Clinical trials: Muscle Health
Type 1 Diabetes
Skeletal Muscle Health in Children With Type 1 Diabetes
The purpose of this research study is to find out if Type 1 Diabetes (T1D) affects skeletal muscle health and if we can improve glycemic control by improving skeletal muscle health.
- Trial name
- NCT04288063
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Duke University
Open Heart Surgery, Cardiovascular Disease
The Effect of Neurophysiological Facilitation Techniques on Health Parameters in Early Stages After Open Heart Surgery
In this study, researchers aimed to investigate effects of neurophysiological facilitation on functional capacity and respiratory parameters of patients who underwent open heart surgery.
- Conditions
- Open Heart Surgery, Cardiovascular Disease, Physiotherapy
- Trial name
- NCT06551714
- Testing
- Phase 1 cardiac rehabilitation, Neurophysiological facilitation techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Dogus Universitesi
Smoking Cessation, Body Composition, Beneficial
The Effect of Cigarette Smoking / Smoking Cessation on Skeletal Muscle Mass, Strength and Functional Capabilities
Tobacco smoke is probably the single most significant source of toxic chemicals that humans are exposed to. Smoking is associated with a variety of pathological conditions such as cardiovascular and pulmonary diseases.
- Conditions
- Smoking Cessation, Body Composition, Beneficial, Muscle Weakness
- Trial name
- NCT02128048
- Testing
- Assessment of body composition and muscle function
- Where
- Israel
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Healthcare Workers, Musculoskeletal Pain
Effects of Telerehabilitation-Based Clinical Pilates Exercises on Health Care Workers
Musculoskeletal disorders can cause a decrease in employees' work continuity and job performance. During their working hours, healthcare workers stand for long periods of time, sit in wrong positions, actively use their upper…
- Trial name
- NCT06772948
- Testing
- Asynchronised group, Synchronized group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biruni University
Duchenne Muscular Dystrophy
Hydrotherapy in Duchenne Muscular Dystrophy (DMD)
The goal of this clinical trial aims to establish if there are meaningful benefits to providing a hydrotherapy service for young people with Duchenne muscular dystrophy (DMD). The main aims are to: 1.
- Trial name
- NCT06445985
- Testing
- Hydrotherapy
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Forearm Muscle Strength, Radial Bone Health
SUPERVISED RESISTANCE AND WEIGHT-BEARING EXERCISE IN INSTITUTIONALIZED OLDER ADULTS
This quasi-experimental controlled study evaluated the effects of a six-month supervised resistance and weight-bearing exercise program on forearm muscle strength and radial bone health in institutionalized older adults.
- Conditions
- Forearm Muscle Strength, Radial Bone Health, Institutionalized Older Adults Keywords / MeSH
- Trial name
- SRWBE (NCT07831031)
- Testing
- Forearm-Focused Resistance and Upper-Extremity Weight-Bearing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Lifestyle, Healthy, Muscle Weakness
RE-inventing Strategies for Healthy Ageing; Recommendations and Tools
The goal of the RESTART RCT is to examine whether a complex lifestyle intervention, coordinated with municipal and non-government organizations (NGO), can establish and preserve improvements in risk factors and functional…
- Conditions
- Lifestyle, Healthy, Muscle Weakness, Abdominal Obesity, Cardiometabolic Syndrome
- Trial name
- RESTART (NCT06122441)
- Testing
- Complex lifestyle intervention, Physical activity monitoring and recommendations
- Where
- Norway
- Volunteers
- 119 people
- Sponsor
- University of Tromso
Chronic Pain, Musculoskeletal Pain
The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System
The goal of this study is to improve pain care in the MHS by identifying effective, whole-person, non-pharmacologic interventions for persons with chronic musculoskeletal pain.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Musculoskeletal Pain Disorder
- Trial name
- PROs (NCT06940986)
- Testing
- Empowered Relief, Move to Health, Usual Care as determined by primary care provider
- Where
- 5 sites in United States
- Volunteers
- 608 people
- Sponsor
- Brooke Army Medical Center
Bodily Distress Syndrome, Irritable Bowel
Health Care Use and Costs of Functional Somatic Disorders
The goal of this observational case-control study is to learn about direct healthcare use and costs of functional somatic disorders.
- Conditions
- Bodily Distress Syndrome, Irritable Bowel, Fibromyalgia, Chronic Widespread Pain
- Trial name
- NCT05811663
- Where
- Denmark
- Volunteers
- 9,656 people
- Sponsor
- Aarhus University Hospital
Menopause, Cardiovascular Health
Acute Physiological Effects of Greek Traditional Dancing
In Greece, people of different age groups, including young children to older adults, are involved in traditional dance. To date, the well-know benefits of dancing include entertainment, socialization and increased physical…
- Conditions
- Menopause, Cardiovascular Health, Body Composition, Physical Performance
- Trial name
- NCT06260124
- Testing
- Slow tempo, Moderate tempo, Fast tempo
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Muscle Weakness, Low Muscle Mass
Muscle Aging Phenotypes in Childhood Cancer Survivors
Childhood cancer survivors experience premature declines in muscle mass, strength, and physical function that contribute to morbidity and early mortality.
- Conditions
- Muscle Weakness, Low Muscle Mass, Sarcopenia
- Trial name
- NCT07531498
- Testing
- Multimodal Muscle Imaging and Functional Assessment, Multimodal Muscle Imaging and Neuromuscular Assessment, Comprehensive Muscle Phenotyping
- Where
- United States
- Volunteers
- 533 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Down Syndrome (DS), Supplementation
Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome
Purpose: This study will test whether 8 weeks of creatine and HMB supplementation can improve muscle strength, body composition, balance, and overall health in people with Down syndrome.
- Trial name
- NCT07213063
- Testing
- Nutrition education, Supplement
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Universidad de Burgos
Healthy, Perimenopausal Depression
Multidimensional Determinants of Functional Health In Women Aged 45-60
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years.
- Conditions
- Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density
- Trial name
- NCT07667699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital
Pre-Frailty, Sarcopenia
TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status
The purpose of this study is to compare the effects of a standardized Traditional Chinese Medicine (TCM) formula versus beta-hydroxy-beta-methylbutyrate (HMB) on muscle strength and bone health in pre-frail older adults .
- Conditions
- Pre-Frailty, Sarcopenia, Muscle Atrophy or Weakness, Osteoporosis
- Trial name
- TCM-HMB-PF (NCT07597850)
- Testing
- TCM Formula, HMB (beta-Hydroxy-beta-methylbutyrate)
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Old Age; Cachexia, Dietary Habits
The Nutritionist's Educational Intervention on the Protein Intake in Hospitalized Elderly People
The food intake is often compromised in the elderly, and during hospitalization, dietary restrictions may be imposed, making them more susceptible to the risk of malnutrition and sarcopenia.
- Conditions
- Old Age; Cachexia, Dietary Habits, Sarcopenia, Protein Malnutrition
- Trial name
- NCT05502445
- Testing
- educational intervention
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital Israelita Albert Einstein
Resilience, Cognitive Function and Well-Being
Aging Resilience Through Microbiota Optimization and Regulation
Sarcopenia, characterized by the progressive loss of muscle mass and strength in older adults, is a key factor in health deterioration.
- Conditions
- Resilience, Cognitive Function and Well-Being, Muscle Function, Handgrip Strength Test, Insulin Sensitivity
- Trial name
- ARMOR (NCT06649981)
- Testing
- FMT capsule
- Where
- 2 sites in Chile
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gonzalo Jorquera, PhD
Exercise Training
Football 4 Health in Middle-aged to Older Adults
Ageing in humans is accompanied by a progressive decline in lower-limb muscle power production. In addition to a decline in musculoskeletal fitness, ageing is associated with a reduction in cardiovascular and metabolic fitness.
- Trial name
- NCT05722899
- Testing
- Football training
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Sarcopenia, Frailty
Health Data from Well on My Legs Program
The percentage of people aged over 80 will double in 25 years, reaching 10% of the population. This means that care practices for older adults will have to be adapted.
- Conditions
- Sarcopenia, Frailty, Physical Inactivity, Fear
- Trial name
- DS-BSSJ (NCT06659484)
- Testing
- Assessment, Multicomponent exercise program, Follow-up at T3 + 6 months and T3 + 12 months
- Where
- France
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Depression, Anxiety
Progressive Muscle Relaxation in Nursing Students: Effects on Psychological and Biopsychosocial Outcomes
This randomised controlled trial aims to investigate the effects of progressive muscle relaxation exercises (PMRE) on depression, anxiety, stress, future-oriented attitudes, and biopsychosocial responses in nursing students.
- Conditions
- Depression, Anxiety, Stress, Psychological, Mental Health
- Trial name
- PRMNURSE (NCT07038109)
- Testing
- Progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Lupus, Dermatomyositis, Juvenile
Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress
The objectives of this study are to determine if the 'Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress' (TEAM-LEADS) intervention is feasible and acceptable to adolescents…
- Conditions
- Lupus, Dermatomyositis, Juvenile, Dermatomyositis, Lupus Erythematosus
- Trial name
- TEAM-LEADS (NCT06999109)
- Testing
- TEAM-LEADS
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University