Clinical trials: Myopia
Myopia
Wearing Behavior and Eye Length Changes in Children With Myopia Wearing Myopia Control Spectacle Lenses
The goal of this clinical trial is to learn how children with myopia aged 8 to 15 years move their eyes and heads during near-vision tasks while wearing different spectacle lenses, and if wearing myopia control spectacle lenses…
- Trial name
- NCT07780851
- Testing
- Single Vision Lens (SVL), Myopia Control Lens (MCL)
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
Essilor® Stellest® Lenses Multicentre European Study (SLOMES)
The goal of this post-market clinical follow up Study is to demonstrate the efficacy, safety, acceptability, and quality of life implications of Essilor® Stellest® spectacle lenses in slowing myopia progression in European…
- Trial name
- SLOMES (NCT06263946)
- Testing
- Essilor® Stellest® spectacle lenses
- Where
- 3 sites in France, Ireland and 1 more
- Volunteers
- 150 people
- Sponsor
- Essilor International
Refractive Errors, Myopia
Evaluation of Delefilcon A Contact Lenses
The purpose of the study is to evaluate the lens fit characteristics of delefilcon A contact lenses with different base curves and diameters.
- Trial name
- NCT06884202
- Testing
- Delefilcon A contact lenses with different base curves and diameters, Delefilcon A contact lenses with standard base curves and diameters
- Where
- 16 sites in United States
- Volunteers
- 267 people
- Sponsor
- Alcon Research
Refractive Error - Myopia Simple
Evaluation of the Safety and Efficacy of PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3)
The goal of this clinical trial is to learn if PEGAVISION Silicone Hydrogel Daily Disposable Soft Contact Lenses (G3) are safe and effective for vision correction in adults.
- Trial name
- NCT06995781
- Testing
- Experimental Intervention, Active Comparator Intervention
- Volunteers
- 69 people
- Sponsor
- Pegavision Corporation
Choroidal Neovascularization Secondary to Pathologic Myopia
A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic Myopia
This is a Phase III, multicenter, randomized, double-masked, active comparator-controlled study evaluating the efficacy and safety of faricimab in patients with myopic choroidal neovascularization (CNV).
- Trial name
- POYANG (NCT06176352)
- Testing
- Faricimab, Ranibizumab
- Where
- 63 sites in Australia, China and 9 more
- Volunteers
- 280 people
- Sponsor
- Hoffmann-La Roche
Nearsightedness, Near Sightedness
The Safety and Efficacy of SYD-101 in Children With Myopia
Myopia, or nearsightedness, is the most common eye disorder, often affecting more than 40% of adults in Europe, Asia and the USA.
- Conditions
- Nearsightedness, Near Sightedness, Near-sightedness
- Trial name
- STAR (NCT03918915)
- Testing
- SYD-101 0.01%, SYD-101 0.03%, Vehicle
- Where
- 47 sites in United States, Austria and 1 more
- Volunteers
- 852 people
- Sponsor
- Sydnexis, Inc.
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression (DAL)
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05840185
- Testing
- Test myopia control lenses (DAL)
- Where
- Singapore
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Essilor International
Pre-myopia
Evaluation of Contact Lenses and Myopia.
This study will evaluate the effect of dual focus contact lenses on Myopia prevention.
- Trial name
- NCT07566234
- Testing
- Test Lens - Dual Focus
- Where
- China
- Volunteers
- 110 people
- Sponsor
- CooperVision International Limited (CVIL)
Juvenile Myopia, Myopia
Assessment of DOT Spectacles in Chinese Children
This is a randomized, controlled, evaluator-blinded, multicenter, two-arm parallel group clinical trial to evaluate the continued safety and efficacy of Diffusion Optics Technology (DOT) spectacle lenses by comparing to single…
- Trial name
- CATHAY (NCT05562622)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 5 sites in China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
MiSight 1 Day Safety Post-Approval Study
The purpose of this post-approval study is to confirm the safety of daily disposable soft contact lens wear among the intended patient population for the MiSight 1 Day lens in the US.
- Trial name
- NCT05285527
- Testing
- MiSight 1 Day
- Where
- 50 sites in United States, Canada
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
MiSight 1 Day Post-Approval Study for Effectiveness and Visual Symptoms
The purpose of this post-approval study is to confirm the effectiveness of the MiSight 1 Day lens in clinical practices within the US and to assess the stability of the myopia reduction over one-year post-treatment.
- Trial name
- NCT05285553
- Testing
- MiSight 1 Day, Proclear 1 day
- Where
- 30 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Hyperopia, Myopia
A Clinical Comparison of Two Soft Contact Lenses (C24-755)
The aim of this study is to compare the short-term clinical performance of two soft contact lenses.
- Trial name
- NCT06758076
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- United Kingdom
- Volunteers
- 52 people
- Sponsor
- CooperVision, Inc.
Myopia
A Controlled Evaluation of Optical Defocus Parameters on Transient Changes in Axial Length Using Kubota Glass
This study will assess the optimal performance characteristics of optical defocus on transient changes in axial length with Kubota Glass, using a randomized, double-masked, 5-treatment, 5-period crossover design with…
- Trial name
- NCT07686289
- Testing
- KG1, KG2, KG3
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia
Comparing Myopia Control Spectacle Lenses for Visual Comfort, Adaptation, and Satisfaction in Myopic Children
The goal of this clinical trial is to demonstrate that the visual comfort, adaptation, and overall satisfaction associated with the use of the test spectacle lenses are not inferior to those of the control spectacle lenses in…
- Trial name
- EVASION (NCT07683481)
- Testing
- HADAL Spectacle Lenses, Stellest® Spectacle Lenses
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
Visual Performance of Highly Aspherical Lenslet Spectacles in Children (Ancillary to WS10246)
To evaluate the visual performance of (high and low contrast distance visual acuity, reading speed, near visual acuity, and near contrast sensitivity) of HAL spectacle lenses (habitual correction) in comparison with single vision…
- Trial name
- FIN-3102 (NCT07668102)
- Testing
- HAL spectacle lens, Single Vision spectacle lens
- Where
- 7 sites in United States
- Volunteers
- 88 people
- Sponsor
- Essilor International
Myopia
Comparison of Efficacy Between Two Myopia Control Lenses
This is a one-year, mono-centre, randomize, double-masked, monocular cross-over clinical trial designed to test and compare the efficacy of the new lens design in slowing down the increase of axial length and controlling myopia…
- Trial name
- NCT06148870
- Testing
- Myopia Control Lens-1 (MCL1), Myopia Control Lens-2 (MCL2)
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Study Comparing Eye Growth Over Time in Children Using Two Myopia Control Lenses
The goal of this clinical trial is to investigate the short-term changes in the eye structure while wearing two types of lenslet-based myopia control lenses over a period of 6 months in children aged 6 to 13 years with myopia.
- Trial name
- NCT07253064
- Testing
- MCL 1, MCL 2
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
Observational Survey Study on the Impact of Myopia and Its Complications on Quality of Life.
This study aims to assess the impact of myopia in childhood and its long-term complications in adulthood on health-related Quality of Life (HRQoL), providing valuable data for cost-effectiveness models.
- Trial name
- NCT06912802
- Testing
- Non-Intervention
- Where
- 10 sites in Denmark, France and 5 more
- Volunteers
- 344 people
- Sponsor
- Santen SAS
Juvenile Myopia
Control of Myopia Using Novel Spectacle Lens Designs
Randomized, controlled, multisite, subject-and observer-masked, 3-arm parallel group clinical trial of 36-month duration to evaluate the safety and efficacy of a novel spectacle lens design in reducing the progression of juvenile…
- Trial name
- CYPRESS (NCT03623074)
- Testing
- Novel spectacle lens design, Spectacle lenses
- Where
- 14 sites in United States, Canada
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia, Progressive
Choroidal Response to Novel Spectacle Lens to Control Myopia Progression
Diurnal variations in the thickness of the choroid have been reported in the literature, and, more recently, the role of the choroid has been studied with respect to its role in myopia (near-sightedness) progression.
- Trial name
- CHERRY (NCT03818880)
- Testing
- Novel spectacle lens design
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.