Clinical trials: Muscle Damage
Femoral Neck Fractures, Pertrochanteric Fracture
Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures
The aim of this clinical trial is to compare serum concentration of bone intake proteins [ sex hormone-binding globulin (SHBG), cross linked C-telopeptide of type I collagen (CTX-I)] and muscle atrophy marker [creatine kinase…
- Conditions
- Femoral Neck Fractures, Pertrochanteric Fracture, Bone Resorption, Bone Loss
- Trial name
- NCT05804604
- Testing
- Surgical treatment of proximal femur fracture and blood sample test, Blood sample test
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Cerebral Palsy
Intensive Home-based Bimanual and Lower-limb Training in Young Children With Hemiplegia
A randomized control trial to test the efficacy of a new treatment involving intensive home-based bimanual training (Hand-Arm Bimanual Intensive Therapy (HABIT) and intensive home-based functional lower-limb training in children…
- Trial name
- NCT02299284
- Testing
- Intensive Home-based Bimanual and Lower-limb Training in Young Children With Hemiplegia
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Teachers College, Columbia University
Pain, Cerebral Palsy, Spastic
Botulinum Toxin-A as a Treatment for Chronic Muscle-Related Pain in Adults With Spastic Cerebral Palsy: a Randomized Controlled Trial
The purpose of this double-blinded, placebo-controlled study is to test if treatment with Botulinum toxin-A is effective in reducing chronic muscle-related pain in adults with spastic cerebral palsy.
- Trial name
- BATCP (NCT02434549)
- Testing
- Dysport®, Normal saline
- Where
- 2 sites in Sweden
- Volunteers
- 16 people
- Sponsor
- Kristina Tedroff
Cerebral Palsy
Muscle Activity With the Use of Ankle Foot Orthoses in Cerebral Palsy
The purpose of this study is to investigate the change in muscle activity during gait with the use of ankle foot orthoses in children diagnosed with hemiplegic cerebral palsy.
- Trial name
- NCT00462085
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Juçara Supplementatios After Muscle Damage
Juçara (Euterpe Edulis Martius) Supplementation Effect in Muscle Protection, Performance and Soreness in Lower Limbs After Exercise-Induced Muscle Damage
The purpose of this study is to find out if taking a natural supplement made from the Juçara fruit (a Brazilian berry rich in antioxidants called anthocyanins) can help the body recover faster after damage caused by exercise.
- Trial name
- NCT07584460
- Testing
- Juçara
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Santa Maria
Cerebral Palsy
Study Assessing High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations
To asssess efficacy of airway clearance provided by Vest therapy (HFCWO) in the reduction of respiratory exacerbations requiring hospitalization or antibiotic utilization in patients with muscle weakness and restrictive lung…
- Trial name
- NCT00739310
- Testing
- Vest Treatment (high frequency chest wall oscillation)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Hill-Rom
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Cerebral Palsy
Effects of Flywheel Exercise on Muscle and Walking Function in Teenagers and Young Adults With Cerebral Palsy
The main purpose of this project is to improve physical function and muscle health in teenagers and young adults with cerebral palsy (CP) by using an eccentric-overload resistance exercise model Specific aims 1.
- Trial name
- CP-Flywheel (NCT03124628)
- Testing
- Flywheel resistance exercise, Weight-stack resistance exercise
- Where
- Sweden
- Sponsor
- Karolinska Institutet
Cognitive Impairment
Impact of Resistance Training Volume on Cognitive Function and Physical Performance in Cognitively Impaired Individuals
This research project aims to analyze the effects of different resistance training volumes on cognitive function, oxidative stress, inflammatory markers, lipid profile, glycemic status, muscle damage, hemodynamic response, and…
- Trial name
- TRAIN4BRAIN (NCT06528951)
- Testing
- Control Phase ( 6Weeks), 15% increase in resistance training volume (10 Weeks), 30% increase in resistance training volume (10 Weeks)
- Where
- Portugal
- Volunteers
- 69 people
- Sponsor
- University of Beira Interior
Muscle Damage, Oxidative Stress
Iron Supplementation and Eccentric Exercise
Iron supplementation is very common in athletes, probably due to its catalytic role on the oxygen transport and optimal function of oxidative enzymes and proteins during exercise.
- Trial name
- NCT02374619
- Testing
- Iron supplement Resoferon Ferrous Sulfate
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Exercise Induced Muscle Damage
Muscle Health and Recovery in Older Adults
This is a prospective, randomized, placebo controlled, double-blinded study to evaluate the efficacy of a combination of nutritional ingredients on muscle health and recovery from a short bout of exhaustive exercise in healthy…
- Trial name
- NCT06205537
- Testing
- Control Liquid Supplement, Experimental Liquid Supplement
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Cerebral Palsy
Kinesio Taping in Sit to Stand Movement fo Cerebral Palsy
Children with Cerebral Palsy (CP) present limited performance of functional activities and activities of daily life. Kinesio taping has been definied as a promising technique for children with CP ans has been extensively used in…
- Trial name
- NCT03403322
- Testing
- Kinesio taping, Without taping
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Universidade Federal de Santa Catarina
Laser, Muscle; Fatigue, Heart
Photobiomodulation, Cryotherapy Combined With Compression, and Massage for Recovery
Skeletal muscle fatigue is an inevitable phenomenon in the training and competition routine for many crossfit athletes, which can impair their physical performance and predispose them to musculoskeletal injuries.
- Conditions
- Laser, Muscle; Fatigue, Heart, Muscle Damage
- Trial name
- NCT05627141
- Testing
- Photobiomodulation; Cryotherapy, Massage
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Anhanguera
Young Athletes
Effects of Manual Lymphatic Drainage and Pressotherapy on Muscle Recovery After Eccentric Exercise in Physically Active Young Adults
This randomized controlled trial aims to compare the effects of manual lymphatic drainage (MLD), intermittent pneumatic compression (IPC), and passive rest on recovery following exercise-induced muscle damage (EIMD) induced by a…
- Trial name
- LYMPH-REC (NCT07892105)
- Testing
- Manual Lymphatic Drainage, Intermittent Pheumatic Compression
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Camilo Jose Cela University
Spasticity, Stroke
Efficacy and Cost-effectiveness of Spasticity Treatment With Multifocal TENS
Spasticity is a common consequence of injury to the central nervous system and can be a major problem in motor function and everyday activities.
- Conditions
- Spasticity, Stroke, Cerebral Palsy
- Trial name
- NCT02261142
- Testing
- Multifocal TENS garment (Mollii®)
- Volunteers
- 31 people
- Sponsor
- Linkoeping University
Nutrition, Healthy, Muscle Damage
Early Time-Restricted Eating in Young Judo Athletes
This study investigates the effects of a 5-month early time-restricted eating (e-TRE) intervention on body composition, muscle damage biomarkers, and psychological variables in highly trained young male judo athletes.
- Conditions
- Nutrition, Healthy, Muscle Damage, Time Restricted Eating, Anxiety
- Trial name
- TRE-JUDO (NCT07671443)
- Testing
- Early Time-Restricted Eating (e-TRE)
- Where
- Tunisia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Manouba
Muscle Spasticity, Paralysis; Cerebral
The Decline in Walking Performance in Adults With Cerebral Palsy - Influence of Performance Fatigability
Due to an early brain injury occurring in antenatal or postnatal, cerebral palsy (CP) causes alteration in motor function with posture and gait disorders.
- Trial name
- FAT-GAIT (NCT06163950)
- Testing
- Fatigability assessment
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Peripheral Arterial Disease
Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis
Peripheral artery disease (PAD) is a manifestation of atherosclerosis that produces progressive narrowing and occlusion of the arteries supplying the lower extremities.
- Trial name
- NCT02842424
- Testing
- Ramipril
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Nebraska
Muscle Damage
Sex Differences in Muscle Damage Following Resistance Exercise With or Without Milk Protein Ingestion
Purpose: To investigate the impact of milk protein ingestion on resistance exercise-induced muscle damage in untrained males and females.
- Trial name
- EIMD-MILK (NCT04986150)
- Testing
- Resistance exercise
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durham University