Clinical trials: Neck
Head and Neck Cancer, Claustrophobia
Comparing Radiotherapy Immobilization Systems for Anxious HNC Patients
Background: Radiotherapy is a mainstay of treatment for ENT cancers, and its indication is frequent. Patients are positioned and immobilized using a thermoplastic mask, which is attached to the treatment table for the duration of…
- Conditions
- Head and Neck Cancer, Claustrophobia, Anxiety
- Trial name
- CRISP (NCT06257121)
- Testing
- OSMS position management
- Volunteers
- 15 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Breast Cancer, Cervical Cancer
Breast and Cervical Cancer Stigma in Rwanda
This study aims to assess breast and cervical cancer stigma and pilot a multi-modal intervention to mitigate stigma among patients, caregivers, and community health workers in Rwanda.
- Trial name
- NCT07663006
- Testing
- Behavioral: RISE Intervention, Behavioral: CHW Educational Intervention
- Where
- 2 sites in Rwanda
- Volunteers
- 1,116 people
- Sponsor
- Dana-Farber Cancer Institute
Head and Neck Neoplasms, Chemoradiotherapy
Evaluation the Effects of Herbal Gargle for Chemoradiotherapy-induced Oral Mucositis of Head & Neck Cancer, a Pilot Study.
The aim of the study is to evaluate the effects of Herbal gargle on chemoradiotherapy-induced stomatitis in head \& neck cancer patients.
- Conditions
- Head and Neck Neoplasms, Chemoradiotherapy, Stomatitis and Ulceration
- Trial name
- NCT05341206
- Testing
- Herbal gargle, Normal saline
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Intubation Complication, Cervical Discopathy
Comparison of C-Mac D Blade and Fastrach Laryngeal Mask Airway on Cervical Spine Motion Conditions
In patients with cervical spine disorders or hernia, in-line stabilization and immobilization during tracheal intubation is used to avoid neck injury. With direct laryngoscopy cranio-cervical motion can result injury.
- Trial name
- NCT03115606
- Testing
- C-Mac D Blade, Fastrach LMA
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Diskapi Teaching and Research Hospital
Esophageal Cancer
A Study of Durvalumab (MEDI4736) in Esophageal Cancer
This is a phase II, open-label, single arm, single-stage study. A total of 23 evaluable patients will be enrolled. If total number of patients free of disease relapse at 1 year is less than or equal to 15, the drug would not be…
- Trial name
- NCT02639065
- Testing
- Durvalumab
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- Shadia Jalal, MD
Head and Neck Cancer, Cancer Pain
Effect of Transcutaneous Electrical Nerve Stimulation or Acupressure on Pain in Patients With Head and Neck Cancer
This clinical trial aims to evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS), acupressure intervention, or standard care (control group) for pain management in participants hospitalized with head…
- Trial name
- NCT07051265
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Acupressure
- Where
- Taiwan
- Volunteers
- 240 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Lung Cancer, Esophageal Cancer
Cardiac Rehabilitation for Patients Receiving Radiation Therapy for Thoracic Cancers
Other than optimizing medical management of cardiac risk factors, and reducing radiotherapy (RT) dose to the heart, there currently exist no interventions to mitigate or reverse the adverse cardiac effects of RT.
- Conditions
- Lung Cancer, Esophageal Cancer, Thoracic Cancer, Hodgkin Lymphoma
- Trial name
- NCT04072393
- Testing
- Home-based cardiac rehabilitation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Washington University School of Medicine
Esophagus Cancer, Stage I, Esophagus Cancer, Stage II
Predicting Esophageal Cancer Borders Using PET-Imaging
The study examines the diagnostic precision of endosonography, mpMRI and PET/CT in defining tumor boundaries and tumor spread before and after neoadjuvant therapy and definitive surgery.
- Trial name
- PEGASUS (NCT06408116)
- Testing
- photon, surgical therapy, Chemotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital Heidelberg
Sleeve Gastrectomy, Cholecystectomy
Stanford Program to Accelerate Robotic Children's Surgery
The goal of this clinical trial is to provide additional data to confirm safety and performance of the da Vinci Xi Surgical System in a human clinical setting.
- Conditions
- Sleeve Gastrectomy, Cholecystectomy, Splenectomy, Hysterectomy
- Trial name
- SPARCS (NCT06671639)
- Testing
- da Vinci Xi Robotic Surgery System
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Stanford University
Neck Pain, Disability Physical
ML for Neck Disability Using Muscle and Joint
conduct machine learning models to identify different aspects that can give us an impression about the disability in patients with neck pain. By using 17 different classifier and regressor models.
- Trial name
- NCT05291377
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Kafrelsheikh University
Cervical Cancer, HPV
mSaada: A Mobile Health Tool
In the R21 phase of this project, investigators will: (1) work with key stakeholders and local and international developers to finalize the mSaada platform, building on the existing prototype to add patient and specimen tracking…
- Conditions
- Cervical Cancer, HPV, mHealth
- Trial name
- NCT05848557
- Testing
- mSaada
- Where
- Kenya
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Duke University
Immunotherapy;Envafolimab; Esophageal Cancer
Envafolimab Combined With Abraxane and Cisplatinas as Neoadjuvant Treatment for Resectable Esophageal Cancer
Big breakthroughs have been made in the combination therapy of immune checkpoint inhibitors when it comes to the neoadjuvant therapy of esophageal cancer.
- Trial name
- NCT05828381
- Testing
- Envafolimab, Abraxane, Cisplatin
- Volunteers
- 33 people
- Sponsor
- Fujian Medical University Union Hospital
Trauma, Tumor
Patient Outcomes Evaluation of the EBI Vuelock™ Anterior Cervical Plate System
To prospectively collect radiographic and outcome data on patients who are having cervical spine fusion surgery with the VueLock™ Anterior Cervical Plate System
- Conditions
- Trauma, Tumor, Pseudarthrosis, Scoliosis
- Trial name
- VueLock (NCT00726128)
- Testing
- VueLock™ Anterior Cervical Plate
- Where
- 4 sites in United States
- Volunteers
- 371 people
- Sponsor
- Zimmer Biomet
Esophageal Cancer
A Study of Irinotecan, Cisplatin and Celebrex in Patients With Metastatic or Unresectable Esophageal Cancer
This study is for patients with cancer of the esophagus. This study uses the drugs irinotecan, cisplatin and celecoxib. Irinotecan (also known as CPT-11) was recently approved by the U.S.
- Trial name
- NCT00183807
- Testing
- irinotecan, cisplatin, celecoxib
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Southern California
Esophagus Cancer
Rhomboid Intercostal and Subserratum Plane Block for Minimally Invasive Esophagectomy
The objective is to investigate the safety and effectiveness of rhomboid intercostal and subserratum plane (RISS) block for postoperative analgesia after minimally invasive McKeown esophagectomy (MIE-McKeown).
- Trial name
- NCT06092944
- Testing
- Catheterization, Single nerve block, Continuous nerve block
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Luo Fuchao
Cancer Cachexia, Head and Neck Cancer
The Effect of Curcumin for Treatment of Cancer Anorexia-Cachexia Syndrome in Patients With Stage III-IV of Head and Neck Cancer
A study of Curcumin to prevent cancer anorexia and cachexia Syndrom in locally advance and advance stage head and neck cancer (stage III, IV)
- Conditions
- Cancer Cachexia, Head and Neck Cancer, Head and Neck Neoplasms
- Trial name
- CurChexia (NCT04208334)
- Testing
- Curcumin
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Esophageal Cancer, Esophageal Neoplasms
TreatmENT of AnastomotiC Leakage After Esophagectomy
Rationale: Anastomotic leakage (0% - 30%) is a severe complication after esophagectomy with mortality rates approximately ranging from 2% - 12%. In addition, it is associated with a prolonged ICU treatment and hospital stay.
- Trial name
- TENTACLE (NCT03829098)
- Testing
- Intervantions for anastomotic leakage after esophagectomy
- Where
- Netherlands
- Volunteers
- 1,509 people
- Sponsor
- Radboud University Medical Center
Neck Pain
Effectiveness of Massage of the Thoracic Region in Neck Pain
Neck pain is a common disorder in industrialized countries. Manual therapy techniques have been commonly used in the treatment of this problem.
- Trial name
- NCT06256016
- Testing
- Neck pain massage, Neck and thoracic massage
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Alcala
Infertility
Effect of Cervical Discharge Removal During ET on Pregnancy Rate
Pregnancy rate may be affected by multiple factors such as embryo transfer techniques. Even small differences in embryo transfer methods may affect pregnancy rates.
- Trial name
- NCT01156181
- Testing
- Cervical discharge removal, control
- Where
- Iran
- Volunteers
- 492 people
- Sponsor
- Royan Institute
Cervical Cancer
Chemotherapy and Radiation Therapy With or Without Surgery in Treating Patients With Stage I Cancer of the Cervix
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00054067
- Testing
- cisplatin, adjuvant therapy, conventional surgery
- Where
- 50 sites in United States, Japan
- Sponsor
- Gynecologic Oncology Group