Clinical trials: N-Acetylcysteine
Carpal Tunnel Surgery, Trigger Finger Disorder
NAC-REPAIR for Post-surgical Pain
This pilot asks whether peri-operative N-acetylcysteine (NAC) improves recovery after common outpatient hand/foot-ankle surgery-specifically, does NAC reduce pain and opioid use and enhance function by modulating…
- Conditions
- Carpal Tunnel Surgery, Trigger Finger Disorder, De Quervain Syndrome, Guyon's Canal
- Trial name
- NCT07227649
- Testing
- NAC
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Arizona
Kidney Failure
NASPI: N-Acetylcysteine vs. Ascorbic Acid for Prevention of Contrast Induced Nephropathy in Renal Insufficiency Undergoing Coronary Catheterization
The contrast induced nephropathy (CIN) has been known to be associated with significant clinical and economic consequences. Many studies were performed to find the pathophysiology and preventive measures for CIN.
- Trial name
- NCT00356954
- Testing
- N-acetylcystein, ascorbic acid
- Where
- South Korea
- Volunteers
- 250 people
- Sponsor
- Seoul National University Hospital
PCOS
N-Acetylcysteine and L-carnitine in Pcos
N-Acetylcysteine and L-carnitine were used in pcos patients
- Trial name
- NCT03164421
- Testing
- N-Acetylcysteine, L-carnitine
- Where
- Egypt
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Biliary Atresia
Tolerability of Enteral NAC in Infants
Biliary atresia (BA) is a neonatal liver disease characterized by impaired bile flow and is the most common indication for pediatric liver transplantation.
- Trial name
- NCT06260566
- Testing
- N-Acetylcysteine
- Volunteers
- 12 people
- Sponsor
- Sanjiv Harpavat
Thrombotic Microangiopathy
N-Acetylcysteine as Therapy for Transplantation- Associated Thrombotic Microangiopathy
This multicenter, prospective, single-arm clinical trial aims to evaluate the efficacy and safety of N-acetylcysteine (NAC) for treating Transplantation-Associated Thrombotic Microangiopathy (TA-TMA), a severe complication of…
- Trial name
- NCT07279610
- Testing
- N-Acetylcysteine (NAC) Treatment
- Where
- China
- Volunteers
- 44 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Chronic Kidney Failure
Improved Estimation of GFR by Cystatin C in Preventing Contrast Induced Nephropathy by NAC or Zn
Background Prevention of contrast media (CM) induced nephropathy (CIN) by pharmacological prophylaxis (e.g. N-acetylcysteine; NAC) is controversially discussed.
- Trial name
- NCT00399256
- Testing
- Acetylcysteine, Zinc
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Gulf War Syndrome
GWICTIC: NAC Mechanistic Study in Gulf War Veterans
This mechanistic study will test if NAC affects chronic oxidative stress and depletion of antioxidants in GWI participants. Blood specimen collection and neuroimaging will be used to determine whether NAC affects serum…
- Trial name
- NAC (NCT04987775)
- Testing
- N-Acetyl Cysteine
- Where
- 7 sites in United States
- Volunteers
- 170 people
- Sponsor
- Nova Southeastern University
Diabetes Mellitus, Critical Limb Ischemia
N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes
In this pilot clinical study the investigators propose to conduct a prospective, randomized, double-blinded, placebo-controlled clinical trial for 30 days for participants with critical limb ischemia (CLI) who undergo a major…
- Conditions
- Diabetes Mellitus, Critical Limb Ischemia, Lower Limb Amputation Knee, Peripheral Arterial Disease
- Trial name
- NCT03253328
- Testing
- Active Arm N-acetyl cysteine (NAC)
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Washington University School of Medicine
Lymphoma
A Study of N-Acetylcysteine (N-AC) in People Receiving CAR T-cell Therapy for Lymphoma
The purpose of this study is to test the safety of N-AC when given in combination with Yescarta to people with lymphoma. This study will test different doses of N-AC to find the highest dose that causes few or mild side effects…
- Trial name
- NCT05081479
- Testing
- N-Acetylcysteine
- Where
- 7 sites in United States
- Volunteers
- 9 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
NAFLD
Efficacy of N-Acetylcysteine in Improving/Normalizing ALT & AST in Patients of NAFLD
Currently researches are focusing on the effect of antioxidants in the treatment of non-alcoholic fatty liver disease (NAFLD). Since N-acetyl cysteine (NAC) has been proven to have antioxidant and anti-inflammatory properties…
- Trial name
- NCT05576428
- Testing
- Diet and exercise, NAC with diet and exercise
- Volunteers
- 100 people
- Sponsor
- Dow University of Health Sciences
Acute Myeloid Leukemia
NAC for Promoting Hematopoietic Recovery in Patients With Acute Myeloid Leukemia After Chemotherapy
This is a prospective single-arm clinical study to evaluate the role of NAC after chemotherapy among patients with AML can promote hematopoietic recovery and does not affect the remission rate of the leukemia.
- Trial name
- NCT06024031
- Testing
- N-acetyl-L-cysteine
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University People's Hospital