Clinical trials: Moyamoya Syndrome
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Carotid Artery, Internal
Internal Carotid Artery Blood Flow in Pediatric Moyamoya Patients
Little is known about how general anesthesia-induced decrease in cerebral blood flow in pediatric moyamoya pateints. We investigated this question in patients undergoing moyamoya surgery, hypothesizing that cardiorespiratory…
- Trial name
- NCT04134221
- Testing
- Ultrasound assessment
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Moyamoya Disease
The Safety and Efficacy of RIC on Adult Moyamoya Disease
There are a series of symptoms such as ischemic stroke、transient ischemic attack 、hemorrhagic stroke、headache 、seizure and so on in moyamoya disease( MMD) patients .Nowadays, revascularization is the only effective way for…
- Trial name
- RIC-AMD (NCT04012268)
- Testing
- RIC, Aspirin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Stroke, Transient Ischemic Attack
Angiogenic Markers in Cerebrovascular Disease (ANFIS)
Intracranial atherosclerosis (ICAS) is the most common cause of stroke worldwide. It carries a worse prognosis than other stroke etiologies, with an annual rate of recurrent stroke and death of 15% despite intensive medical…
- Conditions
- Stroke, Transient Ischemic Attack, Atherosclerosis, Intracranial Arterial Stenosis
- Trial name
- ANFIS (NCT04240119)
- Testing
- According to current clinical care standards
- Volunteers
- 300 people
- Sponsor
- Cedars-Sinai Medical Center
Ischemic Heart Disease, Cardiac Arrest
Registry of Multicenter Brain-Heart Comorbidity in China
This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program.
- Conditions
- Ischemic Heart Disease, Cardiac Arrest, Atrial Fibrillation, Heart Failure
- Trial name
- BHC-C (NCT05961748)
- Testing
- Multi-disciplinary assessment
- Where
- 14 sites in China
- Volunteers
- 100,000 people
- Sponsor
- Beijing Tiantan Hospital
CADASIL, CADASIL (Diagnosis)
RAre, But Not aLone: a Large Italian Network to Empower the Impervious diaGNostic Pathway of Rare cerEbrovascular Diseases (ALIGNED)
Cerebrovascular diseases (CVDs) are one leading cause of morbidity and mortality worldwide. Despite intensive investigations, more than 30% of strokes remain of undetermined origin.
- Conditions
- CADASIL, CADASIL (Diagnosis), Moya Moya Disease, Moyamoya
- Trial name
- ALIGNED (NCT06935578)
- Where
- 17 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Moyamoya, Stroke
The Adult Hemorrhagic Moyamoya Surgery Study
The aim of this study is to investigate whether extracranial-intracranial(EC-IC) bypass surgery could prevent rebleeding and improve neurological function in adult moyamoya with hemorrhagic onset.
- Trial name
- AHMSS (NCT02319980)
- Testing
- Extracranial-intracranial bypass surgery
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Huashan Hospital
Moya Moya Disease
Moya Moya Syndrome With or Withtout Sickle Cell Disease
Moya Moya disease or syndrome ar characterized by a progressive or occlusion of the intracranial carotid arteries and their mainproximal branches, followed by the development of fragile neovessels at the base of the skull, leding…
- Trial name
- BMM-ScD (NCT05050344)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Cerebrovascular Accident, Moyamoya Disease
Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients
Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya disease and stroke patients
- Trial name
- NCT01419275
- Testing
- Xenon contrast agent, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pain
Goal-directed Analgesia Using ANI During General Anesthesia in Children With Moyamoya Disease
Analgesia Nociception Index (ANI) has been proposed for the evaluation of the nociception-antinociception balance in the perioperative period.
- Trial name
- NCT05672212
- Testing
- ANI (Analgesia/Nociception Index) monitoring, standard monitoring, Sufentanil
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Moyamoya Disease, Pediatrics
Effect of Recombinant Human EPO on the Postoperative Neurologic Outcome in Pediatric Moyamoya Patients
This study evaluates the effect of recombinant human erythropoietin (rHuEPO) on the neovascularization of pediatric moyamoya disease patients.
- Conditions
- Moyamoya Disease, Pediatrics, Cerebrovascular Disorders
- Trial name
- NCT03882060
- Testing
- erythropoietin, Normal saline
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Moyamoya Disease
Treatment of Moyamoya Disease With iPSC-derived Exosomes
Moyamoya disease is a cerebrovascular disease clinically characterized by chronic progressive stenosis or occlusion at the ends of bilateral internal carotid arteries and the origin of anterior cerebral arteries and middle…
- Trial name
- NCT07065409
- Testing
- iPSC-EVs
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Huaqiu Zhang
Moyamoya Disease, Healthy
Cognitive-Motor Incorporated Training and Its Relations in Cerebrovascular Diseases With Cognitive and Motor Impairments
The following three-part proposal will explore the impact of applying motor-cognitive incorporated training (MCIT) in individuals with post-stroke cognitive impairment (PSCI) or Moyamoya disease (MMD), and examine the…
- Conditions
- Moyamoya Disease, Healthy, Stroke
- Trial name
- NCT07144930
- Testing
- MCIT program, Motor training program
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Moyamoya Disease, Remote Ischemic Preconditioning
Effects of Remote Ischemic Pre-Conditioning in Moyamoya Disease Patients
In the present study, investigators evaluated whether RIPC reduce the major neurological complications in adult moyamoya disease patients undergoing encephaloduroarteriosynangiosis (EDAS).
- Trial name
- RIME (NCT04064658)
- Testing
- Remote ischemic preconditioning, Encephaloduroarteriosynangiosis
- Where
- 2 sites in China
- Volunteers
- 328 people
- Sponsor
- Beijing Tiantan Hospital
Smooth Muscle Dysfunction Syndrome (SMDS)
Nicotinamide Riboside (NR) to Treat Moyamoya-like Cerebrovascular Disease in Smooth Muscle Dysfunction Syndrome (SMDS)
The purpose of this study is to determine whether SMDS patients treated with NR at the proposed dose exhibit decreased glucose uptake in the aorta, to determine if NR treatment results in measurable changes of blood NAD+ and NR…
- Trial name
- NCT06280482
- Testing
- Nicotinamide riboside (NR)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Moyamoya
Characteristics and Outcomes of Childhood Moyamoya in the UK
This is a study to ascertain the number of children with moyamoya in the UK, their presenting features, clinical course and outcomes.
- Trial name
- NCT02434302
- Where
- United Kingdom
- Volunteers
- 98 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Moyamoya Disease
Efficacy and Safety of rTMS for Cognitive Rehabilitation in Moyamoya Disease
The purpose of this study is to evaluate the safety and effectiveness of transcranial magnetic stimulation (TMS) therapy in moyamoya patients who received surgical revascularization.
- Trial name
- NCT03543748
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 50 people
- Sponsor
- Huashan Hospital
Moyamoya Disease
The Symani Restore Study
A research study for a neurosurgical procedure in adult patients with Moyamoya disease
- Trial name
- NCT07140731
- Testing
- Symani Surgical System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Jacobs institute
Moyamoya Disease, Moyamoya Syndrome
Chinese Herbal Therapy (Qiqi Shengmai Formula) for Moyamoya Vasculopathy: The CHIMES Trial
Patients diagnosed with moyamoya vasculopathy by imaging and classified as having the Traditional Chinese Medicine (TCM) syndrome of liver-yang hyperactivity will be enrolled.
- Trial name
- NCT07286110
- Testing
- Traditional Chinese Medicine (TCM) Treatment, Conventional medical treatment
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fudan University
Moyamoya Disease, Pediatric
Safety and Efficacy of RIC in Pediatric Moyamoya Disease Patients Treated With Revascularization Therapy
Revascularization surgery has been the standard treatment to prevent ischemic stroke in pediatric Moyamoya disease (MMD) patients with ischemic symptoms.
- Trial name
- RIC-PMD (NCT03546309)
- Testing
- RIC group, Medication group
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Capital Medical University