Clinical trials: Mucositis
Mucositis
Effect of Lactobacillus Brevis CD2 in Prevention of Radio-chemotherapy Induced Oral Mucositis in Head and Neck Cancer
Oral mucositis is a debilitating side effect for oncology patients and there is a clear need for new therapeutic options. The lozenges containing Lactobacillus brevis CD2 proved a potential new alternative for the prevention of…
- Trial name
- NCT01707641
- Testing
- CD#2, bicarbonate sodium mouthwash
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- S. Andrea Hospital
Mucositis, Recurrent Squamous Cell Carcinoma of the Hypopharynx
Entolimod in Treating Patients With Stage III-IV Squamous Cell Head and Neck Cancer Receiving Cisplatin and Radiation Therapy
This phase I trial studies the side effects and best dose of entolimod in treating patients with stage III-IV or recurrent head and neck cancer.
- Conditions
- Mucositis, Recurrent Squamous Cell Carcinoma of the Hypopharynx, Recurrent Squamous Cell Carcinoma of the Larynx, Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity
- Trial name
- NCT01728480
- Testing
- entolimod, intensity-modulated radiation therapy, cisplatin
- Sponsor
- Roswell Park Cancer Institute
Oral Mucositis
Efficacy of Propolis in the Prevention of Oral Mucositis
The study was carried out to determine the efficacy of propolis in the prevention of oral mucositis and gastrointestinal symptoms associated with oral mucositis in patients with leukemia, lymphoma, and myelodysplastic syndrome…
- Trial name
- OM (NCT05250661)
- Testing
- Aqueous propolis extract
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Karadeniz Technical University
Peri-Implantitis, Peri-implant Mucositis
Proteomic Analysis of Newly Restored Single Implants
In 10 systemically healthy non-smokers, free of periodontitis, one newly restored implant (baseline-T0) and one corresponding tooth were followed over 12 months (T1). All implants were screw-retained, and platform-switched.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Periodontal Diseases
- Trial name
- NCT06379022
- Testing
- Plaque control
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Autologous Stem Cell Transplant
High Heated Humidity in Stem Cell Transplant
The purpose of this study is to find out what effects of high heated humidity has on you and your mucositis.
- Trial name
- NCT05358262
- Testing
- Airvo, Standard of Care
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- AHS Cancer Control Alberta
Radiation Induced Oral Mucositis
Appaconitine Patch for Oral Mucositis Pain Caused by Chemoradiotherapy in Patients With Nasopharyngeal Cancer
The purpose of this clinical study is to evaluate the efficacy of lappaconitine adhesive patch in alleviation radiation induced mucositis pain and the improvements in QOL of patients with nasopharyngeal carcinoma .
- Trial name
- NCT03518489
- Testing
- Lappaconitine Adhesive Patch, standard care
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Fujian Cancer Hospital
Oral Mucositis Due to Chemotherapy
Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients
The goal of this clinical trial is to evaluate the efficacy of propolis in the prevention of oral mucositis and reducing pain score in children undergoing chemotherapy, and assessing its impact on body mass index, pediatric…
- Trial name
- NCT07073092
- Testing
- propolis, chlorohexidine mouthwash and topical antifungal
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Oral Ulcer Due to Pemphius Vularis, Oral Ulcer Due to Benign Mucous Membrane Pemphioid
PRF in Management of Chronic Multiple Oral Ulcers
PRF in orabase will be applied as a pack material on chronic oral ulcers of chronic multiple oral lesions compared to conventional topical steroid therapy with clobetasol propionate 0.05% in orabase.
- Conditions
- Oral Ulcer Due to Pemphius Vularis, Oral Ulcer Due to Benign Mucous Membrane Pemphioid, Oral Ulcer Due to Steven Johnson's Syndrome
- Trial name
- NCT03878771
- Testing
- Platelet rich fibrin gel in Orabase, Dermovate cream in Orabase
- Where
- Egypt
- Volunteers
- 804 people
- Sponsor
- Beni-Suef University
Peri-implant Mucositis, Peri-Implantitis
Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical
Bleeding on probing (0,1,2,3), plaque index (+,-) and pocket probing depth will be recorded for each visit. Before the procedure, the patient will be randomly assigned to one of four groups and records will be kept.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Bleeding on Probing, Periodontal Pocket
- Trial name
- NCT06287957
- Testing
- Labrida BioClean, EMS Handy 3.0 Perio Premium
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Oral Mucositis, Stomatitis
Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients
This study aims to see if a single intravenous infusion of a cell therapy called Amimestrocel injection can help prevent severe mouth sores (oral mucositis) in patients receiving a stem cell transplant.
- Conditions
- Oral Mucositis, Stomatitis, Gastrointestinal Mucositis, Hematopoietic Stem Cell Transplantation
- Trial name
- NCT07400328
- Testing
- Amimestrocel injection
- Where
- China
- Volunteers
- 22 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Mucositis
To Access the Effects of Mucositis in Adults With Dental Implants
Clinical research for the treatment of mucositis subjects who have dental implants for a minimum of one-year.
- Trial name
- implantitis (NCT01072201)
- Testing
- Triclosan and Fluoride, Fluoride
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Peri-Implantitis, Peri-implant Mucositis
Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study
Although smoking has been proposed as well, as a risk factor/indicator for peri-implantitis, there is currently no conclusive evidence. The current literature confronts the inconclusive evidence of tobacco for a risk factor.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Bone Loss, Alveolar
- Trial name
- NCT04952428
- Testing
- Re-examination visit ("today visit")
- Where
- Spain
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Oral Mucositis (Ulcerative) Due to Radiation
A Prospective Study on the Therapeutic Outcomes of Mebo and Tantum Verde in Patients With Oral Mucositis
This study aimed to assess the efficacy of MEBO® in the treatment of already established oral mucositis. This is a randomized controlled clinical trial.
- Trial name
- NCT07186114
- Testing
- MEBO Wound Ointment (MEBO), Tantum Verde® mouthwash
- Where
- 2 sites in Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Peri-implant Mucositis
Non-surgical Mechanical Debridement With or Without Full-mouth Disinfection in the Treatment of Peri-implant Mucositis
To evaluate the naturally occurring peri-implant mucositis (PM) treatment by means of non-surgical sub-marginal peri-implant instrumentation (NSPI) with or without full-mouth disinfection approach (FMD).
- Trial name
- NCT05711576
- Testing
- Full mouth disinfection
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Catania
Head-and-neck Cancer
Effects of Probiotics in Preventing Oral Mucositis
The study will be a randomized double blind prospective placebo controlled clinical study and aims to determine the therapeutic efficacy of Probiotics in Oral Mucositis pathogenesis in patients undergoing head and neck…
- Trial name
- NCT03552458
- Testing
- Lactobacillus Reuteri Oral Solution [BioGaia]
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Peri-implantitis, Dental Implants
The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices
This cross-sectional study evaluates the impact of systemic risk factors, including diabetes mellitus, smoking, cardiovascular disease, and osteoporosis, on peri-implant health status and clinical indices.
- Conditions
- Peri-implantitis, Dental Implants, Peri-implant Mucositis
- Trial name
- NCT07530211
- Testing
- Clinical and Radiographic Periodontal Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Inonu University
Mucositis, Nephrotoxicity
Treatment of Radiation and Cisplatin Induced Toxicities with Tempol
A 10 week trial to assess the ability of Tempol to prevent and/or reduce toxicities associated with cisplatin and radiation treatment in head and neck cancer patients.
- Conditions
- Mucositis, Nephrotoxicity, Ototoxicity
- Trial name
- NCT03480971
- Testing
- Tempol
- Where
- 9 sites in United States
- Volunteers
- 120 people
- Sponsor
- Matrix Biomed, Inc.
Oral Mucositis in Head and Neck Cancer
Propolis for Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer
This clinical trial evaluated whether a 15% propolis solution could delay or prevent severe oral mucositis in patients with head and neck cancer receiving radiotherapy or concurrent chemoradiotherapy.
- Trial name
- NCT07597525
- Testing
- 15% Propolis solution, Standard oral care
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ankara Oncology Research and Training Hospital
Peri-implant Mucositis
Effectiveness of Interproximal Cleaning Devices for Biofilm Removal Around Posterior Single Implants With Peri-Implant Mucositis
This randomized clinical trial aims to evaluate and compare the efficacy of different interproximal oral hygiene devices for biofilm removal around posterior single dental implants in patients diagnosed with peri-implant…
- Trial name
- NCT07393828
- Testing
- Participants assigned to this intervention group are instructed to perform daily interproximal plaque control around implant-supported crowns using the allocated interdental oral hygiene device (inter
- Volunteers
- 75 people
- Sponsor
- Universitat Internacional de Catalunya
Oral Mucositis
Prevention of Oral Mucositis in Head and Neck Cancer.
Oral Mucositis (OM) consists in the painful inflammation and ulceration of the mucous membranes lining the digestive tract, lasting between 7 and 98 days; and starts as an acute inflammation of oral mucosa, tongue, and pharynx…
- Trial name
- OMHNC-1 (NCT05853692)
- Testing
- Zinc Gluconate, Sodium Bicarbonate
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Catholic University of the Sacred Heart