Clinical trials: Mucositis
Oral Mucositis (Ulcerative) Due to Radiation, Nasopharyngeal Carcinoma (NPC)
Taurine for the Prevention and Treatment of Radiation-induced Oral Mucositis in Patients With Nasopharyngeal Carcinoma
This clinical trial aims to understand whether taurine can prevent and reduce severe radiation-induced oral mucositis in patients with nasopharyngeal carcinoma undergoing radiotherapy.
- Trial name
- NCT07567742
- Testing
- Taurine
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Sun Yat-sen University
Peri Implant Mucositis
Peri-Implant Soft Tissue and Health
Implant patients who applied to Bolu Abant İzzet Baysal University provided anamnesis. The study included 165 people with 272 implants. The study includes implants that satisfied the inclusion criteria.
- Trial name
- PSTH (NCT07564687)
- Testing
- Implant
- Where
- Turkey (Türkiye)
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Tuğba ŞAHİN
Microbial Colonization, Peri-Implantitis
Microbiome Modulation by PEMF on Plaque Induced Mucositis in Human Jaws
To evaluate the impact of Pulsed Electromagnetic Field (PEMF) on mucositis induced in humans around dental implants and correlate these possible effects with the proteomic profile of implants with and without PEMF and teeth.
- Trial name
- NCT07045636
- Testing
- Teeth wih gingivits
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jamil awad shibli
Radiation Mucositis, Staphylococcal Aureus Infection
Staph Nasal Decolonization to Improve Function and Feeding
Radiation therapy is a type of treatment that involves using radiation beams targeted at a cancer to destroy the cancer cells or slow their growth.
- Conditions
- Radiation Mucositis, Staphylococcal Aureus Infection, Head and Neck Cancer
- Trial name
- SNIFF (NCT07524894)
- Testing
- Mupirocin Ointment [Treatment]
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- David Palma
Peri-Implantitis, Peri-implant Mucositis
Peri-implantitis Implantoplasty Treatment
This double arm, split-mouth, single centre, controlled, randomised clinical study is designed to examine the effect of implantoplasty in treatment of peri-implantitis.
- Trial name
- NCT04052373
- Testing
- Implantoplasty, Open flap debridement alone
- Where
- 2 sites in Norway
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Peri-implant Mucositis
Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis
The peri-implant mucositis is an inflammatory and reversible lesion that surrounds the peri-implant mucosa without loss of supporting bone, clinically characterized by bleeding on gentle probing.
- Trial name
- NCT07047261
- Testing
- Adjunctive use of Xanthan-Chlorexidine based gel
- Where
- Italy
- Volunteers
- 182 people
- Sponsor
- University of Turin, Italy
Radiotherapy-Induced Oral Mucositis, Stomatitis
Traditional Chinese Medicine for the Prevention of Radiotherapy-Induced Oral Mucositis (RTOM)
This is a multicenter, randomized, controlled, prospective clinical trial designed to observe and evaluate the safety and efficacy of Modified Dahuang Huanglian Xiexin Mouthwash for the prevention of radiotherapy-induced oral…
- Conditions
- Radiotherapy-Induced Oral Mucositis, Stomatitis, Oral Mucositis, Radiotherapy Side Effects
- Trial name
- NCT07543978
- Testing
- Modified Dahuang Huanglian Xiexin Mouthwash
- Volunteers
- 156 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Radiation-induced Oral Mucositis, Oral Malignancy
A Phase II Prospective, Open-Label, Randomized, Multicenter Study of Kangfu Spray for the Prevention of Radiation-Induced Oral Mucositis in Patients With Oral Malignancies Receiving Intensity-Modulated Radiotherapy
This is a prospective, open-label, randomized, controlled, multicenter phase II study evaluating the efficacy and safety of Kangfu Spray for the prevention of radiation-induced oral mucositis in patients with histologically…
- Trial name
- NCT07538934
- Testing
- Kangfu Spray, Standard Oral Care
- Volunteers
- 140 people
- Sponsor
- YE ZHANG
Oral Mucositis, Quality of Life
Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.
The use of a novel topical mucosa composition (XCM-OM118) comprising 2-(trimethylazaniumyl) acetate; (2R,3R,4S)-pentane-1,2,3,4,5-pentol; Hexadecanoic acid; (9Z, 12Z)-octadeca-9,12-dienoic acid; octadecanoic acid…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- STOPOMP (NCT05635929)
- Testing
- XCM-OM118 Composition comprising olive oil, betaine and xylitol
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Mucosa Innovations, S.L.
Peri-implantitis, Dental Implants
The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices
This cross-sectional study evaluates the impact of systemic risk factors, including diabetes mellitus, smoking, cardiovascular disease, and osteoporosis, on peri-implant health status and clinical indices.
- Conditions
- Peri-implantitis, Dental Implants, Peri-implant Mucositis
- Trial name
- NCT07530211
- Testing
- Clinical and Radiographic Periodontal Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Inonu University
Oral Mucositis, Stomatitis
Amimestrocel Injection for Preventing Severe Oral Mucositis in HSCT Patients
This study aims to see if a single intravenous infusion of a cell therapy called Amimestrocel injection can help prevent severe mouth sores (oral mucositis) in patients receiving a stem cell transplant.
- Conditions
- Oral Mucositis, Stomatitis, Gastrointestinal Mucositis, Hematopoietic Stem Cell Transplantation
- Trial name
- NCT07400328
- Testing
- Amimestrocel injection
- Where
- China
- Volunteers
- 22 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Radiation-induced Oral Mucositis
Spirulina-Derived Product Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors
To evaluate the efficacy and safety of Spirulina-Derived Product for prevention and treatment of oral mucositis in patients undergoing radiotherapy for malignant head and neck tumors.
- Trial name
- NCT07040969
- Testing
- Spray of spirulina derivatives, Radiotherapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- West China Hospital
Radiation-induced Oral Mucositis
Traditional Chinese Medicine Oral Liquids and Mouthwashes for Radiation-induced Oral Mucositis in Head and Neck Cancer Patients
Evaluate the efficacy and safety of traditional Chinese medicine oral liquid and mouthwash in the treatment of radiotherapy induced oral mucositis in patients with head and neck malignancies
- Trial name
- NCT07282483
- Testing
- Qingying oral liquid and modified Da Huang-Huang Lian Xiexin mouthwash, radiotherapy
- Where
- China
- Volunteers
- 118 people
- Sponsor
- West China Hospital
Radiotherapy-induced Oral Mucositis
Traditional Chinese Medicine Preparation Alleviates Radiotherapy-induced Oral Mucositis in Head and Neck Cancer Patients.
Evaluate the effectiveness and safety of traditional Chinese medicine compound in improving radiotherapy-induced oral mucositis in patients with head and neck malignant tumors.
- Trial name
- NCT07339774
- Testing
- Zishui Daohuo oral liquid combined with Kujiu mouthwash, Radiotherapy
- Where
- China
- Volunteers
- 128 people
- Sponsor
- West China Hospital
Vaginitis, Radiotherapy Induced Mucositis
Clinical Study on the Prevention and Treatment of Radiation Vaginitis With Triethanolamine Cream
The objective of this clinical trial is to understand whether triethanolamine cream can prevent and treat acute radiation vaginitis. It will also learn about the safety of triethanolamine cream.
- Trial name
- NCT07492654
- Testing
- Trolamine (Biafine)
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Fujian Cancer Hospital
Oral Mucositis, Chemotherapy-induced Oral Mucositis
Ozone Therapy With Biomimetic Oral Care for Cancer-Related Oral Mucositis
Oral mucositis is a frequent and often debilitating complication of radiotherapy and chemotherapy, particularly in patients treated for head and neck cancers.
- Conditions
- Oral Mucositis, Chemotherapy-induced Oral Mucositis, Head and Neck Neoplasms
- Trial name
- OZOMUC (NCT07491536)
- Testing
- Gas Ozone Therapy, Biomimetic Oral Care Regimen
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Pavia
Oral Mucositis
Multi-centre, Open-label, First-in-man Study With Mucopad HA
The device´s intended use is to treat defects and/or lesions of the oral mucosa, e.g. oral mucositis.To prove safety of the device in terms of clinical results.
- Trial name
- NCT06276270
- Testing
- Mucopad HA
- Where
- 5 sites in Czechia
- Volunteers
- 50 people
- Sponsor
- Contipro Pharma a.s.
Oral Mucositis
Prevention of Oral Mucositis in Head and Neck Cancer.
Oral Mucositis (OM) consists in the painful inflammation and ulceration of the mucous membranes lining the digestive tract, lasting between 7 and 98 days; and starts as an acute inflammation of oral mucosa, tongue, and pharynx…
- Trial name
- OMHNC-1 (NCT05853692)
- Testing
- Zinc Gluconate, Sodium Bicarbonate
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Catholic University of the Sacred Heart
Radio Dermatitis, Mucositis Oral
Using Red Light Therapy to Ease Skin Side Effects and Mouth Side Effects, in Children and Young People Aged 0 to 16 Years Old, Receiving Radiotherapy
The goal of this interventional study is to see if the daily use of red light therapy called photobiomodulation can help sore skin and sore mouths in children having radiotherapy.
- Conditions
- Radio Dermatitis, Mucositis Oral, Oesophagitis
- Trial name
- RADIANT (NCT07183267)
- Testing
- Photobiomodulation
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- The Christie NHS Foundation Trust
Oral Mucositis
Efficacy of High-Level Laser Therapy in Managing Oral Mucositis Among Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation
The goal of this clinical trial is to learn if high-level laser therapy can manage oral mucositis in pediatric patients undergoing hematopoietic bone marrow transplantation.
- Trial name
- NCT07436650
- Testing
- high power laser therapy, Basic oral care
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Ain Shams University