Clinical trials: Multimorbidity
Fragility, Multimorbidity
Effectiveness of Integrated Care Network
This project aims to examine the effectiveness of the community-based integrated care service model , based on a multi-domain intervention program, among community-dwelling older adults.
- Trial name
- NCT03528005
- Testing
- Multi-domain intervention
- Where
- 6 sites in Taiwan
- Volunteers
- 398 people
- Sponsor
- National Yang Ming Chiao Tung University
Type 2 Diabetes Mellitus, Cardiometabolic Conditions
Mi Puente: My Bridge to Better Cardiometabolic Health and Well-Being
Mi Puente (or "My Bridge") is a culturally-tailored, interdisciplinary approach designed to support at-risk Hispanic patients and their caregivers pre- and post-hospital discharge as they navigate the multi-level barriers that…
- Conditions
- Type 2 Diabetes Mellitus, Cardiometabolic Conditions, Behavioral Health Concerns
- Trial name
- Mi Puente (NCT02723019)
- Testing
- Volunteer Peer Mentor+Behavioral Health Nurse
- Where
- United States
- Volunteers
- 536 people
- Sponsor
- Scripps Whittier Diabetes Institute
Knee Osteoarthritis, Multimorbidity
Preoperative Multimorbidity and Functional Recovery After Total Knee Arthroplasty
This prospective observational cohort study aims to investigate the association between preoperative multimorbidity burden and functional recovery after primary total knee arthroplasty (TKA) in patients with knee osteoarthritis.
- Trial name
- NCT07882316
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Balikesir Ataturk City Hospital
Chronic Disease
Potentially Inappropriate Prescription Associated to Multimorbidity
A prospective multicenter cohort study in 5 hospitals in Spain will be initiated in 2016. Objectives: 1. To estimate and describe patterns of multimorbidity and polypharmacy in patients over 64 admitted for a chronic disease…
- Trial name
- PIMyC (NCT02830425)
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 740 people
- Sponsor
- Corporacion Parc Tauli
Statin Treatment for Primary Prevention
STREAM Trial - Statins in Multimorbid Older Adults Without Cardiovascular Disease
Statins are among the most widely used drugs. While they were found to be effective for primary and secondary prevention of cardiovascular disease (CVD) in middle-aged subjects, their benefits for primary prevention in older…
- Trial name
- STREAM (NCT05178420)
- Testing
- Statin discontinuation
- Where
- 24 sites in France, Netherlands and 1 more
- Volunteers
- 1,880 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Back Pain, Neck Pain
Exploring Multimorbidity in Patients With Spinal Pain
Spinal pain is frequently accompanied by other chronic conditions (multimorbidity) and the predicted rise in multimorbidity prevalence emphasizes the need for studies to understand its impact on patients with chronic pain…
- Conditions
- Back Pain, Neck Pain, Comorbidities and Coexisting Conditions
- Trial name
- NCT06402409
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Jacob Christiansen Gandløse
Multimorbidity
Trajectories and Experiences of People With Multimorbidity in Spain (LOXO-MULTIPAP) Project: a Mixed Methods Study
The overall objective of the study is to analyze the evolution of multimorbidity, its most relevant patterns and trajectories in the Spanish National Health System population, from 2012 to 2022, and to analyze the factors that…
- Trial name
- LOXO (NCT06478745)
- Testing
- Retrospective and prospective cohort, Focus group, semi-structured interviews and Photovoice, Systematic review
- Where
- Spain
- Volunteers
- 3,239,950 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Chronic Condition, Chronic Conditions, Multiple
EMBOSS A Person-centred Integrated-care for Chronic Diseases in Patients of Low Socio Economic Status
People of low socio economic status (SES) more often than others suffer from chronic diseases like diabetes mellitus, chronic obstructive pulmonary disease (COPD), or coronary diseases.
- Trial name
- EMBOSS (NCT05972031)
- Testing
- Person-centred integrated care intervention
- Where
- Netherlands
- Volunteers
- 540 people
- Sponsor
- Radboud University Medical Center
Multimorbidity
A New Organisation of Clinic for Multimorbidity and Polypharmacy
The purpose of this study is to investigate: 1) the implementation and 2) the effects of an outpatient program for patients with complex multimorbidity.
- Trial name
- NCT06735339
- Testing
- Clinic for Multimorbidity
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Central Jutland Regional Hospital
Obesity Morbid, Multimorbidity
Semaglutide and Physical Activity for Obesity and Multimorbidity
The aim of this observational study is to explore and describe changes in cardiometabolic health, physical activity, physical capacity, and wellbeing during interdisciplinary Semaglutide-based weight loss treatment in patients…
- Conditions
- Obesity Morbid, Multimorbidity, Obesity
- Trial name
- NCT06234111
- Testing
- Semaglutide 2.4 mg, total diet replacement, behavioural intervention
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Hvidovre University Hospital
Chronic Non-communicable Diseases, Cardiovascular Diseases
RegiStry Of the multiFaceted medIcal cenTer
This study is a prospective medical registry (the SOFIT Registry) that enrolls all patients hospitalized in various departments of the Tula Regional Clinical Hospital in 2021.
- Conditions
- Chronic Non-communicable Diseases, Cardiovascular Diseases, COVID-19, Multimorbidity
- Trial name
- SOFIT (NCT06803862)
- Where
- 2 sites in Russia
- Volunteers
- 21,783 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Multimorbid and Poly-treated Older People
A Protected Discharge Model Using Technology in Multimorbid and Poly-treated Older Subjects
The main goal of thi clinical trial is to evaluate if a protected discharge model can reduce the length of hospital stay in older participants aged over 65 years old who have been admitted to the hospital for an acute event and…
- Trial name
- PRO-HOME (NCT06227923)
- Testing
- PRO-HOME intervention
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Alberto Pilotto
Homelessness, Health Promotion
Pilot Feasibility Trial of HEALthy Beginnings for Middle-Aged, and Older Homeless Women
This is a mixed methods pilot feasibility trial of HEALthy Beginnings, an innovative, nurse-driven intervention. Middle-aged and older, homeless women (MAO-HW) will participate in the HEALthy Beginnings intervention and select…
- Conditions
- Homelessness, Health Promotion, Chronic Disease Self-care, Multimorbidity
- Trial name
- HB (NCT06743685)
- Testing
- HEALthy Beginnings
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of California, Los Angeles
Older Adults (60 - 85 Years Old), Self-care
Acceptance-based Self-care Intervention for Older Adults With Multimorbidity
The proposed 27-month three-arm parallel, repeated measure, randomized controlled trial aims to evaluate an acceptance-based self-care intervention for community-dwelling older adults with multimorbidity.
- Conditions
- Older Adults (60 - 85 Years Old), Self-care, Multimorbidity
- Trial name
- NCT07882992
- Testing
- Acceptance-based activities, Self-care activities
- Where
- Hong Kong
- Volunteers
- 306 people
- Sponsor
- Chinese University of Hong Kong
Polypharmacy Because of Multimorbidity in Geriatric Nursing Home Residents
Discontinuing Inappropriate Medication in Nursing Home Residents
Nursing home residents are among the frailest patient groups with a high number of co-morbidities and a high use of medicines. Inappropriate polypharmacy (i.e.
- Trial name
- NCT01876095
- Testing
- Multidisciplinary medication review
- Where
- Netherlands
- Volunteers
- 992 people
- Sponsor
- University of Groningen
Multimorbidity
Enhanced Care for Patients With Complex Multimorbidity in Primary Care
Introduction Patients living with a chronic disease often have more than one chronic condition, which is referred to as multimorbidity.
- Trial name
- MM600-DK (NCT05676541)
- Testing
- Complex intervention to enhance care for patients with multimorbidity in general practice consisting of an extended overview consultation and supporting elements
- Where
- Denmark
- Volunteers
- 117,000 people
- Sponsor
- University of Copenhagen
Advance Care Planning, Multimorbidity
ACP in Older Patients With Multimorbidity: a Randomized Pilot
Rationale A recent study into the patient perspective of patients with multiple chronic conditions in the Netherlands underlines the strain multimorbidity can put on people.
- Conditions
- Advance Care Planning, Multimorbidity, Old Age; Debility, Health Economics
- Trial name
- NCT04856202
- Testing
- Advance Care Planning interview
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Erasmus Medical Center
Multimorbidity, Geriatric Assessment
Compared Efficacy of Nurse-led and GP-led Geriatric Assessment in PrImary Care
Older patients account for around 10% of the population, of which 57% have a long-term illness, and 33% were admitted in the past year.
- Trial name
- CEPIA (NCT02664454)
- Testing
- health care organization
- Where
- France
- Volunteers
- 750 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertension, Diabetes
Exercise Impact in Elderly With Multimorbidity: HbA1c and Blood Pressure
The main objective of the study is to compare the effect of two different types of physical exercise modalities on glycated hemoglobin and blood pressure in elderly individuals with multimorbidity.
- Conditions
- Hypertension, Diabetes, Osteoarthritis, Depression Disorders
- Trial name
- NCT06879639
- Testing
- Exercise, Control
- Where
- Portugal
- Volunteers
- 63 people
- Sponsor
- Universidade do Porto
Cardiometabolic Diseases
Nutrition Counselling for Cardiometabolic Multimorbidity
Background: Cardiometabolic multimorbidity is rising globally and in Ethiopia, yet many patients still receive little or no structured dietary education in chronic care settings.
- Trial name
- NCT07712900
- Testing
- COM-B Model-Based Nutrition Counselling
- Where
- Ethiopia
- Volunteers
- 308 people
- Sponsor
- Bahir Dar University