Clinical trials: NICU
Prematurity Complications, NICU Infants
A Pilot Study Comparing Telehealth and In-Person Therapy Service Delivery Following NICU Discharge
20 high-risk parent-infant dyads hospitalized in a 58-bed level IV NICU will be randomized to either receive Telehealth or in-person Baby Bridge services.
- Conditions
- Prematurity Complications, NICU Infants, Early Intervention, Telehealth
- Trial name
- BabyBridge (NCT06893003)
- Testing
- Baby Bridge
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Breastfeeding, Prematurity
Facilitation and Barriers to Breastfeeding in the NICU
To date, there is a paucity of research focusing on maternal breastfeeding goals, how these goals may change after an unexpected event such as a preterm birth, and how mothers of ill and preterm infants define breastfeeding…
- Trial name
- NCT00527956
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Newborn Diseases, Breast Milk Collection
Sensory Mindfulness for NICU Mothers: Effects on Breast Milk, Well-Being, and Stress
Abstract Background: Breast milk is the optimal source of nutrition for infant growth and development and provides important physical and psychological benefits for mothers.
- Conditions
- Newborn Diseases, Breast Milk Collection, Well-being, MİNDFULNESS
- Trial name
- NCT07346339
- Testing
- Sensory Mindfulness Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Neonatal Disease
Neonatal Admission in Assuit University Children Hospital
There are many causes of admission of neonates in Neonatal Intensive Care Unit.So knowing such causes and their outcomes will give us knowledge about different risk factors of each disease and the prognosis of each cause.
- Trial name
- NCT04279301
- Volunteers
- 120 people
- Sponsor
- Assiut University
Necrotizing Enterocolitis
Pilot Study of the Feasibility of Feeding Preterm Infants With Fresh Versus Frozen Mother's Own Breast Milk in the NICU
Necrotizing enterocolitis (NEC) is a severe inflammatory disorder of the intestine that primarily affects very low birth weight (<1,500 g)/very preterm infants (≤32 weeks' gestation); it is also the leading cause of death in the…
- Trial name
- NCT03258957
- Testing
- Fresh Milk
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Huiqing Sun
Preterm Birth, Parent-Child Relations
Epigenetics and Protective Factors in the Preterm Infant
Preterm infants (PT) spend their first weeks of life in the Neonatal Intensive Care Unit (NICU) where they are exposed to unfavorable conditions with different effects on child development including long-term alterations in…
- Conditions
- Preterm Birth, Parent-Child Relations, Epigenetics
- Trial name
- EPIC (NCT04804280)
- Testing
- DNA methylation of target genes, Functional Magnetic Resonance Imaging (fMRI) acquisition
- Where
- Italy
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Respiratory Distress Syndrome (Neonatal), Intubation Complication
InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS
The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated…
- Conditions
- Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
- Trial name
- Aero-05 (NCT05960929)
- Testing
- Infasurf Aero™
- Where
- 10 sites in United States
- Volunteers
- 220 people
- Sponsor
- ONY
Infant, Premature, Diseases, Mothers
Home Support for Mothers Whose Premature Infants
Premature births are a challenging process for parents in many ways. Especially after the treatment and care in the hospital, they are concerned about whether they will be able to provide adequate care for their baby at home.
- Trial name
- NCT04741672
- Testing
- Providing guidance after discharge routine procedure and calling one week after discharge., Discharge routine procedure.
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Magnetic Resonance Imaging
Clinical Use of a New Neonatal MRI System
The purpose of the present study is to make medically indicated state of the art/high end magnetic resonance imaging (MRI) exams available to all infants in the Cincinnati Children's Hospital Medical Center (CCHMC) Neonatal…
- Trial name
- NCT01801865
- Testing
- GE OPTIMA MR430s with HDX/GE Electronics
- Where
- United States
- Volunteers
- 657 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Infant, Premature, Diseases
Probiotics On Resistant Bacteria Colonization In Preterm Receiving Antibiotics
In this study, the investigators investigated the effect of probiotic use on colonization of resistant microorganisms in newborn preterm infants receiving antibiotics.
- Trial name
- NCT02178267
- Testing
- Lactobacillus reuteri (biogai AB, Sweden)
- Volunteers
- 51 people
- Sponsor
- Baskent University
Infant Development, Patient Comfort
Effect Of Early Intervention Program Applied To Premature Infants
Purpose: This study was conducted to evaluate the effect of singing a lullaby with compassionate touch on early comfort and later on development of developmental support program in premature infants in the neonatal intensive care…
- Conditions
- Infant Development, Patient Comfort, Nursing Caries, Premature Infant Disease
- Trial name
- NCT06191757
- Testing
- supported with the developmental support program
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Pain, Postoperative, Pain
Intravenous Acetaminophen For Postoperative Pain in the Neonatal Intensive Care Unit
The goal of this pilot randomized clinical trial is to determine the effect of the addition of IV acetaminophen to opioid-based pain regimes for infants admitted to the neonatal intensive care unit (NICU) after surgery.
- Trial name
- IVA POP NICU (NCT05678244)
- Testing
- Acetaminophen
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McMaster Children's Hospital
Premature Birth
Developmental Care Program in Neonatal Intensive Care Unit
This project is a Randomised Clinical Trial that includes a family centred education intervention and/or non-directive active listening counselling intervention with families of preterm infants at risk for sensori-motor disorders.
- Trial name
- CIN (NCT05573945)
- Testing
- Family Education and Active Listening, Family Education
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Pisa
Human Milk/Breastfeeding
Human Milk Feeding Rates Post-NICU Discharge
The purpose of this study is to discover the incentives and barriers to human milk use and breast-feeding in the NICU graduate. By better understanding the incentives and barriers we believe we can define better methods for…
- Trial name
- NCT02692521
- Testing
- Human Milk
- Where
- 5 sites in United States
- Volunteers
- 1,160 people
- Sponsor
- Pediatrix
Bacterial Transmission Surveillance, Neonatal Intensive Care Unit
Bacterial Transmission Dynamics Study
Infections with multiply antibiotic-resistant bacteria represent a major cause of preventable morbidity and mortality amongst hospitalized neonates worldwide.
- Conditions
- Bacterial Transmission Surveillance, Neonatal Intensive Care Unit, Drug Resistance
- Trial name
- BTS (NCT02401204)
- Testing
- Longitudinal surveillance study
- Where
- Thailand
- Volunteers
- 97 people
- Sponsor
- University of Oxford
Central Line Bloodstream Infections
The Effectiveness of Silver Alginate (Algidex) Patch in the Prevention of Central Line Infections in Very Low Birth Weight Infants
The purpose of this study is to determine whether silver alginate (Algidex) patch is effective in the prevention of central line infections in very low birth weight infants.
- Trial name
- NCT00964093
- Testing
- Silver Alginate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Premature Birth
Family Integrated Care (FICare) in Level II NICUs
In Alberta, nearly one in every twelve babies is born too soon (preterm). Preterm babies are at greater risk for breathing and feeding problems, as well as infections, than babies born on their due date (full term).
- Trial name
- FICare (NCT02879799)
- Testing
- Implement Family Integrated Care
- Where
- 10 sites in Canada
- Volunteers
- 765 people
- Sponsor
- University of Calgary
Retinopathy of Prematurity
Improve Screening Criteria for Retinopathy of Prematurity in Two French Center
The aim of the study is to assess whether a delay of the first examination can be safely considered in French population. Secondary objectives are to describe retinopathy of prematurity (ROP) in a population of premature from two…
- Trial name
- DEREP3 (NCT05152862)
- Testing
- Laser, Anti VEGF
- Where
- France
- Volunteers
- 886 people
- Sponsor
- Centre Hospitalier Sud Francilien
Anemia
NeoSpHb Study: Can a Painless Device Detect Anaemia in Babies Without Blood Tests? A Study in the Neonatal Intensive Care Unit (NICU)
The goal of this study is to evaluate the diagnostic performance and feasibility of non-invasive spectrophotometric haemoglobin (SpHb) measurement for detecting anaemia in infants admitted to the Neonatal Intensive Care Unit…
- Trial name
- NeoSpHb (NCT07788703)
- Testing
- Spectrophotometry hemoglobin
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- University of Malaya
Preterm Birth
Surfactant Replacement Guided by Early Lung Ultrasound Score in Preterm Newborns With Respiratory Distress Syndrome
Lung immaturity is a major issue in neonatal unit.The surfactant administration improves the pulmonary prognosis in premature infants with hyaline membrane disease who escape continuous positive airway pressure (CPAP).
- Trial name
- ECHOSURF (NCT04775459)
- Testing
- Surfactant administration until 2020, Surfactant administration since 2021
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne