Clinical trials: Nausea
Postoperative Nausea and Vomiting, Laparoscopic Cholecystectomy
The Role of High Intraoperative Fraction of Inspired Oxygen in Preventing Postoperative Nausea and Vomiting
Postoperative nausea and vomiting is one of the most common complications after laparoscopic surgeries. The investigators aimed to evaluate the effects of intraoperative high fraction of inspired oxygen in preventing…
- Trial name
- NCT06390280
- Testing
- intraoperative Fraction of Inspired Oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Ankara City Hospital Bilkent
Laparoscopic Surgery, Breathing Exercise
The Effect of Respiratory Exercise After Laparoscopic Surgery
Laparoscopic surgery (LS) enables the patient to experience the desired result with smaller incisions in the postoperative period, more aesthetically, stress-free and less painful.
- Trial name
- NCT05624346
- Testing
- Deep-Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bartın Unıversity
Gynecologic Disease
Opioid-free Anesthesia in Gynecologic Surgery
Post-operative nausea and vomiting (PONV) is common for the patients undergoing laparoscopic gynecologic surgery. PONV is a major factor for patient dissatisfaction, delayed patient recovery and increased medical expenses.
- Trial name
- NCT04700761
- Testing
- Opioid-free anesthesia, Opioid-using anesthesia
- Where
- South Korea
- Volunteers
- 164 people
- Sponsor
- Seoul National University Bundang Hospital
Chemotherapy-Induced Nausea and Vomiting (CINV), Radiotherapy-induced Nausea and Vomiting (RINV)
A Study to Compare the Bioavailability of Ondansetron Following Nasal (NS003) and IV Administration in Healthy Adults
A Study to Compare the Bioavailability of Ondansetron Following Nasal (NS003) and IV Administration in Healthy Adults
- Conditions
- Chemotherapy-Induced Nausea and Vomiting (CINV), Radiotherapy-induced Nausea and Vomiting (RINV), Postoperative Nausea and Vomiting
- Trial name
- NCT07868861
- Testing
- NS003 Ondansetron HCl microspheres powder for nasal application, Ondansetron Solution for IV infusion 8mg
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nasus Pharma
Functional Dyspepsia, Gastroparesis
Brain-Gut Yoga for Functional Dyspepsia and Gastroparesis (FD-GP)
The purpose of this research study is to assess whether using a yoga-based intervention in practice is feasible (possible) and acceptable to patients with Functional Dyspepsia and/or Gastroparesis (FD-GP).
- Trial name
- FD-GP (NCT06732453)
- Testing
- Seated Yoga Skills Training in Functional Dyspepsia and Gastroparesis (FD-GP)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Rhinoplasty
The Effect of Ice Cold Mentholated Water Spray After Rhinoplasty
This clinical trial aims to evaluate the effects of a menthol-infused cold water spray on thirst perception, dry mouth, nausea, and physiological parameters in patients after rhinoplasty.
- Trial name
- NCT07233057
- Testing
- Menthol Cool Water Spray, Ice water spray
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Firat University
Nausea With Vomiting Chemotherapy-Induced
Buccal Film Versus IV Injection Palonosetron for Moderately Emetogenic Chemotherapy Induced Nausea and Vomiting
Phase 2 study to compare efficacy, safety and PK of palonosetron, a long acting 5-HT3 receptor antagonist, by buccal film delivery compared to iv injection for chemotherapy induced nausea or vomiting (CINV).
- Trial name
- NCT04592198
- Testing
- Palonosetron Hydrochloride Buccal Film 0.25 Mg, Palonosetron Hydrochloride Buccal Film 0.5 Mg, Palonosetron Hydrochloride, 0.25 Mg/5 mL Intravenous Solution
- Where
- 7 sites in United States
- Volunteers
- 22 people
- Sponsor
- Xiamen LP Pharmaceutical Co., Ltd
Nausea and Vomiting, Unspecified Adult Solid Tumor, Protocol Specific
APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer
This randomized phase III trial is studying APF530 and dexamethasone to see how well they work compared with palonosetron and dexamethasone in preventing nausea and vomiting in patients receiving chemotherapy for cancer.
- Trial name
- NCT00343460
- Testing
- APF530, dexamethasone, Palonosetron Hydrochloride
- Where
- 52 sites in United States
- Volunteers
- 1,428 people
- Sponsor
- Heron Therapeutics
Thyroid Surgery for Benign Disease
Steroid Before Thyroidectomy
We evaluated the effects of giving a single dose of steroid before thyroid surgery in a single institutional, double-blinded, randomized controlled trial.
- Trial name
- NCT00619086
- Testing
- Dexamethason Helvepharm ®
- Where
- Switzerland
- Volunteers
- 72 people
- Sponsor
- University of Bern
Cancer
Stimulation of Auricular Acupuncture-Point for Chemotherapy-Induced Nausea/Vomiting
The purpose of this study is to evaluate auricular acupuncture as an antiemetic treatment compared with sham acupuncture and with no acupuncture in patients receiving moderately-high to highly emetogenic chemotherapy.
- Trial name
- NCT00360841
- Testing
- Auricular acupuncture
- Where
- Taiwan
- Volunteers
- 103 people
- Sponsor
- National Taiwan University Hospital
Postoperative Ileus, Postoperative Nausea
Assessing Gastric Motility and Distention in Postoperative Gastrointestinal Surgery Using Bedside Gastric Ultrasound: Predicting Risk of Aspiration Pneumonia, Ileus, Return of Bowel Function
Point-of-care gastric ultrasound will be used to measure stomach contents postoperative in patients who underwent colorectal surgery.
- Conditions
- Postoperative Ileus, Postoperative Nausea, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT04747691
- Testing
- Bedside gastric ultrasound
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eric Schwenk
Hypotension, Shivering
Effects of Different Kinds, Different Doses of 5-HT3 Receptor Antagonists on Prevention of Hypotension
The purpose of this study is to estimate effects of different kinds, different dose of 5-HT3 receptor antagonists on prevention of hypotension after spinal anesthesia
- Conditions
- Hypotension, Shivering, Nausea and Vomiting, Vasopressor
- Trial name
- NCT01669213
- Testing
- ramosetron, ondansetron
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Postoperative Nausea and Vomiting
Effect of Right-stellate Ganglion Block in Preventing Postoperative Nausea and Vomiting in Gynecological Laparoscopic Patients
Postoperative nausea and vomiting is one of the common postoperative complications. Studies have reported that without any antiemetic prevention treatment, the overall incidence of PONV in surgical operations is up to 20-30%, and…
- Trial name
- NCT06426186
- Testing
- Right-stellate ganglion block
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Nausea, Vomiting
Efficacy of Dexamethasone Added to Ramosetron for Preventing Postoperative Nausea and Vomiting in Highly Susceptible Patients Following Spine Surgery
The purpose of this study is to study the efficacy of dexamethasone added to ramosetron for preventing postoperative nausea and vomiting in highly susceptible patients following spine surgery.
- Trial name
- NCT01013012
- Testing
- ramosetron with saline, ramosetron with dexamethasone
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cancer of the Cervix
Oral Ondansetron Versus Transdermal Granisetron (Sancuso) for Women With Cervical, Endometrial or Vaginal Cancer Receiving Pelvic Chemoradiation
The goal of this clinical research study is to compare granisetron (when given through a patch) to ondansetron (when taken by mouth) for reducing nausea and vomiting in women with cervical, endometrial, or vaginal cancer having…
- Trial name
- NCT01536392
- Testing
- Granisetron, Ondansetron, Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 76 people
- Sponsor
- M.D. Anderson Cancer Center
Vomiting, Nausea
Inhaled Isopropyl Alcohol for Treatment of Nausea
To determine the efficacy of inhaled isopropyl alcohol in treating nausea/vomiting among pediatric patients compared with the conventional ondansetron, or placebo treatment in a tertiary care pediatric emergency department.
- Conditions
- Vomiting, Nausea, Children, Only
- Trial name
- NCT05418244
- Testing
- Inhaled Isopropyl Alcohol, Oral Ondansetron
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Cancer-related Problem/Condition
Effectiveness of Medical Taping Concept in Cancer Patients
Nausea and vomiting are two of the side effects associated with the most common antineoplastic chemotherapy treatments. The Medical Taping Concept (MTC) is an economical technique, easy to apply.
- Trial name
- NCT02823314
- Testing
- Cure Tape™ covering T 7 and T 8 dermatomes, Cure Tape™ away from dermatomes T 7 and T 8
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Postoperative Nausea and Vomiting
Preemptive Versus Preventive Antiemetic Treatment
Patients aged between 20 and 70 years, ASA physical status I-III, and scheduled for laparoscopic cholecystectomy under general anaesthesia will be enrolled in the study.
- Trial name
- NCT03023306
- Testing
- Antiemetics perioperatively
- Where
- Greece
- Volunteers
- 115 people
- Sponsor
- University of Athens
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University