Clinical trials: Neck
Class V Dental Caries
Two Year Clinical Performance of Ion-releasing and Non Ion-releasing Composite Restorative Systems in Restoring Cervical Carious Lesions.
The goal of this clinical trial is to learn if ion releasing composite materials works to induce remineralization of caries affected dentin in adults.
- Trial name
- NCT07849426
- Testing
- Ion-releasing resin composite, Giomer based composite, Non-ion-releasing ormocer based composite
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Breast Carcinoma, Prostate Cancer Surgery
High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins
These are patients in whom a benign or malignant tumor was recorded requiring surgery. During that surgery, the surgeon will cut away the tumor as part of the treatment of the disease.
- Conditions
- Breast Carcinoma, Prostate Cancer Surgery, Thyroid Cancer, Parathyroid Adenomas
- Trial name
- NCT06835426
- Testing
- Single intravenous injection of the radiotracer, Imaging resected specimen using the high-resolution PET-CT specimen imager
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Cervical Cancer, Cervical Dysplasia
Acceptability and Efficacy of Self-sampling for Cervical Cancer Screening: A Pilot Study
In Singapore, the current cervical cancer screening uptake among women in Singapore has remained at low 50% since its introduction in 2004.
- Conditions
- Cervical Cancer, Cervical Dysplasia, Human Papillomavirus Infection
- Trial name
- NCT03813576
- Testing
- Self-collected HPV vaginal swab
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Proximal Femoral Fracture
Multimodal Approach to Improve the Outcome of Patients With a Proximal Femoral Fracture
This study is designed to compare the outcome of patients with proximal femoral fractures with different perioperative regimes: a group with a multimodal intervention and a control group.
- Trial name
- FEMO (NCT01673776)
- Testing
- PulsioFlex® Monitoring
- Where
- Germany
- Volunteers
- 132 people
- Sponsor
- Technical University of Munich
Head and Neck Cancer, Squamous Cell Carcinoma
Epigenetic Changes in Head and Neck Cancer
With this study, the investigators will investigate the epigenetic changes, which may contribute to the development of head and neck squamous cell carcinomas.
- Conditions
- Head and Neck Cancer, Squamous Cell Carcinoma, Head and Neck Squamous Cell Carcinoma, Head and Neck Neoplasms
- Trial name
- NCT04260074
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Cervical Dystonia
Theta Burst Transcranial Focused Ultrasound as a Novel Treatment for Cervical Dystonia
This study is a single-blinded, randomized control study that aims to recruit 48 participants. Participants will be "randomized" into one of the study arms of the study: active stimulation to GPi, active stimulation to DN, or…
- Trial name
- NCT07690514
- Testing
- LIFUS - GPi Active, LIFUS - DN Active
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Robert Chen
Head and Neck Cancer
Maintenance of Tarceva (Erlotinib) in Patients With Locally Advanced Head and Neck Cancer
Phase II Study of Maintenance Tarceva (Erlotinib) in patients with locally advanced Head and Neck Cancer after treatment with curative intent
- Trial name
- NCT00750555
- Testing
- Erlotinib
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Geisinger Clinic
Esophageal Squamous Cell Carcinoma
Carrelizumab Combined With Concurrent Radiotherapy and Chemotherapy for Unresectable Esophageal Squamous Cell Carcinoma
This study is a randomized, double-blind, placebo-controlled, multicenter phase III clinical study to evaluate the efficacy and safety of carrelizumab plus concurrent chemoradiotherapy compared with placebo plus concurrent…
- Trial name
- NCT06048926
- Testing
- Carrelizumab, Paclitaxel injection, Cisplatin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Whiplash Injury of Cervical Spine, Osteopathia
The Effectiveness of Osteopathic Treatment in Cervical Whiplash.
Introduction. Whiplash is common after road traffic accidents and affects millions of people worldwide; 50% develop chronic symptoms and 15% have their ability to work compromised.
- Conditions
- Whiplash Injury of Cervical Spine, Osteopathia, Quality of Life, Chronic Pain Syndrome
- Trial name
- NCT06334978
- Testing
- Osteopathic intervention
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Cetuximab Plus Dalpicilib in Patients With HPV Negative, PD-1 Resistant R/M HNSCC
This study is the first clinical study in PD-1 resistant patients with head and neck squamous cell carcinoma with drugs targeting EGFR signaling pathway combined with CDK4/6 inhibitors, which explores the new combination…
- Trial name
- NCT05721443
- Testing
- Dalpiciclib+cetuximab
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Locally Advanced Cervical Cancer, Prognostic Biomarker
Evaluation of Persistent Infection by Oncogenic Human Papillomavirus (HPV) in Patients Treated for Cervical Carcinoma and Its Relation to Prognostic Factors
Cervical cancer is strongly associated with HPV infection, yet current post-treatment follow-up relies on cytology and imaging, which have limited accuracy, particularly after radiotherapy.
- Trial name
- ANIHTA (NCT07600515)
- Volunteers
- 100 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Cervical Cancer, Cervical Intraepithelial Neoplasia Grade 2
Photodynamic Therapy Using Lutetium Texaphyrin in Treating Patients With Cervical Intraepithelial Neoplasia
Phase I trial to study the effectiveness of photodynamic therapy with lutetium texaphyrin in treating patients who have cervical intraepithelial neoplasia.
- Conditions
- Cervical Cancer, Cervical Intraepithelial Neoplasia Grade 2, Cervical Intraepithelial Neoplasia Grade 3
- Trial name
- NCT00005808
- Testing
- motexafin lutetium, photodynamic therapy, loop electrosurgical excision procedure
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- National Cancer Institute (NCI)
Cancer
Radiation, Cetuximab and Pemetrexed With or Without Bevacizumab in Locally Advanced Head and Neck Cancer
The purpose of this study is to compare the effects (good and bad) of chemoradiotherapy with or without Bevacizumab (Avastin). Chemoradiotherapy is the combination of chemotherapy (the drugs pemetrexed and cetuximab) and…
- Trial name
- NCT00703976
- Testing
- Bevacizumab, Cetuximab, Pemetrexed
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Papillomavirus Infections
Diversity Analysis of Vaginal Microbiota on Women With High-risk Human Papillomavirus Infection
Since other genital infections enhance HIV susceptibility by inducing inflammation, the investigators study the relationship between the vaginal microbiota composition and the risk of HPV infection, cervical cytological…
- Trial name
- NCT03548740
- Testing
- Human Papillomavirus
- Where
- China
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Neck Pain
Effects of Craniosacral Therapy on Chronic Neck Pain
The purpose of this randomized controlled trial is to determinate the efficacy and safety of Craniosacral Therapy in the treatment of chronic unspecific neck pain.
- Trial name
- CranioS (NCT01526447)
- Testing
- Craniosacral Therapy
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- Universität Duisburg-Essen
Primary Stage IV Hepatobiliary, Esophageal
Improving Goals of Care Discussion in Advanced Cancer Patients
The goal of this study is to increase and improve Goals of Care discussions for advanced cancer patients by training medical oncologists to conduct these discussions.
- Conditions
- Primary Stage IV Hepatobiliary, Esophageal, Colorectal Cancer, Glioblastoma
- Trial name
- NCT02374255
- Testing
- GoC intervention
- Where
- 4 sites in United States
- Volunteers
- 265 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cervical Cancer
Hydralazine and Valproate Plus Cisplatin Chemoradiation in Cervical Cancer
The current standard for locally advanced cervical cancer is concurrent cisplatin-based chemotherapy, however, the treatment results need to be improved.
- Trial name
- NCT00404326
- Testing
- Hydralazine and magnesium valproate, Punch biopsy of the primary tumor
- Where
- Mexico
- Volunteers
- 18 people
- Sponsor
- National Institute of Cancerología
Hypopharyngeal Cancer
New Strategy of Improving Treatment Outcome and Larynx-preservation Rate in Locally Advanced Hypopharyngeal Carcinoma
To develope stratification treatment for the patients who have locally advanced hypopharyngeal carcinoma. Experimental group patients were treated individually according to the response status after induction chemotherapy…
- Trial name
- NCT03558035
- Testing
- Induction CT+ CRT group, Concurrent CRT group
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Chinese Academy of Medical Sciences
Cervical Spondylosis
Effect of Cupping Therapy on Nitric Oxide Level in Patients With Cervical Spondylosis
this study will be conducted to investigate the effect of cupping therapy on the nitric oxide level in patients with cervical spondylosis
- Trial name
- CT (NCT06271525)
- Testing
- cupping therapy
- Volunteers
- 60 people
- Sponsor
- Shady Abdelsattar Refaat
Malignant Tumor of Head and/or Neck, Radiotherapy; Complications
Acupuncture for Prevention and Treatment of Oral-related Complications Caused by Radiotherapy for Head and Neck Cancer
A study on the efficacy and safety of acupuncture for the prevention and treatment of oral-related complications caused by radiotherapy for head and neck malignant tumors
- Trial name
- NCT06272617
- Testing
- verum acupuncture
- Where
- China
- Volunteers
- 138 people
- Sponsor
- West China Hospital