Clinical trials: Multimodal Intervention
Accidental Falls
Effect on Falls Reduction of a Multimodal Intervention in Frail and Pre-frail Elderly Community-dwelling People
Practice guidelines in caring for the geriatric population recommend performing an annual screening of falls . However, one of the problems that interfere with fall prevention programs is the lack of importance accorded to health…
- Trial name
- FAREMAVA (NCT02631330)
- Testing
- Multicomponent physical activity
- Where
- Spain
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Hospital de la Ribera
Ear Noise, Tinnitus, Noise Induced
Multimodal Therapy for Somatosensory Tinnitus
Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of the adult population and significantly reduces quality of life in many patients.
- Conditions
- Ear Noise, Tinnitus, Noise Induced, Tinnitus, Subjective, Headache Other
- Trial name
- SOMATIN (NCT07468318)
- Testing
- Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Obesity
Effects of a Multimodal Preference-based Parental Intervention on Preschoolers' Physical Activity Behaviour - a Cluster-randomized Trial
This study investigates whether a preschool-based physical activity intervention involving parents as active agents of behavioral change affects objectively measured physical activity in preschool children.
- Trial name
- NCT01070251
- Testing
- Participatory parent-focused intervention, State-sponsored PA program
- Where
- 2 sites in Germany
- Volunteers
- 826 people
- Sponsor
- Heidelberg University
Critical Illness, Post Intensive Care Syndrome (PICS)
Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)
This two-arm, parallel-group randomized clinical trial investigates the effectiveness of an additional telerehabilitation program compared with standard care in patients with Post-Intensive Care Syndrome (PICS).
- Conditions
- Critical Illness, Post Intensive Care Syndrome (PICS), Cardiopathy
- Trial name
- CARDIO-PICS (NCT07599306)
- Testing
- Tele-rehabilitation, Standard of Care
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Metastatic Breast Cancer, Cancer-Related Fatigue
Multimodal Exercise and Education Program in Metastatic Breast CancerMostrar más líneas
This longitudinal pre-post study evaluates the effects of a 12-week community-based multimodal intervention combining supervised physical exercise and health education in women with metastatic breast cancer receiving active…
- Conditions
- Metastatic Breast Cancer, Cancer-Related Fatigue, Quality of Life
- Trial name
- MBC_MME (NCT07693985)
- Testing
- Multimodal Oncology-Based Intervention for Metastatic Breast Cancer
- Where
- Spain
- Volunteers
- 37 people
- Sponsor
- University of Valencia
Bone Marrow Transplant Complications, Hematologic Malignancy
BMT-CARE: Psychosocial Intervention for Transplant Caregivers
The goal of this study is to evaluate whether a psychological intervention (BMT-CARE) is effective at improving the quality of life in caregivers and patients treated with hematopoietic cell transplant compared to usual care, and…
- Trial name
- BMT-CARE (NCT06472089)
- Testing
- BMT-CARE, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- Massachusetts General Hospital
Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.
The goal of this clinical trial is to learn whether a hybrid multidomain lifestyle program can prevent cognitive decline and reduce dementia risk in community-dwelling adults in mid- to late life who are at increased risk of…
- Trial name
- LETHE-AT (NCT07376135)
- Testing
- A tailored hybrid multidomain lifestyle intervention group, Self-guided multimodal lifestyle advice group
- Where
- 3 sites in Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Alzheimer Disease
Playful Multimodal Intervention, Monitoring and Decision Support for Activation of People With Alzheimer's Dementia
The worldwide prevalence of dementia is increasing. Pharmaceutical therapies, at the best, slow the degenerative process, observable in Alzheimer's disease (AD).
- Trial name
- M-AAL (NCT04628702)
- Testing
- tablet training
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Medical University of Graz
Mild Cognitive Impairment
Effects Multimodal Mind and Body Approach for MCI
The aim of this application is to develop a computer-based multimodal mind and body approach (CMMBA) for mild cognitive impairment (MCI).
- Trial name
- NCT06814483
- Testing
- Experimental: A computer-based multimodal mind and body approach (cbMMBA), A standard cognitive training group
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Massachusetts General Hospital
Multiple Sclerosis
Neurodynamic Interventions for Multiple Sclerosis
A randomized, parallel-group, clinical trial will be conducted to compare the immediate effects of the inclusion of a neurodynamic intervention into a multimodal physiotherapy program on pressure pain sensitivity, pain and manual…
- Trial name
- NCT03595631
- Testing
- Physical Therapy, Physical Therapy plus Neurodynamic
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Universidad Rey Juan Carlos
Endometrial Cancer
ImpRoving hEalth behaviourS for LIfe After ENdometrial CancEr Trial
RESILIENCE is 24-week randomized controlled trial that assesses the efficacy of a digital wellness platform, combined with online support from healthcare professionals, to enhance waist circumference and other vital health…
- Trial name
- RESILIENCE (NCT06038032)
- Testing
- Digital wellness platform, Online healthcare professional support
- Where
- 2 sites in Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Acute Leukemia
Patient Activation, Counseling and Exercise - Acute Leukemia (PACE-AL)
The purpose of this study is to test a new preventive and restorative intervention for patients with acute leukaemia undergoing consolidation chemotherapy, to measure and delineate the patients' treatment related symptom burden…
- Trial name
- PACE-AL (NCT01404520)
- Testing
- Exercise based multimodal intervention
- Where
- 2 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Universitetshospitalernes Center for Sygepleje
Antimicrobial Stewardship, Antibiotics Causing Adverse Effects in Therapeutic Use
A Multimodal Intervention to Optimise Antimicrobial Use in Residential Aged Care Facilities (ENGAGEMENT Study)
The antimicrobial stewardship ENGAGEMENT study aims to deliver a bundle of interventions, including education of GPs and nursing staff, guideline implementation and telehealth support for 18 residential aged care facilities…
- Trial name
- ENGAGEMENT (NCT04705259)
- Testing
- Antimicrobial Stewardship ENGAGEMENT bundle
- Where
- 4 sites in Australia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Developmental Dyslexia
Prediction and Intervention in Developmental Dyslexia
The long-term goal of this study is to improve prediction of poor reading outcome at preschool age by using a combination of behavioural and neuroimaging measures and to evaluate a specific computerized training program to…
- Trial name
- LEXI (NCT02217696)
- Testing
- Computerized reading training
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hypertension, Aging
ACE Inhibitors Combined With Exercise for Seniors - Pilot Study
The purpose of this study is to compare, when combined with chronic exercise, the effects of perindopril, losartan, and hydrochlorothiazide.
- Trial name
- ACES-P (NCT01891513)
- Testing
- Exercise, ACE inhibitor + exercise, Thiazide diuretic + exercise
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Florida
Prodromal Schizophrenia
"Multimodal Prevention of Psychosis - Investigating Efficacy of N-Acetylcysteine and Psychotherapy in CHR-Patients"
Schizophrenia is a severe mental disorder associated with significant impairments in affective, cognitive and social functioning.
- Trial name
- ESPRIT-B1 (NCT03149107)
- Testing
- N-Acetylcysteine, IPPI (Integrated Preventive Psychological Intervention), PSM (Psychological stress management)
- Where
- 10 sites in Germany
- Volunteers
- 48 people
- Sponsor
- University Hospital, Bonn
Anxiety Disorder of Adolescence
AI-Driven Multimodal Therapeutic System With Virtual Reality Integration for Anxiety Disorders in Adolescents
Many young people in the Middle East face anxiety problems, and social stigma often stops them from getting help. Doctors' usual talks sometimes miss the right diagnosis, and most treatments only target one part of anxiety…
- Trial name
- NCT07364136
- Testing
- Ísland app
- Where
- Egypt
- Volunteers
- 587 people
- Sponsor
- STEM Egypt
Cervical Cancer, Sexual Dysfunction
A Multimodal Intervention Program to Improve Sexual Health and Self-perceived Quality of Life in Patients Treated for Cervical Cancer (PROVIDENCE)
The PROVIDENCE Trial aims to explore the improvement of sexual health and self-perceived health related quality of life (measured by Patient Reported Outcome Measures) through a multimodal intervention that includes patient…
- Conditions
- Cervical Cancer, Sexual Dysfunction, Quality of Life
- Trial name
- PROVIDENCE (NCT06031493)
- Testing
- Multimodal intervention on sexual dysfunction and quality-of-life
- Where
- 2 sites in Spain
- Volunteers
- 122 people
- Sponsor
- Hospital Clinic of Barcelona
Angina, Acute Bronchiolitis
Impact of a Multimodal Intervention on Antibiotic Prescribing for Respiratory Infections in Primary Care
Antimicrobial resistance (AMR), considered one of the greatest global threats by the WHO, justifies the development of initiatives to promote appropriate antibiotic use-especially in primary care, where most antibiotics in France…
- Conditions
- Angina, Acute Bronchiolitis, Acute Bronchitis, COPD Exacerbation (AECOPD)
- Trial name
- GRASP (NCT07359287)
- Testing
- Antibiotic prescribing according to guidelines
- Where
- France
- Volunteers
- 4,500 people
- Sponsor
- University Hospital, Caen
Alcohol Use Disorder (AUD)
Multimodal Intervention for GGT Reduction in Alcohol Use Disorder (GGT-AUD)
The aim of this clinical trial is to evaluate whether a combined nutraceutical and psychological intervention can reduce gamma-glutamyl transferase (GGT) levels in individuals with Alcohol Use Disorder (AUD).
- Trial name
- GGT-AUD (NCT07603726)
- Testing
- Alcohol Reduction Counseling, Nutraceutical Treatment, Psychological Intervention
- Where
- Romania
- Volunteers
- 197 people
- Sponsor
- Medical Center TOPMED