Clinical trials: Myopia Progressing
Myopia, Progressive, Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression
This is a monocenter, randomized, controlled, parallel-group, double-masked clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation at baseline compared to a…
- Trial name
- NCT05331378
- Testing
- Test myopia control lenses, Single vision lenses
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Progressive
Efficacy and Safety of Low-concentration Atropine for Myopia Control in Chinese Children and Adolescents
To investigate the efficacy and safety of three low-concentration atropine sulfate eye drops (0.01%, 0.025% and 0.05%) in controlling the progression of myopia in Chinese children and adolescents through a two-year clinical trial.
- Trial name
- LAMC (NCT05597163)
- Testing
- low concentration atropine (0.01%), low concentration atropine (0.025%), low concentration atropine (0.05%)
- Volunteers
- 588 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Progressive
Stellest Lens Wear in Adult Progressing Myopes
It is expected that myopia progression stabilises in the late teenage years, however, some studies report that myopia progression continues through early adulthood in as many as one third of myopes.
- Trial name
- SWAP (NCT06520124)
- Testing
- Essilor® Stellest® spectacle lens, Single-vision spectacle lens
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Myopia, Progressive
Low-dose Atropine for Myopia Control in Children
Myopia (nearsightedness) is the most common eye disorder. Only second to age, it is the main risk factor for major degenerative eye diseases such as glaucoma, macular degeneration or retinal detachment.
- Trial name
- AIM (NCT03865160)
- Testing
- Atropine eye drops, 0.01%, Atropine eye drops, 0.02%
- Where
- 19 sites in Germany
- Volunteers
- 302 people
- Sponsor
- University Eye Hospital, Freiburg
Myopia, Progressive, Children, Only
Myopia Control With Orthokeratology Contact Lenses in Spain
The purpose of this prospective study is to assess the efficacy, safety and patient-reported outcomes of the Menicon Z Night orthokeratolgy contact lens for reducing myopia progression in children.
- Conditions
- Myopia, Progressive, Children, Only, Contact Lens Complication, Perception, Self
- Trial name
- MCOS (NCT04806763)
- Testing
- Menicon Z Night, Control
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Progressive, Children, Only
Long-term Efficacy of Orthokeratology Contact Lens Wear in Controlling the Progression of Childhood Myopia
To assess the long-term efficacy of the Menicon Z Night orthokeratology contact lens in controlling the progression of childhood myopia
- Trial name
- MCOS7 (NCT04806698)
- Testing
- Menicon Z Night, Control
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Myopia, Progressive
Double Helix Design Defocus Lens Spectacle (RACE) for Myopia Control
This study uses 1.585 double helix defocus lens PC lenses with a unique optical design that includes a globally coherent visible area and complementary left and right helices that can form clear images.
- Trial name
- NCT05894382
- Testing
- Double Helix Design Defocus Lens Spectacle (RACE), single-vision spetacle lens
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Multicenter Evaluation of Near Vision and Outdoor Time in Kids Study
Currently, optical and pharmacological interventions have been developed to prevent the progression of childhood myopia. However, no myopia control strategy has been shown to have complete efficacy in controlling myopia…
- Trial name
- MENOK (NCT06119243)
- Testing
- Vivior
- Where
- 5 sites in United States, Australia
- Volunteers
- 230 people
- Sponsor
- The University of New South Wales
Myopia, Progressive
Near Horizontal Heterophoria in Chinese Children
This study aimed to assess the association of refraction and axial length with near-horizontal heterophoria in a large population-based study of school-aged Chinese children.
- Trial name
- NCT05007626
- Testing
- axial length and refractive error
- Where
- China
- Volunteers
- 15,081 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Progressive, Refractive Errors
Repeated Low-Level Red-Light Therapy and Orthokeratology in Fast-progressing Myopia Control
The purpose of this multicenter randomized clinical trial is to evaluate the adjunctive effect of repeated low-level red-light therapy (RLRL) and orthokeratology (ortho-k) on myopia control in ortho-k non-responders who have…
- Conditions
- Myopia, Progressive, Refractive Errors, Eye Diseases
- Trial name
- NCT04722874
- Testing
- Ortho-k lenses, RLRL
- Where
- 3 sites in China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
Myopia
Myopia Control Efficacy of Second-generation DIMS Spectacle Lenses on Fast Progressing Myopes - Auxiliary Group
The purpose of this study is to examine the efficacy and performance of the Defocus Incorporated Multiple Segments (DIMS) and a variant of DIMS (D2) spectacle lenses on controlling myopia progression in fast progressing myopic…
- Trial name
- NCT05888805
- Testing
- DIMS spectacle lens
- Where
- Hong Kong
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Myopia, Progressive
Myopia-control Efficacy by Peripheral Defocus Lens (PDL)
The proposed study below aims to assess the effect of customized Bestivue PDL lenses on retinal image quality and myopia control. A total of 160 subjected would be enrolled in and randomized to allcoate into four groups.
- Trial name
- NCT05373693
- Testing
- Single vision lens, +2D PDL, +3D PDL
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia, Myopia, Progressive
Multicenter RCT: LED Red Light Dose-Response in Myopia Progression Control
The goal of this clinical trial is to verify the effectiveness and safety of non-laser LED red light combined with defocus lens therapy for controlling myopia progression and evaluate the impact of different intervention…
- Trial name
- NCT07330180
- Testing
- Yingtong Vision Rehabilitation Instrument, Hoya DIMS multi-point myopia defocus lens
- Where
- 7 sites in China
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Myopia, Progressive
Safety and Efficacy of Blue Star MAX-5 Lenses in Myopia Control
The goal of this randomised controlled clinical trial is to compare the effects of a new type of concentric columnar microstructure lens and single-vision spectacle lenses on myopia progression in Chinese children aged 8-11 years…
- Trial name
- NCT06647160
- Testing
- Blue star MAX-5 spectacle lens, Single-vision spectacle lens
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Effectiveness of 0.01% Atropine Sulfate Solution in Controlling of Myopia Progression in Children
Increasing number of myopic children and significant complications of high myopia enhance the necessity of effective control strategy.
- Trial name
- NCT04338373
- Testing
- 0.01% Atropine sulfate solution in "Comfort Drops" ("AVIZOR S.A.", Spain)
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- The V.P. Vyhodcev Eye Hospital
Myopia Progressing, Childhood
Topical 0.01% Atropine for the Control of Fast Progressing Myopia
Myopia prevalence has dramatically increased worldwide in recent years in the general population and among children. Progressive myopia increases gradually with growth until the age of 20-25 years.
- Trial name
- Myopie-STOP (NCT04173780)
- Testing
- Atropine 0.01%
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Myopia, Progressive
Choroidal Response to Novel Spectacle Lens to Control Myopia Progression
Diurnal variations in the thickness of the choroid have been reported in the literature, and, more recently, the role of the choroid has been studied with respect to its role in myopia (near-sightedness) progression.
- Trial name
- CHERRY (NCT03818880)
- Testing
- Novel spectacle lens design
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia Progressing
Myopia Control With a Innovative Spectacle Lens - A Cessation Study
The purpose of this study is to quantify myopic progression following cessation of a innovative spectacle lenses after 3 years' use.
- Trial name
- NCT06884527
- Testing
- Single Vision Lens to A innovative spectacle lens
- Where
- 5 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Progressive
Evaluation of the Safety and Efficacy of the D.D.C Dual-control Technology Spectacle Lenses in Delaying the Progression of Myopia: a Randomized Controlled Trial
The burden of myopia among Chinese children and adolescents is severe and trending toward younger ages, making control of myopia progression a public health priority.
- Trial name
- NCT07264361
- Testing
- D.D.C dual-control technology spcetacle lenses, Aspheric single-vision lenses
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University