Clinical trials: Musculoskeletal Pain
Painful Unilateral Femorotibial Knee Osteoarthritis of Any Etiology
Trial Comparing Botulin Toxin Versus Hyaluronic Acid by Intra-articular Injection for the Treatment of Painful Knee Osteoarthritis
In France, osteoarthritis affects about 10 million people and knee osteoarthritis represents 35% of cases. It is thought that more than 2.5 million people older than 65 years have knee osteoarthritis.
- Trial name
- GOTOX (NCT02832713)
- Testing
- Botulinum toxin A ( BoNT-A), Hyaluronic acid (HA)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Chronic Widespread Pain, Fibromyalgia
Efficacy and Safety of IGN-ES001 in Chronic Widespread Pain With or Without Fibromyalgia
This is a randomized, double-blind, placebo-controlled exploratory trial to investigate efficacy and safety of food supplement IGN-ES001 in patients with chronic widespread pain (CWP) with or without fibromyalgia (FM).
- Trial name
- NCT03058224
- Testing
- IGN-ES001, Parol 500 mg Tablets (acetaminophen)
- Where
- 23 sites in Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- IgNova GmbH
Fibromyalgia
Quetiapine (Seroquel XR) for the Treatment of Fibromyalgia: a Clinical and Mechanistic Pilot Study
This is a double-blind, randomized, placebo-controlled trial measuring the impact of quetiapine on clinical and experimental measures of pain in fibromyalgia and its biochemical correlates.
- Trial name
- NCT00983320
- Testing
- quetiapine
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Université de Sherbrooke
Frozen Shoulder, Adhesive Capsulitis
Comparison of Niel-Asher and Spencer Techniques in Frozen Shoulder Patients
This study aims to compare the effectiveness of two manual therapy techniques-Niel-Asher Technique and Spencer Technique-when combined with conventional physiotherapy in treating patients with frozen shoulder (adhesive…
- Trial name
- NCT07080060
- Testing
- Niel-Asher Technique, Spencer Technique
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Breast Neoplasm Female, Arthralgia
Trial of Oral Hyaluronic Acid for the Prevention of Aromatase Inhibitor-Associated Arthralgias
This is a single center, double-blinded, placebo-controlled, randomized Phase II trial to determine whether oral hyaluronic acid will prevent aromatase inhibitor (AI)-associated arthralgias.
- Trial name
- NCT03384095
- Testing
- Hyaluronic Acid (HA)
- Where
- 4 sites in United States
- Sponsor
- Erin Newton
Adhesive Capsulitis
Effect of HVLA vs MET on Shoulder Mobility and Pain in Adhesive Cpsulitis
This study compared the effects of High-Velocity Low-Amplitude (HVLA) thrust and Post-Isometric Relaxation Muscle Energy Technique (PIR-MET) on pain and shoulder mobility in patients with adhesive capsulitis.
- Trial name
- HVLA-MET-AC (NCT07600372)
- Testing
- High Velocity Low Amplitude Thrust, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Green International University
Adhesive Capsulitis
Additional Effects of Thoracic Spine Mobilization Combined With Glenohumeral Joint Mobilization on Pain, Range of Motion, and Functional Disability in Adhesive Capsulitis
Adhesive capsulitis is a debilitating shoulder condition characterized by pain, restricted range of motion (ROM), and significant functional limitations.
- Trial name
- NCT07328295
- Testing
- Thoracic spine mobilization with Glenohumeral joint mobilization, Glenohumeral joint mobilization only
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Foundation University Islamabad
Anesthesia, Local, Anesthesia
Regional Anesthesia in Pediatric Orthopaedic Patients
To identify the benefits from regional anesthesia use as pain management in the pediatric population by delineating the differences in efficacy of continuous nerve blockade versus single-shot techniques after pediatric…
- Conditions
- Anesthesia, Local, Anesthesia, Orthopedic Disorder
- Trial name
- NCT04669145
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Ochsner Health System
Osteoarthritis of Knee, Knee Pain Chronic
Computer-guided Action Planning to Support Physical Activity (CAPPA) for Employees With Chronic Knee Symptoms
The goal of this clinical trial is to learn if a brief health coaching intervention based on an approach known as brief action planning + Fitbit can increase physical activity in employees with chronic knee symptoms who work for…
- Trial name
- CAPPA (NCT06734052)
- Testing
- CAPPA, Health education
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Marquette University
Cervicogenic Headache
Effectiveness of a Novel Device for Cervical Training in Cervicogenic Headache.
The purpose of this study is to evaluate the clinical results in cervical spine range of motion, endurance deep cervical muscles, headache impact and physical activity enjoyment by a training protocol with the new device for…
- Trial name
- NCT05479149
- Testing
- Training protocol with the cervical device for treatment (CDAT)., Conventional training protocol
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universitat Internacional de Catalunya
Lumbar Spondylosis
Study Evaluating the Safety and Feasibility of Platelet-rich Plasma to Treat Facetogenic Low Back Pain
This study is being done to assess the safety of using the Angel Concentrated Platelet Rich Plasma System to process Platelet Rich Plasma (PRP) to treat arthritis of the low back (lumbar spondylosis).
- Trial name
- NCT05250947
- Testing
- Angel® Concentrated Platelet Rich Plasma System, Platelet Rich Plasma
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Matthew Pingree
Fibromyalgia
Prospective Evaluation of RINCE to Reduce Fibromyalgia Effects - 202
The purpose of this study is to test the safety and efficacy of a noninvasive cortical electrostimulation therapy known as "Reduced Impedance Noninvasive Cortical Electrostimulation" (RINCE) in the treatment of pain associated…
- Trial name
- PERRFECT-202 (NCT02613949)
- Testing
- RINCE
- Where
- 4 sites in United States
- Volunteers
- 45 people
- Sponsor
- Cerephex Corporation
Lumbar Disc Herniation, Mindfulness Meditation
Mindfulness-based Psychoeducation in Patients With Lumbar Disc Herniation
This study aimed to investigate the effect of mindfulness-based psychoeducation on mindfulness, automatic thoughts, and pain beliefs in patients with lumbar disc herniation.
- Trial name
- MBPE (NCT07683884)
- Testing
- Experimental Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Giresun University
Osteoarthritis
The Effect of Mobilization With Movement on Pain and Function Among Patients With Knee Osteoarthritis
Osteoarthritis (OA) is the most prevalent form of arthritis and is reported to be the most important reason behind functional disability and musculoskeletal disorders among aged individuals.
- Trial name
- NCT02865252
- Testing
- MWM Treatment
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Widspread Chronic Pain, Fibromyalgia
The Effect of Vagus Nerve Stimulation on Pain and Functional Activities in Individuals With Chronic Widespread Pain
The goal of this clinical trial is to examine the effect of vagus nerve stimulation (VNS) on chronic, widespread pain in adults.
- Trial name
- NCT07080749
- Testing
- Vagal nerve stimulation through deep exhalation exercise, Vagal nerve stimulation through ear electrical stimulation, No intervention (observational study)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Georgia
Joint Pain, Musculoskeletal Pain
IDEA-033 Open Label Study
The main aim of the study is to evaluate safety, efficacy, compliance, and usage of epicutaneously applied IDEA-033 in joint / musculoskeletal pain or soft tissue inflammation.
- Conditions
- Joint Pain, Musculoskeletal Pain, Stiffness, Soft Tissue Inflammation in Designated Target Area(s)
- Trial name
- NCT00372333
- Testing
- IDEA-033
- Where
- Germany
- Volunteers
- 491 people
- Sponsor
- IDEA AG
Adhesive Capsulitis, Shoulder
Effectiveness of Focal Vibration in Shoulder Pathology
We hypothesize that focal vibration therapy will reduce pain, increase the mobilization of the glenohumeral joint, and will improve functionality in patients with adhesive capsulitis.
- Trial name
- FVinAC (NCT05214547)
- Testing
- Focal VibrationTherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bitlis Eren University
Osteoarthritis, Knee, Pain, Knee
Study of Resiniferatoxin for Knee Pain in Moderate to Severe Osteoarthritis
This study evaluates the safety of resiniferatoxin in patients with moderate to severe knee pain due to osteoarthritis.
- Trial name
- NCT03542838
- Testing
- Resiniferatoxin, Saline
- Where
- 4 sites in United States
- Volunteers
- 94 people
- Sponsor
- Sorrento Therapeutics, Inc.
Neck Pain, Neck Pain Musculoskeletal
Comparing Deep and Superficial Dry Needling for Neck Pain: An Ultrasound and EMG Study
The purpose of this clinical trial is to compare the effects of deep versus superficial dry needling (DN) on the ultrasound and electromyographic (EMG) characteristics of myofascial trigger points (MTrPs) in the upper trapezius…
- Trial name
- NCT07637552
- Testing
- Deep Dry Needling and Superficial Dry Needling
- Where
- Saudi Arabia
- Volunteers
- 44 people
- Sponsor
- Qatif Central Hospital
Hip Osteoarthritis
Clinical Pilates in Hip Osteoarthritis: A Randomised Controlled Trial
The aim of this study is to investigate the effect of a clinical Pilates exercise program on reducing symptoms in individuals with hip osteoarthritis.
- Trial name
- NCT06783452
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Izmir Katip Celebi University