Clinical trials: Nasal Congestion
Common Cold/Flu, Nasal Congestion
Fixed-dose Combination of 1000 mg Dipyrone Monohydrate + 60 mg Caffeine + 4 mg Chlorpheniramine Maleate in Improving Symptoms of the Common Cold and Flu in Adults
Phase III clinical trial to evaluate the efficacy and safety of a fixed-dose combination of 1000 mg dipyrone monohydrate + 60 mg caffeine + 4 mg chlorpheniramine maleate in improving symptoms of the common cold and flu in adults.
- Conditions
- Common Cold/Flu, Nasal Congestion, Nasal Obstruction
- Trial name
- PANAMA (NCT07626437)
- Testing
- dipyrone monohydrate 1000 mg + chlorpheniramine maleate 4 mg + caffeine 60 mg, dipyrone monohydrate 500 mg + chlorpheniramine maleate 2 mg + caffeine 30 mg
- Where
- 15 sites in Brazil
- Volunteers
- 620 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Rhinitis Medicamentosa
A Study Comparing Proponent Solution - Nasal Spray (PSNS) With Salt Water for Treating Nasal Congestion Symptoms in Adults With Rebound Nasal Congestion While Weaning From Nasal Decongestant Sprays
The purpose of the study was to test if the PROPONENT® nasal spray works, if it is safe, and if it helps participants to stop using addictive nasal decongestant sprays.
- Trial name
- PROUD (NCT06817967)
- Testing
- PSNS, ISNS
- Where
- 7 sites in Norway
- Volunteers
- 194 people
- Sponsor
- Pharma Nordic AS
Nasal Congestion
Bioequivalence Between Two Oral Formulations of Diphenhydramine Hydrochloride
The purpose of this study is to determine if two formulations of diphenhydramine hydrochloride are bioequivalent.
- Trial name
- NCT00662337
- Testing
- Diphenhydramine hydrochloride
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Nasal Congestion
Study on Hypertonic Saline Nasal Spray
Phytosun decongestant nasal spray is a class I medical device registered in the European Union for the treatment of nasal congestion. The spray contains hypertonic seawater and essential oils.
- Trial name
- PhytosunDecon (NCT02100605)
- Testing
- Phytosun, decongestant, nasal spray
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Omega Pharma
Nasal Congestion
A User Study of the Soniflow System for Nasal Congestion Relief
The Soniflow System consists of an acoustic vibrational headband paired with a Smartphone App to provide rapid relief of nasal congestion.
- Trial name
- NCT04910139
- Testing
- Soniflow System
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Third Wave Therapeutics
Nasal Congestion, Nursing
Effects of Different Nasal Irrigation Methods on Pain Level, Crying and Procedure Times in Nasal Congestion in Infants
This study aimed to evaluate the effects of different nasal irrigation (NI) methods for relieving nasal obstruction on pain, crying and procedure times, and physiologic parameters in infants with acute upper respiratory tract…
- Trial name
- NCT06691620
- Testing
- Nasal irrigation with isotonic saline, Nasal irrigation with hypertonic saline, Nontraumatic nasopharyngeal aspiration
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Allergic Rhinitis, Chronic Rhinitis
Laser Posterior Nasal Nerve Neurolysis
This clinical trial aims to learn if laser posterior nasal nerve neurolysis can treat chronic rhinitis in adults. It will also learn about the safety of laser posterior nasal nerve neurolysis.
- Conditions
- Allergic Rhinitis, Chronic Rhinitis, Rhinorrhea, Sneezing
- Trial name
- LPN3 (NCT07050992)
- Testing
- Laser posterior nasal nerve neurolysis
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chiayi Christian Hospital
Seasonal Allergic Rhinitis
POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis)
Comparative study on clinical efficacy and safety of levocetirizine and desloratadine as measured by the subject's satisfaction/dissatisfaction after one week of treatment
- Trial name
- NCT00160537
- Testing
- Levocetirizine
- Volunteers
- 200 people
- Sponsor
- UCB Pharma
Common Cold, Headache
Efficacy and Safety of Sinutab on Subjects in the Setting of a Common Cold
The purpose of this study is to investigate the efficacy and safety for a marketed sinus allergy product, Sinutab, in the treatment of nasal congestion and headache.
- Conditions
- Common Cold, Headache, Nasal Congestion
- Trial name
- NCT00378144
- Testing
- Pseudoephedrine/Paracetamol
- Where
- Belgium
- Volunteers
- 469 people
- Sponsor
- McNeil AB
Allergic Rhinitis
Study of Nasonex in the Relief of Nasal Congestion in Patients With Seasonal Allergic Rhinitis (Study P05583)
This study seeks to prospectively demonstrate that Nasonex is better than placebo in relieving nasal congestion in patients with seasonal allergic rhinitis.
- Trial name
- NCT00728416
- Testing
- Mometasone furoate nasal spray (MFNS)
- Volunteers
- 333 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Intranasal Steroids and Oxymetazoline in Allergic Rhinitis
We hypothesize that once daily use of oxymetazoline will not cause significant rhinitis medicamentosa and that the combination of fluticasone furoate plus oxymetazoline leads to faster relief of nasal congestion secondary to…
- Trial name
- NCT00584987
- Testing
- Fluticasone furoate, Oxymetazoline
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Seasonal Allergic Rhinitis
Effect of Loratadine/Montelukast Combination on Congestion in SAR Patients Exposed to Pollen in an EEU (Study P04822)
This is study of LMC, phenylephrine, and placebo in subjects with SAR. There are three visits: At Visit 1, subjects will be evaluated for participation and, if they qualify, will attend Visit 2 for priming.
- Trial name
- NCT00423995
- Testing
- Loratadine/montelukast combination
- Volunteers
- 379 people
- Sponsor
- Organon and Co
Seasonal Allergic Rhinitis
A Randomized, Double-blind, Placebo-controlled Study on the Effect of CVT-E002 in Patients With Seasonal Allergic Rhinitis
You are being asked to take part in a research study of COLD-fX, a product designed to boost the immune system. COLD-fX is an extract from the roots of North American ginseng and it may offer some benefit to people with seasonal…
- Trial name
- NCT00726401
- Testing
- COLD-fX
- Where
- 4 sites in Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Afexa Life Sciences Inc
Rhinitis, Allergic, Seasonal
The Effects of Phenylephrine Compared With Those of Placebo and Pseudoephedrine on Nasal Congestion in Subjects With Seasonal Allergic Rhinitis (SAR)(P04579)
This is a Phase 3, single-dose, investigator-blind, randomized, placebo-controlled, crossover study, conducted at a single site in Austria, outside of the normal grass pollen season.
- Trial name
- NCT00276016
- Testing
- phenylephrine, pseudoephedrine
- Volunteers
- 39 people
- Sponsor
- Organon and Co
Allergic Rhinoconjunctivitis, Chronic Urticaria
Pharmacokinetic Study of Bilastine in Children From 2 to < 12 Years of Age With Either Allergic Rhinoconjunctivitis (AR) or Chronic Urticaria (CU)
The conduct of this clinical trial is aimed at determining the most suitable dose regimen for children in different age groups, and secondarily to assess the safety and tolerability of bilastine in this paediatric population…
- Trial name
- NCT01081574
- Testing
- Bilastine
- Where
- 7 sites in Australia, Germany and 1 more
- Volunteers
- 36 people
- Sponsor
- Faes Farma, S.A.
Itching, Runny Nose
Efficacy and Safety of Auricular Acupressure in Treating Allergic Rhinitis
Allergic rhinitis (AR) is a global health problem affecting approximately 10% to 40% of the population worldwide, with an increasing trend. It significantly impacts health and quality of life.
- Conditions
- Itching, Runny Nose, Sneezing, Nasal Congestion
- Trial name
- NCT06323304
- Testing
- Auricular acupressure, Standard treatment
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Nasal Congestion Due to Allergic Rhinitis
Study to Find Out Whether Participants With a History of Stuffy Nose Due to Allergic Reactions in the Nose Would Intend to Buy Drug Phenylephrine Hydrochloride Extended Release Tablets After Receiving it Once in This Study
The researchers in this study want to find out whether participants with a history of stuffy nose due to allergic reactions in the nose would intend to buy drug Phenylephrine Hydrochloride (Phenylephrine HCl) extended release…
- Trial name
- NCT04534452
- Testing
- Phenylephrine HCl (Sinus Comfort, BAY112476)
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Bayer
Nasal Congestion
Bioequivalence of Single Dose Phenylephrine Extended Release Tablets and Phenylephrine HCl Immediate Release Tablets Dosed Every Four Hours (P08340)(COMPLETED)
This study will assess the food-effect bioavailability of an extended release formulation of phenylephrine HCl and its bioequivalence to the marketed immediate release phenylephrine HCl product.
- Trial name
- NCT01354418
- Testing
- Phenylephrine HCl Extended Release, Phenylephrine HCl Immediate Release
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Nasal Congestion
Sonu Real-World Use Clinical Study to Treat Moderate to Severe Nasal Congestion
Real world utilization of Acoustic Resonance Therapy for symptoms of Nasal Congestion
- Trial name
- NCT06024564
- Testing
- Sonu Acoustic Resonance Therapy
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Third Wave Therapeutics