Clinical trials: Muscle Mass
Clavicle Fracture
Crossed Education in Relation to Muscle Mass in Patients Operated of Clavicular Fracture
The immobilization process after an operation or injury in the upper extremity causes a loss of muscle mass and strength of 0.2% and 1.3% per day, respectively.
- Trial name
- crossed1 (NCT05810129)
- Testing
- concentric-eccentric strength training, standard physical therapy
- Where
- Chile
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Healthy Adult Participants
Yeast Protein for Muscle Mass
Protein supplementation is said to be one of the cost-efficient and practical strategies to meet protein needs for growth and exercise, and can help maximize muscle gain from resistance exercise.
- Trial name
- NCT07561619
- Testing
- Yeast Protein, Resistance Training Exercises, Whey Protein
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Marfan Syndrome
Cardiorespiratory and Muscular Rehabilitation of Children and Young Adults With Marfan Syndrome.
Marfan syndrome (MFS) is a rare genetic disease (1/5000) characterized by the association of ocular impairment, cardiovascular disease and musculoskeletal disease.
- Trial name
- Marfanpower (NCT03236571)
- Testing
- Rehabilitation program
- Where
- France
- Volunteers
- 28 people
- Sponsor
- University Hospital, Toulouse
Obesity, Overfeeding
Overeating Different Fats and Influence on Muscle Mass and Body Fat Accumulation
To investigate metabolic and molecular response to fatty acid-specific overfeeding in overweight subjects, in relation to changes in ectopic fat, lean tissue mass and insulin sensitivity
- Conditions
- Obesity, Overfeeding, Muscle Mass, Body Composition
- Trial name
- LIPOGAIN-2 (NCT02211612)
- Testing
- PUFA-group, SFA-group
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Muscle Loss in Elderly
The Effects of Resistance Training and Protein Supplementation in Healthy Elderly Men and Women.
The main objective of this study is to examine the effects of resistance type exercise training combined with nutritional support on body composition and muscle characteristics in healthy elderly men and women.
- Trial name
- NCT01004588
- Testing
- Protein drink
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenia, Muscle Atrophy
Concurrent Assessment of Skeletal Muscle Mass and Synthesis/Breakdown in Old Age
This study involves minimally-invasive techniques to measure muscle mass, muscle protein breakdown and synthesis simultaneously in older age.
- Trial name
- NCT04114383
- Testing
- D3-Creatine, Deuterium Oxide, D3-3-methylhistidine
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Weight Loss, Ovarian Carcinoma
Skeletal Muscle Energy Metabolism in Women With Weight Loss and Ovarian and/or Endometrial Cancer With Weight Loss
the aim is to study skeletal muscle metabolism alterations métaboliques associated with weight loss in women with ovarian and/or endometrial cancer according to BMI.
- Conditions
- Weight Loss, Ovarian Carcinoma, Endometrial Carcinoma
- Trial name
- METERMUS-IMC (NCT03027479)
- Testing
- Samples
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Tours
Head and Neck Cancer, Radiotherapy; Adverse Effect
Monitoring Skeletal Muscle Mass Using CBCT in Patients With H&N Cancer Undergoing Chemoradiotherapy
Chemoradiotherapy is the standard treatment for unresectable locally advanced head and neck cancer (HNC). However, malnutrition is present in 44-88% HNC patients during chemoradiotherapy, which leads to loss of skeletal muscle…
- Trial name
- MELINOE (NCT05126095)
- Testing
- Radical radiotherapy
- Where
- China
- Volunteers
- 135 people
- Sponsor
- Guangdong Provincial People's Hospital
Knee Osteoarthritis
Unicondylar- or Total Knee Replacement? Patient Satisfaction, Function and Muscle Mass
Patients with medial gonarthritis are randomised to a unicompartmental or a total knee replacement. Primary outcome: Thigh muscle cross sectional area and radiological attenuation measured by CT Secondary aims: functional tests…
- Trial name
- UKA or TKA? (NCT02563756)
- Testing
- Unicompartmental knee replacement, Total knee replacement
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Aging
Dietary Interventions for Muscle Mass
Dietary intervention to prevent sarcopenia in elderly people. The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate…
- Trial name
- NCT01145131
- Testing
- Intact or minced beef meat
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Mortality, Muscle Loss
Mortality and Muscle Mass Loss in Critically Ill Patients.
The aim of the study is to monitor changes in muscle mass in critically ill patients and to verify whether a decrease in muscle mass of ≥10% during the first 7 days of hospitalization is associated with increased 28-day…
- Trial name
- MUSIC 2 (NCT07280039)
- Where
- Czechia
- Volunteers
- 386 people
- Sponsor
- Brno University Hospital
Cachexia, Neoplasms
Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Muscle mass loss is a common adverse effect of cancer. Muscle mass loss occurs with or without reduction in body weight. Cancer cachexia (CC) is the involuntary loss of body weight of >5% within 6 months and it occurs in 50-80%…
- Conditions
- Cachexia, Neoplasms, Exercise, Metabolism
- Trial name
- PANACEA (NCT05307367)
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Muscle Mass
Strength Training Response of Muscle in GLP-1 Users
GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function.
- Trial name
- STRONG-GLP (NCT07104539)
- Testing
- Strength Training, Wait first, then strength training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Muscle Mass, Muscle Strength
Vitality Acupunch Exercise Program for Older Adults With Sarcopenia
This project was aimed to test the effects of a six-month VA program on the muscle mass, muscle strength, and quality of sleep of institutional older adults with sarcopenia.
- Conditions
- Muscle Mass, Muscle Strength, Sleep Quality
- Trial name
- VA (NCT04535336)
- Testing
- Vitality acupunch (VA) exercise program, Control
- Where
- Taiwan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Sporadic Inclusion Body Myositis
Efficacy and Safety of Bimagrumab/BYM338 at 52 Weeks on Physical Function, Muscle Strength, Mobility in sIBM Patients
This study evaluated the efficacy, safety and tolerability of multiple doses of bimagrumab/BYM338 vs placebo, when administered intravenously (i.v.), on physical function, muscle strength, and mobility in patients with sporadic…
- Trial name
- RESILIENT (NCT01925209)
- Testing
- BYM338/bimagrumab
- Where
- 38 sites in United States, Australia and 8 more
- Volunteers
- 251 people
- Sponsor
- Novartis Pharmaceuticals
Hematologic Diseases, Acute Myeloid Leukemia
Muscle Dysfunction in Patients With Haematological Diseases
PURPOSE: To evaluate the prevalence and prognostic value of sarcopenia in patients diagnosed with hematological cancer diseases.
- Conditions
- Hematologic Diseases, Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Myelodysplastic Syndromes
- Trial name
- NCT05150561
- Where
- Denmark
- Volunteers
- 216 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Diabetes Mellitus, Type 2
Krill Oil and Muscle Weakness in Type 2 Diabetes
The age-related loss of muscle mass and function, sarcopenia, has several deleterious effects, such as a reduction in the quality of life and an increase in the incidence of falls, often leading to hospitalisation.
- Trial name
- KRIMD (NCT04943523)
- Testing
- Krill Oil, Vegetable Oil
- Where
- Kuwait
- Volunteers
- 150 people
- Sponsor
- Dasman Diabetes Institute
Pulmonary Rehabilitation, Sarcopenia
Pulmonary Rehabilitation in Advanced Non-small Cell Lung Cancer Patients
Lung cancer (LC) is usually diagnosed in advanced stages and continues to be the leading cause of cancer related deaths worldwide.
- Conditions
- Pulmonary Rehabilitation, Sarcopenia, Quality of Life
- Trial name
- NCT02978521
- Testing
- Pulmonary rehabilitation
- Where
- Mexico
- Volunteers
- 94 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Bladder Cancer
The Difference of Two Year Recurrence Rate According to Anesthetic Method During Transurethral Resection of Bladder Mass in Patients With Non-muscle Invasive Bladder Cancer: Prospective, Randomized, Clinical Phase II Study
The investigators compare the recurrence rate difference between two years after transurethral resection of the bladder tumor according to the method of anesthesia. Anesthetic methods are general anesthesia and spinal anesthesia.
- Trial name
- NCT03597087
- Testing
- Anesthesia before transurethral resection of the bladder tumor, Anesthesia
- Where
- South Korea
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Spinal Muscular Atrophy, Merosin Deficient Congenital Muscular Dystrophy
Fat and Glucose Metabolism in Fed and Fasted State in Patients With Low Skeletal Muscle Mass
In a study from 2003 the investigators showed that adult patients with very low skeletal muscle mass (spinal muscular atrophy (SMA) type II, Duchenne muscular dystrophy, congenital muscular dystrophy) are prone to develop…
- Trial name
- NCT03970135
- Testing
- Fasting
- Where
- Denmark
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet