Clinical trials: Musculoskeletal Diseases or Conditions
Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis
Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty
This long-term outcomes study is designed to collect safety and efficacy data on designated, commercially available, hip arthroplasty products.
- Conditions
- Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis, Femur Head Necrosis, Congenital Dislocations
- Trial name
- NCT02230826
- Where
- 13 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Corin
Acute Leukemias of Ambiguous Lineage, Bacterial Infection
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation
This randomized phase III trial studies how well levofloxacin works in preventing infection in young patients with acute leukemia receiving chemotherapy or undergoing stem cell transplant.
- Conditions
- Acute Leukemias of Ambiguous Lineage, Bacterial Infection, Diarrhea, Fungal Infection
- Trial name
- NCT01371656
- Testing
- levofloxacin
- Where
- 84 sites in United States, Canada
- Volunteers
- 624 people
- Sponsor
- Children's Oncology Group
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Muscle Weakness, Rehabilitation
Efficacy of Different Treatments for the Intensive Care Unit Acquired Weakness
Experimental study that has how to compare the efficacy between conventional rehabilitation, transcutaneous electrostimulation or early mobilization to reduce the time needed to reverse the muscle weakness evaluated by the muscle…
- Trial name
- NCT04613908
- Testing
- neuro muscular electro stimulation, Early Mobilization protocol, standard care or usual rehabilitation
- Volunteers
- 18 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Systemic Sclerosis, Systemic Lupus Erythematosus
Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders
OBJECTIVES: I. Determine the safety and long term complications of total body irradiation in combination with cyclophosphamide, anti-thymocyte globulin, and autologous CD34-selected peripheral blood stem cell (PBSC)…
- Conditions
- Systemic Sclerosis, Systemic Lupus Erythematosus, Dermatomyositis, Juvenile Rheumatoid Arthritis
- Trial name
- NCT00010335
- Testing
- Stem Cell Transplantation, CD34 selection
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Fred Hutchinson Cancer Center
Musculoskeletal Diseases or Conditions
Orthobiological Therapies in Musculoskeletal Disorders
To evaluate the clinical and functional effects of using orthobiological therapies (hyaluronic acid, platelet-rich plasma, bone marrow aspirate, nanofat, among others) in the treatment of various musculoskeletal diseases in…
- Trial name
- PROREGEN (NCT07434115)
- Testing
- PRP injection, Bone Marrow Concentrate (BMAC), Hyaluronic Acid (Viscosupplementation)
- Where
- Brazil
- Volunteers
- 300 people
- Sponsor
- PROREGEN
Pain, Postoperative, Excavatum, Pectus
Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery
This will be a prospective observational study to determine the association between specific genotypes, epigenetics, behavioral, social and biological factors, with the phenotypes, defined by pain perception, postoperative pain…
- Conditions
- Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
- Trial name
- NCT04031716
- Testing
- Meditation
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Herniated Disc, Intervertebral Disc Displacement
Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy
The hypothesis of this study is that Gabapentin or Amitriptyline has no role in preemptive analgesia to reduce postoperative pain after lumbar diskectomies.
- Trial name
- NCT01014520
- Testing
- Gabapentin , Amitriptyline
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Tabriz University
Osteoarthritis of the Shoulder, Osteoarthritis of the Hip
Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Patients With OA of the Shoulder or Hip
This is an open-label study to compare systemic exposure to triamcinolone acetonide following a dose of extended-release FX006 or immediate-release TAcs (triamcinolone acetonide suspension) in patients with osteoarthritis of the…
- Trial name
- NCT03382262
- Testing
- FX006 32 mg, TAcs 40 mg
- Where
- 6 sites in United States
- Volunteers
- 55 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Chronic Pain, Disability Physical
Physical Therapy to Treat Chronic Pain in Survivors of Trauma
This study will assess the effects of physical therapy (PT) for individuals who are survivors of trauma (SOT) and have chronic pain.
- Trial name
- NCT03933189
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Vermont
Ledderhose Disease
Ledderhose Disease: Radiotherapy or Not?
The aim of the LedRad trial is to determine the efficacy and durability of radiotherapy as treatment for patients with Ledderhose disease and to compare this to the natural course of Ledderhose disease.
- Trial name
- LedRad (NCT03507010)
- Testing
- Radiotherapy
- Where
- Netherlands
- Volunteers
- 84 people
- Sponsor
- University Medical Center Groningen
Rotator Cuff Syndrome, Rotator Cuff Tears
Profiling the RCRSP Patient: a Pain Phenotype Classification Algorithm
The aim of this study is to collect a sum of different characteristics that have been mentioned previously in people presenting with RCRSP and by clustering them to create a phenotype system which may assist the individualisation…
- Conditions
- Rotator Cuff Syndrome, Rotator Cuff Tears, Rotator Cuff Tendinosis, Rotator Cuff Impingement
- Trial name
- NCT05817578
- Testing
- Quantitative Sensory Testing / Dynamometry / Goniometry
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Osteonecrosis
Randomized Clinical Trial for the Treatment of Osteonecrosis of the Femoral Head
Femoral head avascular necrosis is a relatively common disease (10,000 - 20,000 yearly new United States of America cases) characterized by ischemic cell necrosis in a hip proximal epiphysis area frequently requiring total Hip…
- Trial name
- AVN-13 (NCT01892514)
- Testing
- core decompression
- Where
- 3 sites in Italy
- Volunteers
- 104 people
- Sponsor
- Istituto Ortopedico Rizzoli
Cough, Myalgia
Clinical Evaluation of QFlu Combo Test
Currently effective antivials for influenza treatment are two influenza viral neuraminidase inhibitors, oseltamivir (Tamiflu) and zanamivir (Relenza).
- Conditions
- Cough, Myalgia, Nasal Obstruction, Sore Throat
- Trial name
- QFlu (NCT01506583)
- Where
- 3 sites in United States
- Volunteers
- 506 people
- Sponsor
- Cellex, Inc.
Laryngomalacia, Acid Reflux
In Infants With Laryngomalacia, Does Acid-Blocking Medication Improve Respiratory Symptoms?
All neonates, ages 0 to 4 months, presenting to LPCH pediatric ENT clinic for airway difficulties or stridor will be screened for inclusion.
- Conditions
- Laryngomalacia, Acid Reflux, Stridor
- Trial name
- NCT02700087
- Testing
- ranitidine or famotidine
- Where
- United States
- Sponsor
- Stanford University
Tennis Elbow
Eccentric Exercise or Radiofrequent Microtenotomy as Treatment of Lateral Epicondylalgia
The aim is to study the effects related to function and pain during eccentric exercise and surgery with radiofrequency microtenotomy as post-surgical rehabilitation, compared with only eccentric exercise, in patients with lateral…
- Trial name
- NCT02304952
- Testing
- Radiofrequency microtenotomy, Eccentric exercise, Arthrocare Topaz MicroDebrider
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- St Goran's Hospital
Pain, Weakness
Clinical Trial of CoQ10 for Mild-to-Moderate Statin-Associated Muscle Symptoms
This study will evaluate whether a dietary supplement, coenzyme Q10 (CoQ10), will improve muscle symptoms, such as muscle aches, pains, cramps, and/or weakness, which are experienced by some individuals who use statin medications.
- Conditions
- Pain, Weakness, Cramps, Myalgia or Myositis Nos
- Trial name
- NCT01032993
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Catherine Buettner
Osteoporosis
Study of Low Bone Mass in Premenopausal or Perimenopausal Women
OBJECTIVES: I. Determine the possible causes of bone loss in premenopausal or perimenopausal women.
- Trial name
- NCT00005101
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Intensive Care Unit, Muscle Weakness
Use of Neuromuscular Electrostimulation (NMES) for Treatment or Prevention of ICU-Associated Weakness
The purpose of this study is to investigate whether neuromuscular electrostimulation (NMES) will decrease ICU-associated weakness.
- Trial name
- NMES (NCT00709124)
- Testing
- Neuromuscular Electrostimulation (NMES) CareStim Muscle Stimulation Device (Care Rehab; McLean, VA)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johns Hopkins University
Low Back Pain
A Randomized, Equivalence Trial of Percutaneous Lumbar Adhesiolysis and Caudal Epidural Steroid Injections
The purpose of this study is to: evaluate the effectiveness of percutaneous epidural adhesiolysis in managing chronic low back and/or lower extremity pain in patients without post lumbar surgery syndrome or spinal stenosis and…
- Trial name
- NCT01053273
- Testing
- Caudal Epidural Injection, percutaneous adhesiolysis
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah