Clinical trials: Multimorbidity
Multimorbidity, Knee Arthrosis
Interprofessional Preoperative Geriatric Assessment for Older Arthroplasty Patients With Multimorbidity
The objective of this randomized control trial is to investigate effects and cost effectiveness of interprofessional preoperative assessment among older knee or hip arthroplasty patients.
- Conditions
- Multimorbidity, Knee Arthrosis, Hip Arthrosis
- Trial name
- IPPGA-RCT (NCT04001699)
- Testing
- Preoperative geriatric assessment
- Where
- Finland
- Volunteers
- 157 people
- Sponsor
- University of Eastern Finland
Osteoarthritis, Knee, Osteoarthritis, Hip
Personalized Exercise Therapy and Self-management Support for Patients With Multimorbidity
Chronic conditions such as knee or hip osteoarthritis (OA), chronic obstructive pulmonary disease (COPD), heart failure (HF), coronary heart disease (CHD), hypertension, type 2 diabetes mellitus (T2DM) and depression are among…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Heart Failure, Coronary Heart Disease
- Trial name
- MOBILIZE (NCT04645732)
- Testing
- Personalized exercise therapy and self-management support program, Usual care
- Where
- 16 sites in Denmark
- Volunteers
- 228 people
- Sponsor
- University of Southern Denmark
Multimorbidity, Polypharmacy
Multi-PAP: Improving Prescription in Primary Care Patients With Multimorbidity and Polypharmacy
This study assesses the effectiveness of a complex intervention in young-old patients with multimorbidity and polypharmacy aimed at improving physician drug prescription in primary care, measured by means of the Medication…
- Conditions
- Multimorbidity, Polypharmacy, Other Diagnoses, Comorbidities, and Complications
- Trial name
- Multi-PAP (NCT02866799)
- Testing
- Multi-PAP, Usual care
- Where
- 3 sites in Spain
- Volunteers
- 593 people
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Major Depressive Disorder (MDD), Breast Cancer Survivor
Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in Pakistan
Breast cancer is the most common cancer among women worldwide, and many survivors experience comorbid mental health conditions such as depression and anxiety, which can significantly worsen health outcomes and increase mortality.
- Trial name
- Moving On ABC (NCT07015944)
- Testing
- Non-specialist delivered Low intensity guided self-help (Khushi and Khatoon), Moving on After Breast Cancer (ABC) plus, Standardised pharmacological treatment (antidepressants)
- Where
- Pakistan
- Volunteers
- 26,376 people
- Sponsor
- Pakistan Institute of Living and Learning
Multimorbidity, Heart Failure
Effectiveness of a Multimodal Intervention With Simulation for Learning Home Health Nursing Care of Patients With Multimorbidity and Heart Failure
The goal of this clinical trial is to evaluate the efficacy of a multimodal intervention with high-fidelity simulations on home health nursing in improving the care of multipathological patients with heart failure in nursing…
- Trial name
- NCT06855719
- Testing
- Training in high-fidelity simulation and knowledge of care protocols in patients with multimorbidity and heart failure
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Older Adults (60 - 85 Years Old), Self-care
Acceptance-based Self-care Intervention for Older Adults With Multimorbidity
The proposed 27-month three-arm parallel, repeated measure, randomized controlled trial aims to evaluate an acceptance-based self-care intervention for community-dwelling older adults with multimorbidity.
- Conditions
- Older Adults (60 - 85 Years Old), Self-care, Multimorbidity
- Trial name
- NCT07882992
- Testing
- Acceptance-based activities, Self-care activities
- Where
- Hong Kong
- Volunteers
- 306 people
- Sponsor
- Chinese University of Hong Kong
Chronic Condition, Chronic Conditions, Multiple
OPTIMA FORMA Phase 3
Chronic diseases and multimorbidity are increasingly prevalent. However, over the last decades, attempts at improving primary care for chronic diseases have been focussed on the management of individual chronic diseases and…
- Trial name
- OPTIMAFORMA3 (NCT05495230)
- Testing
- Person-centred integrated care intervention, Usual care
- Where
- Netherlands
- Volunteers
- 842 people
- Sponsor
- Radboud University Medical Center
Multimorbidity, Health Knowledge, Attitudes, Practice
Clinical Complexity in Internal Medicine Wards. San MAtteo Complexity Study
The progressive rising of multimorbidity, which has been always considered the hallmark of clinical complexity (CC), has made management of the "complex" patient one of the most topical and challenging issues in medicine.
- Trial name
- SMAC (NCT03439410)
- Testing
- Clinical Complexity Index
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Stroke, Traumatic Brain Injury
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention
The aging population and its accompanying burden from non-communicable chronic diseases predicts an increasing impact imposed by frailty on healthcare systems.
- Conditions
- Stroke, Traumatic Brain Injury, Knee Osteoarthritis, Breast Cancer
- Trial name
- OPTIMA-C (NCT06073106)
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Tan Tock Seng Hospital
Chronic Disease
Multimorbidity Management Supported by a Digital Platform
This study aims to assess whether the use of the METHIS digital platform using a patient-centered approach contributes to an improvement in the quality of life, mental health and physical activity of patients with multimorbidity…
- Trial name
- NCT05593835
- Testing
- METHIS Platform, Goal-Oriented Care Training Program
- Volunteers
- 1,380 people
- Sponsor
- Universidade Nova de Lisboa
Multimorbidity, Comorbidity
A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in the Prevention of Comorbidity Among Junior Middle School Students
Junior high school students are in a critical period of physical and mental development, currently facing two major health challenges: first, persistently high rates of myopia with a noticeable trend toward younger onset; second…
- Conditions
- Multimorbidity, Comorbidity, Common Diseases in Children and Adolescents, Myopia
- Trial name
- NCT07237698
- Testing
- The intervention group participated in specialized physical education courses.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Xiaoyan Wu
Chronic Disease
Nursing Discharge Teaching for Multimorbid Inpatients
The objective of this study is to estimate the effect size of a nursing discharge teaching intervention on multimorbid inpatients activation level, health confidence, readiness for hospital discharge, experience with discharge…
- Trial name
- NCT04253665
- Testing
- Nursing discharge teaching
- Where
- 3 sites in Switzerland
- Volunteers
- 225 people
- Sponsor
- University of Lausanne
Elderly, Polypharmacy
Elderly Appropriate Treatment in Primary Care (EAT)
The general practitioner (GP) is confronted, for a part of his clientele, with the management of patients suffering from multimorbidity, leading most often to a polypharmacy.
- Trial name
- TAPAGE (NCT03298386)
- Testing
- Systematic medication review with the STOPP/START tool
- Where
- France
- Volunteers
- 3,032 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Elderly Care, Length of Hospital Stay
Emergency Room Evaluation and Recommendations for Older Users of Emergency Departments
The study evaluates if the Emergency Room Evaluation and Recommendation Tool (ER2) reduces the hospital admission rate and the length of stay in Emergency.
- Conditions
- Elderly Care, Length of Hospital Stay, Multimorbidity
- Trial name
- NCT04022551
- Where
- Canada
- Volunteers
- 4,724 people
- Sponsor
- Jewish General Hospital
Frailty, Disability
Multidisciplinary Mobile Unit for Preventing Hospitalization of Nursing Home Residents
Elderly patients residing in nursing homes are particularly at risk of experiencing urgent medical problems needing admission to the Emergency Department (ED).
- Conditions
- Frailty, Disability, Multimorbidity, Respiratory Failure
- Trial name
- MMU-1 (NCT04085679)
- Testing
- Multidisciplinary Mobile Unit (MMU)
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Chronic Conditions, Multiple, Aging
Physical Literacy and Rehabilitation
With the aging population, the prevalence of chronic conditions continues to rise, affecting 1/3 of Canadians. The promotion of physical literacy, defined as "the motivation, confidence, physical competence and knowledge, to take…
- Conditions
- Chronic Conditions, Multiple, Aging, Mobility Limitation
- Trial name
- NCT04494711
- Testing
- Physical Functional Literacy for Adults
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Julie Richardson
Multimorbidity
Improving Patient and Caregiver Engagement by Sharing Annotated Audio-recorded Clinic Visits
In this project, the investigators will conduct a three-arm patient-randomized pilot trial in older adults with multimorbidity in ambulatory care settings to determine the feasibility, usability, and acceptability of an…
- Trial name
- NCT04827381
- Testing
- Annotated Audio, Audio
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
End Stage Renal Disease
SPIRIT for Persons With Dementia and Complex Multimorbidity
In this study, 30 patient and caregiver dyads will be randomized to receive the SPIRIT-dementia intervention or usual care. Participants will be follow-up with 2-3 days after the intervention to evaluate the impact of SPIRIT on…
- Trial name
- NCT04108000
- Testing
- SPIRIT-Dementia, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 38 people
- Sponsor
- Emory University
Youth with Multimorbidity or Rare Dieases
Evaluation of the TAC Program
This is a mixed-methods evaluative study examining the effectiveness of the Transition to Adult Care Program at the Hospital for Sick Children (TAC) Program on high-risk youth with medical and psychosocial complexity…
- Trial name
- NCT06583525
- Testing
- Intensive Transition Support
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- The Hospital for Sick Children
Multiple Chronic Conditions
Self-Management Interventions Using Mobile Health for the Multimorbid
The purpose of this pilot study is to evaluate the feasibility and impact of delivering mobile health self-management interventions to improve adherence to the prescribed treatment in a multimorbid population returning home after…
- Trial name
- NCT04566107
- Testing
- mHealth intervention, mHealth Plus
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Nebraska