Clinical trials: Multiplex PCR
Respiratory Syncytial Virus Infections, Immunocompromised Host
RSV, Influenza, and SARS-CoV-2 Outcomes in Severely Immunosuppressed Adults
Respiratory syncytial virus (RSV), influenza, and SARS-CoV-2 are common respiratory viruses. In healthy adults they usually cause mild, cold-like illness, but in people whose immune system is severely weakened - such as people…
- Conditions
- Respiratory Syncytial Virus Infections, Immunocompromised Host, Influenza, COVID - 19
- Trial name
- NCT07816471
- Volunteers
- 350 people
- Sponsor
- Hospital Italiano de Buenos Aires
Neuroblastoma
A Pilot Study on ALK Gene Mutations in Neuroblastoma
Neuroblastoma (NB) originates from the sympathetic nervous system and is one of the most common cancers in infants and children.
- Trial name
- NCT01986595
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Community-acquired Pneumonia
Role of Multiplex PCR in CAP
1. role of multiplex PCR in early identifying bacteria in patients with lower respiratory tract infection. 2. effect of early starting targeted antibiotics on outcome
- Trial name
- NCT06097117
- Testing
- MultiplexPCR
- Volunteers
- 66 people
- Sponsor
- Assiut University
Diarrhea Bloody
Improvements Through the Use of a Rapid Multiplex PCR Enteric Pathogen Detection Kit in Children With Hematochezia
Children presenting for emergency department (ED) care with bloody diarrhea (i.e. hematochezia) represent a diagnostic challenge.
- Trial name
- NCT03362970
- Testing
- BioFire Gastrointestinal Panel FilmArray®, Standard of Care
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Ventilator Associated Pneumonia ( VAP)
Combined Use of a Respiratory Multiplex PCR and Algorithm-based Therapy to Improve Early Optimization of Antibiotic Therapy in Critically Ill Patients With Ventilator-associated Pneumonia
Assess the impact of a strategy combining respiratory mPCR and algorithm-based therapy developed using local epidemiology on the early optimization of initial antibiotic therapy for ventilator-associated pneumonia (VAP)…
- Trial name
- SMART-VAP (NCT07403474)
- Testing
- strategy combining respiratory mPCR and algorithm-based therapy developed using local epidemiology
- Where
- 2 sites in France
- Volunteers
- 124 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Community-acquired Pneumonia, Critical Illness
Point-of-Care Multiplex for Adult Patients With Severe Community-acquired Pneumonia
Clinical Impact on Point-of-Care Multiplex PCR Testing for Critically Ill Adult Patients With Community-acquired Pneumonia - A cluster randomization study in ICU units within one medical center.
- Trial name
- NCT04835818
- Testing
- Provide the panel report to the primary care physician
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Lung Transplantation
Film Array Pneumonia Plus Panel® Multiplex PCR for Early Adaptation of Antibiotic Prophylaxis During Lung Transplantation
Postoperative pneumonia significantly worsens the prognosis for patients undergoing lung transplantation (LT). It is therefore recommended to use antibiotic prophylaxis after LT, although the specific types of antibiotics or the…
- Trial name
- FilmArray-TP (NCT07792018)
- Testing
- Early adapation of antibiotic prophylaxis according to FAPP results.
- Volunteers
- 98 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Genital Ulcer Disease (GUD)
New Multiplex Real-time PCR for Genital Ulcer Disease
(i) To compare a new diagnostic PCR with established diagnostic procedures for T. pallidum (serology, dark field microscopy), H. ducreyi (cultivation), HSV types 1 and 2 (cultivation, PCR).
- Trial name
- NCT01688258
- Testing
- Diagnostic swab
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- University of Zurich
Diabetes Mellitus, Foot Osteomyelitis
Assessment of PCR Multiplex Tests as a Tool to Obtain a Quicker Diagnosis of Bacteria Responsible for Foot Osteomyelitis Than Usual Cultures
Bone samples from infected diabetic feet will be collected and tests will be performed for the diagnosis of causative bacteria. Samples will be processed by PCR multiplex tests and usual cultures for identification of causative…
- Trial name
- RAPDIAGOS (NCT03434288)
- Testing
- Bone sampling
- Where
- France
- Volunteers
- 48 people
- Sponsor
- University Hospital, Montpellier