Clinical trials: Myopia; Refractive Error
Myopia
Visual Outcomes and Contrast Sensitivity After Myopic LASIK
Evaluate visual outcomes and contrast sensitivity for subjects undergoing bilateral myopic LASIK procedure using the 200 kHz WaveLight® FS200 Femtosecond Laser and the WaveLight® Allegretto Wave® Eye-Q Laser.
- Trial name
- NCT01746589
- Testing
- bilateral myopic LASIK
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Daniel S. Durrie, MD
Myopia
A Study to Evaluate the Product Performance of the PureVision®2 High Definition (HD) Contact Lens
The objective of this study is to evaluate the product performance of PureVision2 HD contact lenses.
- Trial name
- NCT01416142
- Testing
- PureVision2 HD contact lenses, Spectacles
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression.
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05534022
- Testing
- Test myopia control lenses (BSL)
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Pathological Myopia
Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia
This study is designed to evaluate the efficacy and safety of two different dosing regimens of 0.5 mg ranibizumab given as intravitreal injection in comparison to verteporfin PDT in patients with visual impairment due to…
- Trial name
- NCT01217944
- Testing
- Ranibizumab, Verteporfin PDT
- Where
- 74 sites in Austria, Canada and 18 more
- Volunteers
- 277 people
- Sponsor
- Novartis Pharmaceuticals
Myopia
Effects of Blue of Glasses VS Standard Lenses on Contrast Sensitivity & Visual Fatigue in Myopic & Non-Myopic Adults
This study investigates the effects of blue light-blocking glasses compared to standard lenses on contrast sensitivity and visual fatigue in myopic and non-myopic adults.
- Trial name
- NCT06739525
- Testing
- Blue Light-Blocking Glasses (Intervention Group), Standard Lenses (Control Group)
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Superior University
Astigmatism, Myopia
Evaluation of Mesopic Visual Acuity and Patient Satisfaction Following Ray-Tracing-Guided LASIK
To provide comprehensive evaluation of WaveLight® Plus technology by assessing impact on both functional low-light vision and patient reported outcomes
- Trial name
- NCT07790185
- Testing
- Wavelight Plus
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Vance Thompson Vision
Myopia, Astigmatism
Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction
This study evaluates differences in postoperative visual outcomes between patients receiving Topography-Guided LASIK in one eye and Small Incision Lenticule Extraction in the other eye.
- Trial name
- NCT05611294
- Testing
- Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Refractive Error, Myopia
A Comparative Study of Two Daily Disposable Contact Lenses in Higher Myopia Subjects
The purpose of this study is to compare the change from baseline in central corneal curvature at one week, between 2 silicone hydrogel lenses, in higher myopic subjects.
- Trial name
- NCT02066922
- Testing
- Delefilcon A contact lens, Narafilcon A contact lens, Spectacles
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Adolescent, Adult
Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation
To observe the retinal microvascular alteration during 3 months follow-up after Implantable Collamer Lens (ICL) operation in moderate and high myopia patients using quantitative optical coherence tomography angiography (OCTA)…
- Conditions
- Adolescent, Adult, Human, Male
- Trial name
- NCT04443231
- Testing
- Optical Coherence Tomography Angiography
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Myopia
Validation of the Vision Trainer Clinical Decision-Support Software
This study is a prospective, randomized, crossover clinical investigation designed to evaluate the accuracy, efficiency, and usability of the Vision Trainer software for subjective refraction.
- Trial name
- NCT07773753
- Testing
- Software Trainer
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Pennsylvania
Myopia, Orthokeratology
The Relationship of Relative Corneal Refractive Power Shift and Axial Length in Adolescents With Orthokeratology Lens
Orthokeratology lens is an effective method for myopia control. This study analyzed the relationship between the relative corneal refractive power shift and change of axial length in adolescents with orthokeratology lens.
- Trial name
- NCT05348369
- Where
- China
- Volunteers
- 364 people
- Sponsor
- Tianjin Eye Hospital
Myopia, High Myopia
Efficacy and Safety of Spectacle Lenses With H.A.L.T. MAX Technology on High Myopia Control in Children and Adolescents
Children aged 7-14 years with high myopia were randomly assigned to a control group or an intervention group at a 1:1 ratio. The intervention group wore H.A.L.T.
- Trial name
- NCT07120737
- Testing
- H.A.L.T. MAX spectacles
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Presbyopia
A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optimize the Ocular Surface Before Implantation
The objective of this study is to evaluate the Raindrop® Near Vision Inlay for the improvement of near vision in presbyopic patients with treatments to optimize the ocular surface before corneal inlay surgery.
- Trial name
- NCT03126877
- Testing
- Mitomycin C, Raindrop Near Vision Inlay
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Whitten Laser Eye
Myopia, Progressive Myopia
Atropine Alone vs Atropine Plus Bifocal Spectacles for Myopia Control in Children
Background: Myopia (nearsightedness) is a growing global health concern, projected to affect 50% of the world population by 2050.
- Conditions
- Myopia, Progressive Myopia, Refractive Errors
- Trial name
- COMBAT-Myopia (NCT07614113)
- Testing
- Atropine Sulfate 0.05% Ophthalmic Solution, Bifocal Spectacles
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- University of Faisalabad
Myopia
Exploratory Study on the Effect of SAT-001 on Choroidal Thickness in Pediatric Myopia Patients
This clinical trial aims to exploratively compare and evaluate the structural changes in the eye (specifically changes in choroidal thickness) pre- and post-treatment of the investigational medical devices ('SAT-001' and…
- Trial name
- NCT06729723
- Testing
- SAT-001, modified SAT-001
- Where
- 2 sites in South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- S-Alpha Therapeutics, Inc.
Myopia
Comparative Performance of PureVision Lens Designs
The objective of this study is to evaluate the performance of the PureVision Lens designs when worn on a 30-day continuous wear basis
- Trial name
- NCT00661687
- Testing
- Currently Marketed PureVision Contact Lens., Alternate Design of the PureVision Contact Lens.
- Where
- 2 sites in Malaysia, Philippines
- Volunteers
- 206 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Refractive Ametropia
The Impact of 'A Miss Is as Good as a Mile': Is Compensation Necessary for Minimal Ocular Deviation in Myopic Laser Surgery?
The goal of this clinical trial is to evaluate the effect of intraoperative kappa-angle compensation on postoperative visual quality in patients undergoing small incision lenticule extraction (SMILE) using the VisuMax 800…
- Trial name
- NCT07512115
- Testing
- Apply compensation to the Kappa angle., Apply no compensation to the Kappa angle
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University