Clinical trials: Motor Evoked Potential
Spine Disease
Effect of Remimazolam on Motor Evoked Potential
This study was planned to investigate the degree of effect of remimazolam on MEP compared to propofol when monitoring the motion-inducing potential (MEP).
- Trial name
- NCT05453955
- Testing
- Propofol, Remimazolam Besylate
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Korea University Guro Hospital
Healthy Subjects
Cortical Effects of Peripheral Proprioceptive Stimulation on the Motor Evoked Potentials of the Limbs
Through motor muscle potentials, we will observe how a peripheral somatosensory mechanical stimulus on key limb musculature communicates signals via afferent sensory fibers that encode proprioceptive signals from muscle spindles…
- Trial name
- NCT06936579
- Testing
- proprioceptive stimulation
- Where
- Spain
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Facultat de ciencies de la Salut Universitat Ramon Llull
Spinal Cord Injury Cervical, Spinal Cord Injury, Acute
Upper Limb Rehabilitation Using Non-invasive Spinal Cord Stimulation
The goal of this RCT study is to evaluate if combining activity-based therapy (ABT) with transcutaneous spinal cord stimulation (tSCS) can improve recovery of arm and hand movement in people with cervical spinal cord injury…
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injury, Acute, Spinal Cord Injury (Quadraplegia)
- Trial name
- CIME_upperlimb (NCT07361627)
- Testing
- Protocol 2: Combination of activity-based therapy and facilitatory transcutaneous spinal cord stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
MEP Onset Latency
Deep Brain Stimulation (DBS) and Motor Evoked Potentials (MEP)
MEP onset latencies from the hand muscle using two different stimulus methods will be compared from each study participant. Conventional MEP data will be collected prior to skin incision.
- Trial name
- DBS MEP (NCT05569213)
- Testing
- motor evoked potentials
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Stroke, Aphasia
Electro-physiological Signs to Prognostic Aphasia Recovery After a Stroke
The purpose of this study is to study, among the aphasic person, if motor function ( studied by Motor Evoked Potentials) performed within the first 14 days after a stroke can predict a good recovery from aphasia 6 months of the…
- Trial name
- APHA-TMS (NCT03103230)
- Testing
- Cortical magnetic stimulation
- Where
- France
- Volunteers
- 130 people
- Sponsor
- University Hospital, Bordeaux
Transcranial Direct Current Stimulation, Motor Evoked Potential
Effects of Transcranial Oscillatory Direct Current Stimulation on the Functions of Cerebral Cortex in Healthy Subjects
To investigate the effect of transcranial oscillatory direct current stimulation on functions of cerebral cortex (cortical excitability and frequency of eeg) in healthy subjects
- Conditions
- Transcranial Direct Current Stimulation, Motor Evoked Potential, Healthy Subjects
- Trial name
- NCT06076044
- Testing
- toDCS 2mA 1Hz, toDCS 2mA 10Hz, tDCS 1mA
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Hebei Medical University
Spinal Plasticity
Combining PAS to Non-invasive VNS
Vagus nerve stimulation (VNS) and paired associative stimulation (PAS) have been shown to have efficacy in improving the results of motor rehabilitation after stroke and spinal cord injury, respectively.
- Trial name
- NCT04938284
- Testing
- PAS, VNS
- Where
- Finland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Postoperative Nausea
Effect of Fosaprepitant on Motor Evoked and Somatosensory Evoked Potentials Under General Anesthesia
The purpose of this study is to determine if intravenous fosaprepitant can interfere with nervous system monitoring signals in patients having surgery under general anesthesia.
- Trial name
- NCT03197064
- Testing
- Fosaprepitant 150 mg
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stanford University
Stroke, Upper Limb Paresis
Effects of High-Frequency rTMS on Cortical Motor Mapping in Stroke Patients With Severe Upper Limb Impairment (MAP2024SJD)
The goal of this clinical trial is to learn if a single session of high-frequency repetitive transcranial magnetic stimulation (rTMS) can increase cortical motor activity in stroke patients with severe upper limb impairment.
- Trial name
- MAP2024SJD (NCT07787793)
- Testing
- High-frequency repetitive transcranial magnetic stimulation
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Ancor Rebassa Cabrera
Trauma, Nervous System
Intrathecal Morphine on Transcranial Electric Motor-Evoked Potentials
Patients undergoing posterior spinal fusion (PSF) procedures for scoliosis are at risk for iatrogenic neurologic injury of the spinal cord and/or spinal nerve roots during surgical correction of the abnormal spinal curvature.
- Trial name
- EIM (NCT00596609)
- Testing
- Intrathecal Morphine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Children's Hospital of Philadelphia
Healthy Adult Participants
Effects of Respiratory Muscle Training on Tongue Corticomotor Excitability
The tongue plays a central role in essential oral functions, including swallowing, speech, and upper airway control. Its coordinated interaction with the respiratory system is particularly relevant in clinical conditions such as…
- Trial name
- TMS-RMT (NCT07737015)
- Testing
- IMT, EMT
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Multiple Sclerosis
Validation of Multimodal Evoked Potentials (mmEP) for Predicting Disease Progression in Multiple Sclerosis
Utility of Multimodal Evoked potentials (mmEP) for monitoring disease course and prediction of progression at different stages of Multiple Sclerosis (MS) is investigated
- Trial name
- SMSC (NCT03632473)
- Testing
- multimodal evoked potentials (mmEP)
- Where
- 3 sites in Switzerland
- Volunteers
- 29 people
- Sponsor
- University Hospital, Basel, Switzerland
Spine, Pain
Effect of Magnesium on Neuromonitoring
Intraoperative neurophysiologic monitoring (IONM) is commonly used during complex spinal surgery to monitor the integrity of neural structures and improve the perioperative safety profile.
- Conditions
- Spine, Pain, Spine Surgery, Spine Surgery With Neuromonitoring
- Trial name
- MgNm (NCT06975072)
- Testing
- Magnesium sulfate administration
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Multiple Sclerosis, Weakness
Effects of the Cross-Training in Patients With Multiple Sclerosis
The purpose of this study is to determine whether, in patients with multiple sclerosis presenting with marked asymmetry of strength, training the less-affected limb with a Cross-Training approach may induce a meaningful transfer…
- Conditions
- Multiple Sclerosis, Weakness, Fatigue
- Trial name
- CTSM (NCT02010398)
- Testing
- Cross-Training healthy subjects, Cross-Training multiple sclerosis, Standard-training multiple sclerosis
- Where
- 3 sites in Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Multiple Sclerosis
Feasibility and Reliability of Multimodal Evoked Potentials in an International Multicenter Setting
Study Objectives and Endpoints: Objective: The primary objective of the study is to evaluate the feasibility and test-retest reliability of MEP's and (SSEP's) in a multicenter clinical trial in healthy subjects and subjects with…
- Trial name
- NCT03047460
- Testing
- multimodal evoked potentials
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Clinique Neuro-Outaouais
Intervertebral Disc Degeneration, Intervertebral Disc Displacement
Comparison of Three Approaches of Electrode Placement to Detect Changes in Motor Evoked Potentials During Spine Surgery
Motor Evoked Potentials are an aspect of intraoperative neuromonitoring, a tool used by neurophysiologists during surgery to prevent irreversible damage to the spinal cord during procedures.
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Stenosis, Spinal Curvatures
- Trial name
- NCT05098431
- Testing
- Quadriceps and Rectus Femoris MEP Recording
- Where
- United States
- Sponsor
- Allina Health System
Motor Evoked Potential
The Effect of Balanced Anesthesia Regimen on Intraoperative Trans-cranial Motor Evoked Potential During Spine Surgeries:
transcranial motor evoked potentials (TcMEP) were proved to be useful during complicated spinal surgeries to prevent iatrogenic complications. The effect of anesthetic agents was comprehensively discussed in literature.
- Trial name
- NIOM (NCT04997707)
- Testing
- Propofol Abbott, Sevoflurane Inhalation Solution, transcranial motor evoked potential(Tcm
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- El-Sahel Teaching Hospital
Stroke, Upper Extremity Paresis
rTMS Combined With Motor Training for the Treatment of Upper Limb Motor Dysfunction in Stroke Patients
The goal of this clinical trials is to investigate the effectiveness of online repetitive transcranial magnetic stimulation (rTMS) in enhancing upper limb motor rehabilitation during the subacute and chronic phase of stroke.
- Trial name
- NCT06752499
- Testing
- Online stimulation, Offline stimulation
- Where
- 3 sites in China
- Volunteers
- 60 people
- Sponsor
- Ruijin Hospital
Spine Surgery, Intraoperative Neurophysiological Monitoring
Low-Dose Rocuronium Maintenance During Spine Surgery With Intraoperative Neurophysiological Monitoring
This randomized controlled trial will compare two strategies for rocuronium use during general anesthesia for spine surgery with intraoperative neurophysiological monitoring.
- Conditions
- Spine Surgery, Intraoperative Neurophysiological Monitoring, Neuromuscular Blockade
- Trial name
- ROC-IONM (NCT07627750)
- Testing
- Low-Dose Rocuronium Maintenance, Rocuronium
- Where
- Vietnam
- Volunteers
- 62 people
- Sponsor
- Bach Mai Hospital
Healthy Volunteers, Constipation
Investigation of Cortico-Rectal Pathways in Healthy Subjects and Constipated Patients
Biofeedback therapy improves bowel symptoms and anorectal function in patients with dyssynergic defecation, however its mechanism of action is not known.
- Trial name
- NCT01300897
- Testing
- Cortical Evoked Potentials, Transcranial motor evoked potentials, Translumbosacral motor evoked potentials
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Augusta University