Clinical trials: Myocardial Blood Flow Reserve, open to volunteers
Chronic Coronary Syndrome
CMR-derived Quantitative Perfusion for Prediction of FFR
Patients will undergo quantitative perfusion assessment in cardiovascular magnetic resonance imaging (dual bolus or dual sequence approach) as well as invasive coronary angiography for assessment of fractional flow reserve (FFR)…
- Trial name
- NCT07018778
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Kerckhoff Klinik
Coronary Artery Disease(CAD)
Comparison of Diagnostic Accuracy Between XTR004 PET MPI and the Composite Index of Quantitative Coronary Angiography (QCA) and Fractional Flow Reserve (FFR)
The primary objective of this study is to evaluate the effectiveness of visual reading in XTR004 PET myocardial perfusion imaging (MPI) for detecting restrictive stenosis, using quantitative coronary angiography (QCA) and…
- Trial name
- NCT07439133
- Testing
- XTR004
- Where
- 5 sites in China
- Volunteers
- 395 people
- Sponsor
- Sinotau Pharmaceutical Group
Ischemic Heart Disease
Myocardial Perfusion Imaging by 15O-H2O PET/CT
The trial will include 5000 patients with evident or suspected ischemic heart disease refered to Department of Nuclear Medicine \& PET Centre, Aarhus University Hospital, for perfusion imaging by 15O-H2O PET/CT scan of the heart…
- Trial name
- NCT04451551
- Where
- Denmark
- Volunteers
- 5,000 people
- Sponsor
- University of Aarhus
Transthyretin Cardiac Amyloidosis
Effect of Trimetazidine on Coronary Flow in Transthyretin Cardiac Amyloidosis
The goal of this clinical trial is to learn if trimetazidine can improve blood flow in the heart in adults with transthyretin cardiac amyloidosis (ATTR-CM).
- Trial name
- TACT-TTR (NCT07836699)
- Testing
- Trimetazidine
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Fábio Fernandes
Myocardial Blood Flow Reserve, Mechanical Dyssynchrony
Mechanical Dyssynchrony and Microvascular Dysfunction by SPECT
The project is aimed at studying the feasibility of mechanical dyssynchrony of the left ventricle of the heart, determined by SPECT (gated MPI), as well as its stress-induced dynamics, in the evaluation of patients with coronary…
- Conditions
- Myocardial Blood Flow Reserve, Mechanical Dyssynchrony, Coronary Arterial Disease (CAD)
- Trial name
- MD&MD (NCT06969547)
- Testing
- dynamic SPECT (two-day rest/stress protocol), gated myocardial perfusion imaging, blood sampling
- Where
- Russia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Microvascular Angina
Microvascular Angina Intervention With Compound Danshen Dripping Pill (MAIDS)
Coronary microvascular disease (MVD) refers to exertional angina or myocardial ischemia caused by abnormal structure and/or function of precoronary arterioles and arterioles under the action of various pathogenic factors.
- Trial name
- MAIDS (NCT06092736)
- Testing
- Compound Danshen Dropping Pills
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qilu Hospital of Shandong University
Coronary Artery Disease
A Head-to-Head Comparison of A New Perfusion Tracer, 99mTc-4BOH vs. 13N-NH3 to Evaluate Diagnostic Efficacy of Ischemic Heart Disease
The objective of the study is to assess the diagnostic efficacy (specificity and sensitivity) of 99mTc-4BOH SPECT myocardial perfusion imaging (MPI) compared to 13N-ammonia PET MPI in the detection of significant coronary artery…
- Trial name
- NCT06980194
- Testing
- 99mTc-4BOH SPECT myocardial perfusion imaging, 13N-ammonia PET myocardial perfusion imaging
- Volunteers
- 300 people
- Sponsor
- China National Center for Cardiovascular Diseases