot study to investigate the efficacy and safety of the Negative Pressure Sleep Therapy System for the treatment of obstructive sleep apnea.
- Trial name
- NCT02324790
- Testing
- iNAP® Sleep Therapy System
- Where
- 4 sites in Taiwan
- Volunteers
- 34 people
- Sponsor
- Somnics, Inc.
Primary Snore, Obstructive Sleep Apnea (Mild and Moderate).
Effects of Oropharyngeal Exercises on Patients With Primary Snore, Mild and Moderate Obstructive
Randomized study of patients with primary snore, mild and moderate obstructive sleep apnea. Protocol include 40 patients randomized to oropharyngeal exercise or use of nasal dilator, breathing exercise and nasal lavage.
- Trial name
- EOE (NCT01636856)
- Testing
- Oropharyngeal exercises, Respiratory exercises, nasal dilator, nasal lavage
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Failing Fontan Physiology, Pediatric Congenital Heart Disease
Noninvasive Negative Pressure Ventilation to Support Failing Fontan Physiology
The purpose of this study is to assess for acute hemodynamic changes after implementation of noninvasive negative pressure ventilation (as compared with spontaneous respiration) in pediatric patients with Fontan failure using…
- Trial name
- NCT03223168
- Testing
- Hayek RTX ventilator
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Michigan
Acute Hypoxemic Respiratory Failure
Physiological Effects of Continuous Negative External Pressure for Acute Hypoxemic Respiratory Failure
This study is being conducted to evaluate if wearing a non-invasive breathing support device over the chest/abdomen improves markers of breathing in patients with lung injury requiring high-flow oxygen.
- Trial name
- NCT05675345
- Testing
- HFNC only, HFNC + CNEP10, HFNC + CNEP20
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Weaning Failure
Negative Pressure Ventilation in Paediatric Patients During Weaning
Negative pressure ventilation (NPV) represent a unique form of noninvasive ventilation using negative pressure by specialized cuirass, that evolve negative pressure on the front size of chest and partially abdomen and facilitate…
- Trial name
- NEGWEAN (NCT05035290)
- Testing
- Negative pressure ventilation
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- Brno University Hospital
Chronic Obstructive Pulmonary Disease, Acute Exacerbation of COPD
Negative Pressure Ventilation-rehabilitation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease
This investigator-initiated, prospective, single center, randomized, controlled clinical trial enrolled patients with stable Global Initiative for Chronic Obstructive Lung Disease stage II-IV chronic obstruction pulmonary…
- Trial name
- NCT04843696
- Testing
- cuirass ventilator (cuirass diameter 21 cm or 34 cm, Dima Italia Srl.,Bologna, Italy), breathing training, and an educational program (relaxation techniques and a home pacing walking exercise)
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Ex-Vivo Lung Transplantation
The University of Alberta Negative Pressure Ventilation Ex-Vivo Lung Perfusion (NPV-EVLP) Trial
This project is focused on helping one of the most vulnerable patient populations in medicine, patients with end-stage chronic lung disease.
- Trial name
- UA NPV-EVLP (NCT03293043)
- Testing
- NPV-EVLP
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Sleep Apnea, Obstructive, Apnea, Sleep
Study Using Negative Pressure to Reduce Apnea
The objective of this study is to determine the safety and effectiveness of the aerSleep® II device for treatment of moderate to severe Obstructive Sleep Apnea (OSA) over 24 weeks of home use in spontaneously breathing adult…
- Trial name
- SUPRA (NCT04861038)
- Testing
- aerSleep II
- Where
- 15 sites in United States
- Volunteers
- 900 people
- Sponsor
- Sommetrics, Inc.
Acute Hypercapnic Respiratory Failure
Impact of Negative Pressure Ventilation in Patients Hospitalized With Acute Hypercapnic Respiratory Failure
The study aims to find if using a Biphasic Cuirass Ventilation is as effective as using a Non invasive Positive Pressure Ventilation in patients admitted with acute hypercapnic respiratory failure.
- Trial name
- NCT06108284
- Testing
- Intervention Arm (Biphasic cuirass ventilation)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri-Columbia
Chronic Obstructive Pulmonary Disease (COPD), Pulmonary Hyperinflation
Effect of Simeox® on Residual Volume in COPD Patients With Pulmonary Hyperinflation
Brief Summary People with severe chronic obstructive pulmonary disease (COPD) often have too much air trapped in their lungs (pulmonary hyperinflation). This makes it hard to breathe and reduces quality of life.
- Trial name
- SIMEO-RV COPD (NCT07665931)
- Testing
- Simeox
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Negative Pressure Ventilation, Right Ventricular Dysfunction
Effects of Negative Pressure Ventilation on Right Ventricular Function in Cardiological Patients
Patients receives induction of general anesthesia for interventional tricuspidal clipping and standard monitoring for this procedure including arterial and central venous line and transesophageal ultrasound.
- Conditions
- Negative Pressure Ventilation, Right Ventricular Dysfunction, Right Ventricular Failure
- Trial name
- NCT06572072
- Testing
- Negative Pressure Ventilation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Karlsburg Hospital
Sleep Apnea Syndromes, Snoring
Upper Airway Stability During Wakefulness and Sleep
Negative expiratory pressure is a technique that has been the focus of many studies in the last few years. Airway response to the application of a negative expiratory pressure (NEP) can be used to detect the presence of upper…
- Trial name
- NCT03893552
- Testing
- Negative expiratory pressure
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain
COPD Received PR
Correlation Between Pulmonary Rehabilitation and TFC
To study the effects of lung rehabilitation on the heart's hemodynamic performance of patients with chronic bidirectional lung disease when performing routine and regular PR, and found that the effects of lung rehabilitation on…
- Trial name
- NCT05240989
- Testing
- pulmonary rehabilitation
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Fu Jen Catholic University
Sleep Apnea, Obstructive
cNEP for the Treatment of Obstructive Sleep Apnea
The purpose of this study is to determine whether cNEP (continuous positive external pressure) is effective in treating obstructive sleep apnea
- Trial name
- cNEP (NCT02677168)
- Testing
- cNEP
- Where
- Canada
- Volunteers
- 71 people
- Sponsor
- Sommetrics, Inc.
Respiratory Failure
Negative Pressure Ventilation Imapcts Weaning Ventilator In Medical Intensive Care Units (ICUs)
This is a Quasi-experimental research design. The subjects are limited in intensive care unit within north medical center hospital. All subjects depend on ventilator and receive weaning plans.
- Trial name
- NCT01155596
- Testing
- negative pressure ventilator use
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital