Clinical trials: Multicenter Clinical Study
GDM
"Mantou" Screening for GDM Before 20 Weeks of Gestation
Gestational diabetes mellitus (GDM) can occur in overweight, hyperinsulinemia, insulin resistance pregnant women, or lean, insulin deficiency pregnant women.
- Trial name
- NCT06436794
- Where
- China
- Volunteers
- 5,925 people, healthy volunteers welcome
- Sponsor
- Jiang Ziyan
Postpartum Depression
Effect of Consuming a Combination of Probiotic Strains on Postpartum Depression
The objective of this trial is to evaluate the effect of consuming a combination of Lactobacillus during the pregnancy and lactation period on the incidence of postpartum depression.
- Trial name
- NCT06651424
- Testing
- Combination of Lactobacillus probiotics (no comercial)
- Where
- 3 sites in Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Incontinence-associated Dermatitis
Prevention of Incontinence-associated Dermatitis and Maintenance of Local Skin Microclimate：A Multicenter Study
To explore the feasibility of Jefcare Sterile Medical Sheets in preventing incontinence-associated dermatitis and maintaining a stable local skin microclimate in adult patients in the intensive care unit.
- Trial name
- I-and-M-m (NCT06644027)
- Testing
- Jefcare Sterile Medical Sheets, Molicare Premium Bed Mat
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Absenteeism, Sick Leave
WB6Dim-LTSA: Can Workplace Well-Being Scores Predict Collective Absenteeism?
This prospective multicenter cohort study evaluates the predictive value of the Adaptive Load Index (ICA), a composite indicator derived from the WB6Dim well-being instrument, on long-duration sick leave (≥ 30 days) in French…
- Conditions
- Absenteeism, Sick Leave, Workplace Well-Being, Occupational Stress
- Trial name
- WB6Dim-LTSA (NCT07606261)
- Where
- France
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Clover Link
Covid19
Safety and Immunogenicity Study of AdCLD-CoV19-1: A COVID-19 Preventive Vaccine in Healthy Volunteers
This is a Phase 1 clinical trial to assess the safety and immunogenicity of AdCLD-CoV19-1 in healthy adults.
- Trial name
- NCT05047692
- Testing
- AdCLD-CoV19-1
- Where
- 3 sites in South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cellid Co., Ltd.
Perioral Rhytids, Aging
RHA Redensity - Perioral Rhytids
Randomized, blinded, No-Treatment control, multi-center, prospective clinical study, to identify whether TEOSYAL RHA® Redensity is more effective than No-Treatment in the correction of moderate to severe dynamic perioral rhytids…
- Conditions
- Perioral Rhytids, Aging, Wrinkle
- Trial name
- NCT03092219
- Testing
- TEOSYAL RHA Redensity
- Where
- 8 sites in United States, Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Wrinkle, Rhytides
Renuvion Dermal System for Dermal Resurfacing
This is a multi-center, single arm, evaluator-blind prospective study of up to 55 study subjects who are seeking a procedure to reduce the appearance of wrinkles and rhytides.
- Trial name
- NCT04185909
- Testing
- Renuvion Dermal System
- Where
- 4 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Japanese Encephalitis
Immunogenicity of a Commercial Batch of JEV IC51 up to 24 Months Post Filling
The objective is to assess immunogenicity of a commercial IC51 batch at 3 different time points post filling (12, 18, 24 months) in terms of Geometric Mean Titers (GMT) for anti-JEV neutralizing antibodies at Day 56 after the…
- Trial name
- NCT00776230
- Testing
- IC51
- Where
- 3 sites in Austria, Germany
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Valneva Austria GmbH
Healthy, Systemic Sclerosis
Systemic Sclerosis Clinical and Biomarker Study
The primary objective of the study is to assess the change in systemic sclerosis (SSc)-associated gastrointestinal (GI) tract symptoms over a 1-year period in participants with SSc.
- Trial name
- NCT02531009
- Volunteers
- healthy volunteers welcome
- Sponsor
- Biogen
Hemophilia
Self-myofascial Release With Foam Roller in Patients With Hemophilic Ankle Arthropathy
Introduction: Hemophilic ankle arthropathy is manifested by degenerative functional alterations (deficit of muscle strength, mobility and proprioception) (intra-articular alterations) and chronic pain.
- Trial name
- NCT03914287
- Testing
- Self-Myofascial release
- Where
- Spain
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Breakthrough Bleeding
A Study to Evaluate Bleeding Patterns With Three Different Doses of DR-1031 Compared to Seasonale
This is a 4-arm study to evaluate and compare bleeding patterns between three different doses of DR-1031 oral contraceptive with Seasonale oral contraceptive.
- Trial name
- NCT00394771
- Testing
- DR-1031, Seasonale®, Portia®
- Where
- 50 sites in United States
- Volunteers
- 567 people, healthy volunteers welcome
- Sponsor
- Duramed Research
Pregnancy Complications, Hemorrhage
Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Caesarean Delivery
TRACES trial is a multicenter randomized double blind placebo control therapeutic and pharmaco-biological dose ranging study to measure the effect on blood loss reduction of a single intravenous infusion of two doses regimens…
- Trial name
- TRACES (NCT02797119)
- Testing
- tranexamic acid 1 g (TA1), tranexamic acid 0.5 g (TA1/2), Saline Solution (TA0)
- Where
- 5 sites in France
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Infection
The Microbiologic Profile of Diabetic Foot Infections in Turkey - TURK-DAY
To determine the causative microorganisms and their antibiotic sensitivity patterns in diabetic patients with a foot infection in Turkey.
- Trial name
- TURK-DAY (NCT02026830)
- Where
- Turkey (Türkiye)
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Moderate to Severe Midface Volume Deficit
Saypha® VOLUME Lidocaine for Midface Augmentation
The clinical investigation is a randomized, subject- and evaluator-blinded, active treatment controlled, multicenter, clinical investigation, to demonstrate the non inferiority of saypha® VOLUME Lidocaine to one of the devices…
- Trial name
- VOLIDO (NCT05386030)
- Testing
- saypha® VOLUME Lidocaine, Juvéderm® Voluma™ XC
- Where
- 16 sites in United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Hyperlipidemia
A Study Of Nutraceutical Drinks For Cholesterol (Evaluating Effectiveness and Tolerability)
Great controversy exists about the feasibility and safety of a product that can be employed for self-directed cholesterol reduction.
- Trial name
- NCT01152073
- Testing
- Second Formulation, Third Formulation
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Healthy Drink Discoveries, Inc.
Diphtheria, Tetanus
Post-authorization Safety Study of Euforvac-Hib Vaccine for Active Primary Immunization in Infants From 6 Weeks
A multicenter, observational study to evaluate the safety of Euforvac-Hib vaccine for active primary immunization against diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenza type B in infants.
- Conditions
- Diphtheria, Tetanus, Pertussis, Hepatitis B
- Trial name
- NCT02257645
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Coronavirus Disease (COVID-19)
Study of MK-4482 for Prevention of Coronavirus Disease 2019 (COVID-19) in Adults (MK-4482-013)
The purpose of the study is to assess if the study medication (molnupiravir, MK-4482) will prevent symptomatic coronavirus disease 2019 (COVID-19) in adults who live with someone with confirmed COVID-19 infection.
- Trial name
- MOVe-AHEAD (NCT04939428)
- Testing
- Molnupiravir
- Where
- 226 sites in United States, Argentina and 21 more
- Volunteers
- 2,441 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Acute Kidney Injury, Transient Acute Renal Failure
Impact of the Characteristics of Acute Renal Failure in Intensive Care on the Long-term Renal Prognosis: Prospective Multicenter Cohort Study
The purpose of this study is to assess the impact of Acute Kidney Injury (AKI) characteristics on long-term renal prognosis in Intensive Care Unit (ICU) patients.
- Conditions
- Acute Kidney Injury, Transient Acute Renal Failure, Persistent Acute Renal Failure
- Trial name
- MAKI (NCT05247502)
- Testing
- Data observation
- Where
- 2 sites in France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Partial Edentulism, Tooth Disease
TM vs TSV Implants Loaded Early vs Conventional in Anterior and Posterior Areas
Randomized-controlled, multicenter study of Trabecular Metal (TM) and Tapered Screw-Vent (TSV) dental implants loaded early in maxillary and mandibular sites.
- Trial name
- TMEL (NCT02158377)
- Testing
- Trabecular metal dental implants (TM), Tapered screw-vent implants (TSV)
- Where
- 3 sites in Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ZimVie
HIV-1-infection
REal-Life Cohort With DOlutegravir + LAmivudina
Since 1996, HAART based on 3-drug regimens (3DR) in people living with HIV (PLHIV) has decreased mortality and today, PLHIV have a life expectancy close to that of the general population.
- Trial name
- REDOLA (NCT04638686)
- Testing
- Dolutegravir 50 MG, Lamivudine 300 MG
- Where
- Spain
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
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