Clinical trials: Muscle Weakness
Diabetes Mellitus, Type 2, Polyneuropathy Diabetes
Resistance Training in Patients With Diabetic Neuropathy
This is a population-based study of type 2 diabetes patients with and without neuropathy recruited from the Danish National Type 2 Diabetes cohort (DD2).
- Conditions
- Diabetes Mellitus, Type 2, Polyneuropathy Diabetes, Diabetes Complications, Diabetic Peripheral Neuropathy
- Trial name
- NCT03252132
- Testing
- 12-week resistance training
- Where
- Denmark
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Danish Pain Research Center
Stroke Sequelae, Gait, Hemiplegic
ACTive Exoskeleton for Unilaterally-Assisted Locomotion (ACTUAL)
Walking difficulties are common symptoms after stroke, significantly reducing quality of life. Walking recovery is therefore one of the main priorities of rehabilitation.
- Trial name
- ACTUAL (NCT06061601)
- Testing
- Exoskeleton stroke group
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Core Muscle Weakness, Postural Control Deficit
"CORE Training for Musculoskeletal Health: A Study on Adaptive Exercise Protocols"
This study aims to evaluate the effects of an adaptive core training protocol that integrates core stability, core strength, and high-intensity core power exercises on muscle activation, hypertrophy, balance, and quality of life.
- Conditions
- Core Muscle Weakness, Postural Control Deficit, Trunk Stability Impairment, Functional Performance Limitation
- Trial name
- RCT-EMG-US-QoL (NCT07025395)
- Testing
- - Core Training Protocol, Control Group Core Routine
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ioannis Tsartsapakis
Upper Extremity Paresis
PNF Strengthening and De-lorme and Watkins Exercises on Upper Extremity Function and Strength in Stroke Patients
The aim of this study is to evaluate the effects of proprioceptive neuromuscular facilitation strengthening exercises and de-Lorme and Watkins exercises program in stroke patients with upper limb weakness in chronic stroke…
- Trial name
- NCT05904795
- Testing
- PNF strengthening exercises, de-lorme and watkins exercises
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Primary Mitochondrial Disease
Natural History Study of Mitochondrial Myopathy
The goal of this observational study is to develop and validate tools to measure disease course in patients with primary mitochondrial myopathy (PMM).
- Trial name
- NCT05250375
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Muscle Weakness Condition
Low Resistance Venous Blood Flow Restriction Training (LR-VBFRT) on Biceps Brachii Muscle Performance
Resistance training has been widely recognized as an effective stimulus for increasing skeletal muscle size and strength. This study intends to compare the effects of high resistance training without blood flow restriction and…
- Trial name
- NCT04181671
- Testing
- Low Resistance training with venous blood flow restriction, High Resistance training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Traumatic and/or Non-traumatic Brain Injury
Assessing Special Features of Impaired Gait After Acquired Brain Injury With an Instrumented Treadmill
Hemiparetic gait following acquired brain injury (ABI) is grossly characterized by decreased speed of walking, increased stance time on the unaffected side, and decreased stance time on the affected side.These abnormalities are…
- Trial name
- NCT01413321
- Where
- Israel
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Fall Injury, Postural; Defect
Conscious Movement Processing, Postural Stability and Muscle Efficiency in Older Adults
This study aims to address critical knowledge gaps by investigating the effects of trait conscious movement processing propensity on real-time (state) conscious movement processing propensity, postural stability, and muscle…
- Conditions
- Fall Injury, Postural; Defect, Old Age; Debility
- Trial name
- NCT05630911
- Testing
- Standing tasks with different task difficulty
- Where
- China
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Lower Urinary Tract Symptoms, Posture Disorders in Children
Examination of Trunk and Lower Extremity Biomechanics in Children With LUTD.
This study aimed to examine trunk and lower extremity biomechanics among children with lower urinary tract dysfunction (LUTD). It was targeted to pioneer including biomechanical changes into treatment if detected in the trunk and…
- Conditions
- Lower Urinary Tract Symptoms, Posture Disorders in Children, Muscle Weakness Condition, Urinary Incontinence in Children
- Trial name
- NCT05299827
- Testing
- The same evaluation methods were used for both groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Pelvic Floor Muscle Weakness, Pelvic Pain
Movement-Based Pelvic Health Education for Women in Underserved Communities
It is essential to provide the community with evidenced-based care to optimize healthcare outcomes; more specifically, women in underserved communities undergoing health disparities in rehabilitation.
- Trial name
- PHEd (NCT05569694)
- Testing
- Movement-based pelvic health education
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Intensive Care (ICU) Myopathy
Biomechanical Properties in Intensive Care Unit (ICU) Survivors 12-month After Discharge
Intensive care unit (ICU) admission is associated with muscle weakness and ICU survivors report persevering limitation of physical capacity for years after discharge.
- Trial name
- NCT01364714
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Musculoskeletal Status, Muscle Weakness
Use of Jumping Mechanography as a Method to Assess Musculoskeletal Status in Older Adults
Decline in muscle function may increase risk of hip fracture and decrease quality of life. Different tests are currently used to measure muscle function but they do not work for all individuals.
- Trial name
- NCT00596089
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Stroke, Hemiparesis
Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke
This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.
- Trial name
- NCT06598150
- Testing
- Shoulder Abduction
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Neostigmine, Neuromuscular Blocking Agents
Reversal of Moderate or Superficial Neuromuscular Blockade Induced by Cisatracurium
The administration of acetylcholinesterase inhibiting agents (such as neostigmine) has been used to reverse the muscle paralysis induced by non-depolarizing neuromuscular blocking agents.
- Conditions
- Neostigmine, Neuromuscular Blocking Agents, Muscle Weakness
- Trial name
- NCT04920682
- Testing
- Reversal of moderate neuromuscular blockade, Reversal of superficial neuromuscular blockade, Two-step reversal
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Heart Failure, Sarcopenia
Multivariate Biomarker Study for Sarcopenia in Heart Failure
In the United Kingdom, heart failure (HF) affects about 900,000 people with 60,000 new cases annually. Up to 60% of people living with HF also experience sarcopenia, known as loss of muscle mass and strength.
- Conditions
- Heart Failure, Sarcopenia, Muscle Weakness, Body Weight
- Trial name
- NCT06217640
- Testing
- Dual X Ray Absorptiometry
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Pelvic Floor Disorders, Pelvic Floor Muscle Weakness
Association Between Physical Activity Level ，Overall Muscle Strength and Pelvic Floor Muscle Function in Women.
In this study, it is assumed that grip strength is associated with pelvic floor muscle strength. And the outcome of pelvic floor function can be predicted by referring to the status of pelvic floor muscle strength through the…
- Trial name
- NCT05318768
- Where
- China
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Muscle Weakness
Functional Change With MMS
Evaluate the safety and efficacy of magnetic muscle stimulation (MMS) of abdominal muscle.
- Trial name
- FMS (NCT04506502)
- Testing
- The ZELTIQ System
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Sarcopenia, Aging
Reducing Falls With Progressive Resistance Training for the Oldest Old Adults With Reduced Muscle Strength
This study will investigate the effects of 12 months of high-intensity progressive resistance training compared with a control group on fall-rate in older adults with reduced muscle strength.
- Trial name
- ReFit (NCT05691166)
- Testing
- High-intensity progressive resistance training, Written physical activity guidance
- Where
- Norway
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Muscle Weakness Condition, Therapy Effect
Vibrational-proprioceptive Resistance Exercise Training Versus Neuromuscular Electrical Stimulation Training in Elderly People With Muscle Weakness
Study the structural behaviours of weak muscle of elderly and evaluate the efficiency of two different types of training.
- Trial name
- MOBIL (NCT01679977)
- Testing
- Vibrational-proprioceptive Resistance Exercise Training, Neuromuscular Electrical Stimulation Training
- Where
- 2 sites in Austria, Slovakia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation
Muscle Weakness, Muscle Loss
Power Training on Muscle Quality and Functional Capacity in Women Aged 65-75.
Muscle power training has proven to be an effective intervention to prevent sarcopenia and frailty in old people. In the last decade, new concepts related to the functionality of old people have been generated, such as muscle…
- Trial name
- NCT04315662
- Testing
- Muscle power training with velocity loss (VL) of 10%, Muscle power training with velocity loss (VL) of 30%
- Where
- Colombia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universidad del Valle, Colombia