Clinical trials: Nausea
Perineal Surgery
Intrathecal Atropine Versus Intravenous Ondasetron in Post Operative Nausea Due to Intrathecal Morphine
To compare between intrathecal atropine versus preoperative administration of IV ondansetron in decreasing incidence of post operative nausea and vomiting related to intrathecal opioids in post operative period in perineal…
- Trial name
- NCT05137288
- Testing
- Ondansetron , atropine and bupivacaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Residual Neuromuscular Block, Neuromuscular Blockade Monitoring
Comparison of Sugammadex and Sugammadex-neostigmine Combination in the Antagonism of Moderate Neuromuscular Block
In this prospective randomized controlled study the investigators compare the sugammadex-neostigmine combination and single dose sugammadex in terms of side effects and cost for the antagonism of moderate neuromuscular block…
- Trial name
- NCT05228223
- Testing
- Neuromuscular monitoring, reverse of NMB with sugammadex, reverse of NMB with Sugammadex and neostigmin low dose
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Breast Cancer
Individualised Versus Standard Care for Breast Cancer Patients at High-risk for Chemotherapy-induced Nausea and Vomiting The ILIAD Study
The purpose of this study is to evaluate whether adding olanzapine 5mg to standard antiemetic medication can significantly reduce chemotherapy-induced nausea and vomiting in breast cancer patients receiving emetogenic…
- Trial name
- NCT02861859
- Testing
- Olanzapine
- Where
- Canada
- Volunteers
- 221 people
- Sponsor
- Ottawa Hospital Research Institute
Vomiting, Nausea
A Study of Ramosetron Plus DX, Dexamethasone, Compared to Granisetron Plus DX for the Prevention of Vomiting and Nausea
The purpose of this study is to compare the efficacy and safety of ramosetron plus dexamethasone injection with granisetron plus dexamethasone injection for the prevention of chemotherapy-induced vomiting and nausea.
- Trial name
- NCT00272285
- Testing
- Ramosetron, Granisetron
- Where
- 2 sites in Taiwan
- Volunteers
- 287 people
- Sponsor
- Astellas Pharma Inc
Postoperative Nausea and Vomiting
Caffeine in the Prevention of Post-operative Nausea and Vomiting
The objective of this study is to determine if caffeine 500 mg intravenously is efficacious when added to standard anti-emetic prophylaxis in the prevention of post-operative nausea and vomiting (PONV) in patients undergoing…
- Trial name
- NCT00130026
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hyperemesis Gravidarum
Pregnancy Specific Nausea Questionnaire (PUQE) Translated and Tested in Norwegian
Nausea in early pregnancy (emesis gravidarum) is very common but most often self-limiting. Hyperemesis gravidarum; where nausea and vomiting is severe and protracted is potentially dangerous for the woman and her foetus and…
- Trial name
- PUQE-N (NCT01836835)
- Testing
- Pregnancy Unique Questionnaire of Emesis (PUQE), 24 hours self-reported nutritional intake form
- Where
- 2 sites in Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Postoperative Nausea and Vomiting
Clinical Use of Baxter Animated Retching Faces (BARF) Scale in Children
Pediatric research in the management of nausea has been limited by the absence of a reliable method to quantify the intensity of this subjective symptom.
- Trial name
- BARF (NCT02421952)
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Nausea and Vomiting, Postoperative
An Economic Study of HSK21542 Injection for Prevention of Postoperative Nausea and Vomiting
This study analyzed the efficacy and safety results of HSK21542 injection for the prevention of postoperative nausea and vomiting in a multicentre, randomized, double-blind, placebo-controlled dose-exploration study, as well as…
- Trial name
- NCT06359535
- Testing
- HSK21542
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Mengchang Yang
Postoperative Nausea and Vomiting (PONV), Heart Rate Variability (HRV)
Predictive Role of HRV for PONV in Laparoscopic Cholecystectomy
Postoperative nausea and vomiting (PONV) are among the most common complications following general anesthesia (GA), significantly affecting patient comfort and recovery.
- Conditions
- Postoperative Nausea and Vomiting (PONV), Heart Rate Variability (HRV), Laparoscopic Cholecystectomy
- Trial name
- NCT06948708
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Postoperative Nausea and Vomiting
The Effect of Prophylactic Antiemetic Dexamethasone on Plasma Cortisol Levels
Dexamethasone is a synthetic corticosteroid that has been proven to be effective and relatively safe for the prophylaxis of the postoperative nausea and vomiting (PONV).
- Trial name
- NCT01524731
- Testing
- Saline, Dexamethasone
- Where
- 2 sites in Canada
- Volunteers
- 63 people
- Sponsor
- William Li Pi Shan
Nausea
Reducing Up-set Stomach and Vomiting After Surgery Using Essential Oils
The purpose of this study is to determine if aromatherapy (essential oil) is effective at reducing up-set stomach and vomiting after surgery and in reducing the need for up-set stomach medications
- Trial name
- NCT03370328
- Testing
- Peppermint oil, Ginger oil
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Rochester
Postoperative Nausea and Vomiting, Post Operative Pain
Effect of Dexmedetomidine on Prevention of Postoperative Nausea and Vomiting in Children
this study will aim to evaluate the effects of dexmedetomidine, dexamethasone and Ondansetron on the prevention of postoperative nausea and vomiting in children undergoing dental rehabilitation surgery.
- Conditions
- Postoperative Nausea and Vomiting, Post Operative Pain, Emergence Delirium
- Trial name
- NCT05124067
- Testing
- Dexamethasone, Ondansetron, Dexmedetomidine
- Where
- Saudi Arabia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Tanta University
Laparoscopic Cholecystectomy
Osmaniye State Hospital"
Objective: It was conducted as a randomized controlled experimental study to determine the effect of progressive relaxation exercise applied after laparoscopic cholecystectomy on postoperative pain, nausea and vomiting.
- Trial name
- OSH (NCT06511271)
- Testing
- relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Osmaniye Korkut Ata University
Bariatric Surgery, Postoperative Nausea and Vomiting
Botulinum Toxin Pyloroplasty to Reduce Postoperative Nausea and Vomiting After Sleeve Gastrectomy
A common problem following sleeve gastrectomy surgery is called postoperative nausea and vomiting (PONV). This problem is uncomfortable for patients, and can also lead to other complications, including pneumonia.
- Trial name
- NCT03701919
- Testing
- Botulinum toxin pyloroplasty, Normal saline pyloric injection
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Albany Medical College
Breast Cancer
Efficacy and Safety of Non Invasive Vagal Stimulation to Prevent Chemotherapy-induced Nausea
Despite pharmaceutical innovations, chemotherapy induced nausea is frequent and largely participating to alter our patients quality of life.
- Trial name
- SILENCE (NCT04937309)
- Testing
- non invasive auricular vagal stimulation, usual medical treatment
- Where
- 8 sites in France
- Volunteers
- 338 people
- Sponsor
- University Hospital, Tours
Postoperative Nausea
How Pregnant Women and Their Babies Metabolize Ondansetron Compared to a Group of Non-pregnant Women
This is called "Aim 1" of the investigators' NIH grant. Ondansetron (Zofran) is a safe and effective drug used in pregnant women to prevent nausea but the investigators do not know what effect pregnancy may have on the metabolism…
- Trial name
- Zofran_PK (NCT01801475)
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Idiopathic Gastroparesis
Effects of Global Osteopathic Manual Treatments in Patients With Idiopathic Gastroparesis
Global osteopathic manual treatments will decrease the severity score of the Gastroparesis Cardinal Symptom Index tool of patients with idiopathic gastroparesis.
- Trial name
- NCT02232334
- Testing
- Global Osteopathic Manual Treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kathleen Brannan Brown, Inc.
Nausea and Vomiting Caused by Chemotherapy
Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Docetaxel Plus Cyclophosphamide
The goal of this clinical trial is to learn if auricular point stimulation plus dexamethasone works to effectively prevent or suppress nausea and vomiting caused by docetaxel combined with cyclophosphamide in breast cancer…
- Trial name
- ADDC (NCT07537699)
- Testing
- Auricular point stimulation plus dexamethasone
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Postoperative Nausea and Vomiting
Adjuvant Effect of Dexmedetomidine in Ultrasound (USG) Guided Transvers Abdominis Plane Block
A total of 60 adult patients American Society of Anesthesiologists physical status I,II, III were randomized to Group B (n = 30) receiving TAP block with 0.25% bupivacaine and Group D (n = 30) with 0.5 mcg/kg dexmedetomidine…
- Trial name
- USG (NCT02331563)
- Testing
- Dexmedetomidine, 0.25 % bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kırıkkale University
Breast Cancer, Colorectal Cancer
The Effects of Acupuncture and the Therapist´s Communication on Chemotherapy Induced Nausea and Vomiting
Background: Chemotherapy-induced nausea and vomiting (CINV) is a common and burdensome side-effect of emetogenic chemotherapy. CINV affects both the patient's quality of life and induces high costs within the health-care system.
- Conditions
- Breast Cancer, Colorectal Cancer, Bladder Cancer, Chemotherapy-induced Nausea and Vomiting
- Trial name
- NCT03232541
- Testing
- Standard care, Genuine acupuncture
- Where
- Sweden
- Volunteers
- 198 people
- Sponsor
- Västernorrland County Council, Sweden