Clinical trials: Motor Learning
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Cerebral Palsy
Motor Learning in People With Cerebral Palsy by Using Virtual Reality.
Cerebral Palsy (CP) is a group of permanent disorders that affect movement and posture due to a non-progressive lesion in the immature brain occurring in fetal brain development or in infancy.
- Trial name
- NCT03348943
- Testing
- Right hemiparesis, right upper limb., Right hemiparesis, left upper limb, Left hemiparesis, left upper limb
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Stroke
Exercise and Motor Learning After Stroke (Study #3)
Subjects with chronic stroke (> 6 months post-stroke) will learn a new walking pattern through distorted visual feedback. Retention of the pattern will be tested without visual feedback immediately after learning and 24 hours…
- Trial name
- NCT03726047
- Testing
- Exercise
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Delaware
Physical Activity, Adolescents
Effectiveness of a Multicomponent Intervention to Promote Physical Activity Levels During the School Day (MOVESCHOOL)
Study based a multicomponent school-based intervention during the school-day (i.e., Physically active learning, active breaks, and active recess) on Physical Activity, health, educational, and cognition outcomes in adolescents.
- Conditions
- Physical Activity, Adolescents, Physical Fitness, Cognition
- Trial name
- MOVESCHOOL (NCT06254638)
- Testing
- Multicomponent school-based intervention.
- Where
- Spain
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Parkinson Disease
Exogenous Effects of Standard Medical Care (Dopamine) on Motor Learning of an Upper Limb Task in Parkinson Disease
The study determines whether standard medical care (dopamine) affects learning and retention of an upper limb feeding task in people with Parkinson's disease (PD) and whether training on the feeding task generalises to…
- Trial name
- NCT02600858
- Testing
- Upper limb feeding training
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Utah
Speech, Motor Activity
Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning
These studies test the hypothesis that frontal areas of the brain participate in the cortical networks involved in the somotosensory processing that happens during speech motor learning.
- Trial name
- BRAVA² (NCT04547569)
- Testing
- Speech adaptation, Vibrotactile Discrimination, fMRI
- Where
- France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Allograft
Cooking Education and Adapted Physical Activity in Allografted Patients
Majority of patients after allo stem cell transplantation have malnutrition and decrease of physical activities. This state impacts on quality of life and on outcome of some complications like infections, graft versus host…
- Trial name
- NUTRITION (NCT03829072)
- Testing
- Cooking Education, adapted physical activity
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Amyotrophic Lateral Sclerosis (ALS)
A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)
This is a multicenter, randomized, double-blind, placebo-controlled, parallel group Phase II study to evaluate the efficacy and safety of VHB937 in participants with early-stage ALS (within 2 years of ALS symptoms onset).
- Trial name
- ASTRALS (NCT06643481)
- Testing
- VHB937
- Where
- 74 sites in United States, Australia and 15 more
- Volunteers
- 251 people
- Sponsor
- Novartis Pharmaceuticals
Cardiovascular Diseases, Cancer
Promoting Healthy Lifestyles Among Firefighters
Promoting Healthy Lifestyles: Alternative Models' Effects (PHLAME) is a research study to evaluate and compare two ways to promote healthy behaviors, (regular physical activity, less than 30% calories from fat, 5 or more servings…
- Conditions
- Cardiovascular Diseases, Cancer, Physical Activity, Nutrition
- Trial name
- PHLAME (NCT00006181)
- Testing
- Team-based intervention, One-on-one intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Exercise, Diet
Game on Philly: Engaging Underserved Middle School Youth in Out-of- School Time Sports and Nutrition Education
Game on Philly is a multi-component out-of-school time intervention delivered by trained sport-based youth development coaches and health navigators using evidenced-based programming.
- Trial name
- NCT04975529
- Testing
- Game on Philly: Engaging Underserved Middle School Youth in Out-of- School Time Sports and Nutrition Education
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Temple University
Stroke
Motor Learning of a Planning Task in Stroke Patients: the Maze Paradigm Measured Through Time and Error as Variables
The purpose of this study is to investigate the process of acquiring a motor skill subject in post-stroke, comparing them with healthy subjects.
- Trial name
- NCT00740402
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculdades Metropolitanas Unidas
Gross Motor Development Delay
Video-based Assessment of Preschool Children's Gross Motor Development
Artificial intelligence (AI) is currently one of the global focal points for industrial development, with its applications in healthcare steadily increasing, such as in disease prediction, image diagnosis, and drug development.
- Trial name
- NCT07054437
- Testing
- Gross Motor Development Screening Tool
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- Chang Gung Memorial Hospital
Motor Activity
Investigating Motor Cortex Processing for Pain Modulation
The purpose of this study is to investigate the effects of different types of interventions (motor learning, somatosensory learning, observation task, mental imagery and tDCS) on the perception of pain and motor cortex…
- Trial name
- NCT01404039
- Testing
- Motor Learning, Somatosensory Learning, Observational Task
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Frailty, Disability Physical
Viability of an Educational Program for Lifestyle Changes and an Algorithm for the Derivation of Exercise Programs in Older People at Risk of Dependency at Primary Care.
According to the INE in 2021, more than 9 million people are currently over 65 years of age. This means that more than 1 million are frail and almost 4 million are pre-fragile only in Spain.
- Conditions
- Frailty, Disability Physical, Old Age; Atrophy
- Trial name
- PRICA-POWFRAIL (NCT05772910)
- Testing
- EDUcation, EXERcise, EDU-EXER
- Volunteers
- 110 people
- Sponsor
- University of Cadiz
Behavioral Intervention
Michigan Driver Education Study
Teens are at high risk for traffic violations and car crashes because of their young age, lack of driving experience, and exposure to high-risk driving conditions.
- Trial name
- NCT00340470
- Testing
- Driver Education
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Health Promotion
Effects of the Health Promotion Program on Health Literacy, Physical and Mental Health Status, and Quality of Life
This study aims to evaluate the physical and mental health status, prevalence of chronic diseases, health literacy, and health behaviors of residents in Gandaki Province, Nepal, and to assess the effectiveness of a…
- Trial name
- NCT07306520
- Testing
- Health education, Auricular acupressure, Exercise
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Stroke
Understanding Motor Function in Stroke Patients and Their Functional Brain Reorganization Using Ultra High-field MRI
The MOTIF-STROKE study is embedded within the BrainSync project, aiming to develop innovative strategies for motor rehabilitation of the upper limb.
- Trial name
- MOTIF-STROKE (NCT07339813)
- Testing
- Functional MRI (fMRI) Acquisition
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Stroke, Acute, Stroke, Subacute
Bimanual Motor Skill Learning in Acute Stroke
The subacute phase of stroke provides a window into how a lesion perturbs sensorimotor functions prior to reorganisation driven by plasticity and neurorehabilitation.
- Trial name
- MLAS4 (NCT05760846)
- Testing
- REAplan®, Dextrain Manipulandum®
- Where
- 2 sites in Belgium
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Aging
Effect of Aging on Cortical Excitability and Motor Learning
The objective of the current proposal is to identify 1) how aging-related changes in GABAergic cortical inhibition affect motor performance, and 2) how aerobic exercise may improve inhibitory function and facilitate motor…
- Trial name
- ACE (NCT03750903)
- Testing
- Aerobic Exercise, Stretching and Balance Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Amyotrophic Lateral Sclerosis
A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Participants With Superoxide Dismutase 1 (SOD-1) Amyotrophic Lateral Sclerosis (ALS)
In this study, researchers will learn more about the safety of tofersen, also known as Qalsody®. This is a drug available for doctors to prescribe for participant with a certain type of amyotrophic lateral sclerosis, also known…
- Trial name
- NCT07259980
- Testing
- Tofersen
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Biogen