Clinical trials: Nasolabial Folds
Nasolabial Folds
Safety & Tolerability Study That Compares Restylane to Restylane With Lidocaine While Correcting Wrinkles in the Nasolabial Folds
Safety \& tolerability study that compares Restylane to Restylane with Lidocaine (Restylane-L) while correcting wrinkles in the area around your nose.
- Trial name
- NCT00797459
- Testing
- Restylane and Restylane-L
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medicis Global Service Corporation
Nasolabial Folds
Safety Study That Compares Perlane to Perlane With Lidocaine (Perlane-L) While Correcting Wrinkles in the Area Around Your Nose
Safety study that compares Perlane to Perlane with Lidocaine while correcting wrinkles in the area around your nose.
- Trial name
- NCT00823069
- Testing
- Perlane and Perlane-L
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medicis Global Service Corporation
Nasolabial Folds
Pilot Evaluation of Platelet Rich Fibrin Matrix (PRFM) for the Correction of Nasolabial Folds
Platelets are a component of blood, which contain factors which can enhance wound healing. This study proposes to evaluate the clinical response of laugh lines treated with a concentrated preparation of the subject's own…
- Trial name
- NCT00874094
- Testing
- Platelet rich fibrin matrix
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The New York Eye & Ear Infirmary
Bilateral Nasolabial Fold Wrinkles
Safety and Efficacy Study of Isolagen Therapy in the Treatment of Nasolabial Fold Wrinkles
The purpose of this study is to evaluate the safety profile and the treatment effect of Isolagen TherapyTM compared with placebo when administered to bilateral nasolabial fold wrinkles.
- Trial name
- NCT00655356
- Testing
- Autologous Human Fibroblasts (azficel-T)
- Where
- 6 sites in United States
- Volunteers
- 218 people
- Sponsor
- Castle Creek Biosciences, LLC.
Moderate to Severe Nasolabial Folds
Post-Market Study of JUVÉDERM VOLIFT™ With Lidocaine for the Correction of Nasolabial Folds
A prospective, open-label, multi-center, observational, post-market study evaluating JUVÉDERM VOLIFT™ for the correction of moderate to severe nasolabial folds
- Trial name
- NCT01680497
- Testing
- Crosslinked hyaluronic acid dermal filler
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Allergan
Nasolabial Folds
Safety and Effectiveness of Sculptra Aesthetic for Correction of Nasolabial Folds.
This study has been designed to evaluate the safety of Sculptra Aesthetic as a single regimen for correction of Nasolabial Fold (NLF) contour deficiencies after changes in reconstitution and injection procedures compared to the…
- Trial name
- NCT03780244
- Testing
- Sculptra Aesthetic 8ml, Sculptra Aesthetic 5ml
- Where
- 5 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Wrinkles
A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Volume Plus Versus YVOIRE Volume in Nasolabial Fold Injection
The objective of this study was to evaluate the efficacy and safety of HA IDF II plus (with lidocaine) injected in the nasolabial fold compared to HA IDF II (without lidocaine).
- Trial name
- NCT02340078
- Testing
- HA IDF II plus, HA IDF II
- Volunteers
- 62 people
- Sponsor
- LG Life Sciences
Wrinkles
Safety Study of Cosmetic Tissue Augmentation in People of Color
Elevess is intended for all skin types. However, further study of all soft tissue fillers is needed in people of color because of the increasing use of cosmetic dermal filler products.
- Trial name
- NCT01147172
- Testing
- Elevess
- Where
- 9 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Anika Therapeutics, Inc.
Correction of Moderate to Severe Nasolabial Folds
Evaluation of Pain With Belotero® Balance With Integral Lidocaine for Correction of the Nasolabial Folds
Demonstrate the effectiveness of Belotero Balance with lidocaine (Test group) for the reduction of injection-related pain in comparison to Belotero Balance without lidocaine (Control group) for the correction of NLFs.
- Trial name
- NCT03319719
- Testing
- Belotero® Balance with integral lidocaine, Belotero® Balance
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Merz North America, Inc.
Nasolabial Folds
Evaluation of Pain With Radiesse® With Lidocaine for Nasolabial Folds
To assess pain during nasolabial fold treatment using Radiesse® Injectable Dermal Filler with lidocaine
- Trial name
- NCT01069354
- Testing
- Radiesse® Injectable Dermal Filler with Lidocaine, Radiesse® Injectable Dermal Filler without Lidocaine
- Where
- 2 sites in Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Moderate to Severe Nasolabial Folds
Saypha® Volume LIdocaine in Nasolabial Folds
Comparison of saypha Volume Lidocaine from 2 different manufacturing locations in correcting moderate to sever nasolabial folds
- Trial name
- SAVINO (NCT04883632)
- Testing
- Saypha Volume Lidocaine
- Where
- 3 sites in Austria
- Volunteers
- 110 people
- Sponsor
- Croma-Pharma GmbH
Facial Wrinkles
Safety and Effectiveness of Belotero® in Subjects With Fitzpatrick Phototypes IV Through VI
This is a study to assess how safe and effective an investigational product, Belotero® is in people with all skin types with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00922623
- Testing
- Belotero®
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- Merz North America, Inc.
Wrinkles
A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Classic Plus Versus YVOIRE Classic in Nasolabial Fold Injection
The objective of this study was to evaluate the efficacy and safety of HA IDF plus (with lidocaine) injected in the nasolabial fold compared to HA IDF (without lidocaine).
- Trial name
- NCT02340091
- Testing
- HA IDF plus, HA IDF
- Volunteers
- 62 people
- Sponsor
- LG Life Sciences
Temporary Correction of Wrinkles
Clinical Study to Evaluate the Correction of Wrinkles and Folds and Safety of YVOIRE Classic Versus Restylane in Nasolabial Fold Intradermal Injection
This study was purposed to evaluate the non-inferiority of HA IDF, a hyaluronic acid product, in terms of correction of wrinkles and safety in nasolabial fold intradermal injection, compared to Restylane, the control preparation.
- Trial name
- NCT03738020
- Testing
- HA IDF (YVOIRE classic), Restylane
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Nasolabial Fold, Hypoplastic
Princess® VOLUME Lidocaine for the Correction of Nasolabial Folds
In this study, eligible subjects with moderate to severe nasolabial folds will be treated with Princess® VOLUME Lidocaine and will return for follow-up assessments 2, 4, 24 and 36 weeks after the treatment.
- Trial name
- VINO (NCT03050710)
- Testing
- Princess® VOLUME Lidocaine
- Where
- 3 sites in Austria
- Volunteers
- 62 people
- Sponsor
- Croma-Pharma GmbH
Nasolabial Folds, Wrinkles
TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines, and Juvéderm® Ultra XC for the Correction of Nasolabial Folds
The purpose of this study is 1) to compare the effectiveness and safety of TEOSYAL® RHA Global Action versus Juvéderm® Ultra XC, and 2) to compare the effectiveness and safety of TEOSYAL® RHA Deep Lines versus Juvéderm® Ultra XC…
- Trial name
- NCT02195427
- Testing
- TEOSYAL® RHA Global Action, TEOSYAL® RHA Deep Lines
- Where
- 5 sites in United States
- Volunteers
- 148 people
- Sponsor
- Teoxane SA
Wrinkle, Nasolabial Fold
RHA® 4 NLF Cannula
This is a randomized, controlled, single-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA®4 injected in NLFs with a cannula is non-inferior to RHA®4 injected in NLFs with a sharp…
- Conditions
- Wrinkle, Nasolabial Fold, Aging
- Trial name
- NCT04754646
- Testing
- Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Correction of Nasolabial Folds
Post Market Study Evaluating Princess Filler Lidocaine for the Correction of Nasolabial Folds
In this study, eligible subjects with moderate to severe nasolabial folds will be treated with Princess® FILLER Lidocaine and will return for follow-up assessments 2, 4, 24 and 36 weeks after the treatment.
- Trial name
- FINO (NCT03611491)
- Testing
- Princess FILLER Lidocaine
- Where
- 2 sites in Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Nasolabial Folds, Marionette Lines
Emervel for the Correction of Lower Face Wrinkles & Folds
This study is designed to 1. evaluate the naturalness of facial expressions in motion (2D video images), by treating investigator assessment 2.
- Conditions
- Nasolabial Folds, Marionette Lines, Wrinkles
- Trial name
- NCT02718040
- Testing
- Emervel Classic and/or Deep Treatment Group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Correction of Nasolabial Folds
Observational Study to Evaluate Long-term Safety and Biodegradability of YVOIRE Volume s
To evaluate long-term safety of YVOIRE volume s by incidence of adverse events including injection site local reactions and biodegradability.
- Trial name
- NCT02661737
- Testing
- YVOIRE volume s
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences