Clinical trials: Motivation
Chronic Low Back Pain, Posttraumatic Stress Disorder
Exercise Maintenance in Chronic Pain and PTSD
The primary purpose of the R21 is using an experimental medicine research approach to study whether a chronic, progressive-based exercise program will help Veterans suffering from chronic low back pain (cLBP) and PTSD achieve…
- Trial name
- NCT03644927
- Testing
- Progressive exercise training, Waitlist Control
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston University
Cervical Cancer, Tobacco Use
Smoking Cessation for Cervical Cancer Survivors
The goal of this research study is to compare a program called Motivation And Problem-Solving (MAPS) to the standard treatment to help participants with a history of cervical cancer or high-grade cervical dysplasia quit smoking.
- Conditions
- Cervical Cancer, Tobacco Use, Smoking Cessation
- Trial name
- NCT02157610
- Testing
- Self-Help Materials, Nicotine Patch, REDCap
- Where
- 3 sites in United States
- Volunteers
- 202 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Smoking, Smoking Cessation
Evaluation of Treatments to Improve Smoking Cessation Medication Adherence
Many smokers fail to take their smoking cessation medication as recommended. This research is designed to identify treatments that improve the use of cessation medications and to determine whether an increase in medication use…
- Conditions
- Smoking, Smoking Cessation, Adherence, Nicotine Dependence
- Trial name
- Adherence (NCT01120704)
- Testing
- Short Term Combination Nicotine Replacement Therapy (patch + gum), Long Term Combination Nicotine Replacement Therapy (patch + gum), Intensive Maintenance Counseling
- Where
- United States
- Volunteers
- 544 people
- Sponsor
- University of Wisconsin, Madison
Health Risk Behaviors, Risk Reduction Behavior
Enhancing Quality in Protective Strategies
The most successful young adult alcohol or marijuana interventions involve the provision of accurate, nonjudgmental personalized feedback, but notably the inclusion and effectiveness of protective behavioral strategies (PBS)…
- Trial name
- EQUIP (NCT04978129)
- Testing
- Online and Text Messaging Intervention
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Major Depressive Disorder, Bipolar Disorder
Brain Mechanisms of Human Motivation
This study aims to investigate reward learning across the mood disorder spectrum and to investigate the predictive validity of reward learning for subsequent symptom severity.
- Trial name
- NCT01976975
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Ischemic Heart Disease, Hopelessness
Reducing Hopelessness Through Improved Physical Activity in Adults With Heart Disease: With COVID-19 Considerations
After a 30-year decline, heart disease is projected to increase up to 18% by 2030. Participation rates in cardiac rehabilitation remain extremely low and hopeless individuals are less likely to participate.
- Conditions
- Ischemic Heart Disease, Hopelessness, Physical Activity, Motivation
- Trial name
- Heart Up! (NCT03907891)
- Testing
- Motivational social support from nurse, Motivational social support from nurse with additional support from significant other, Attention control
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- University of Illinois at Chicago
Physical Activity, Motivation
Effect of Sport Education in University Required PE on Students' Perceived Physical Literacy and Physical Activity Level
This project examines the effects of implementing sport education model in university required physical education lessons on perceived physical literacy and physical activity levels of the students.
- Trial name
- NCT03888885
- Testing
- Sport Education Model
- Where
- Hong Kong
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Major Depressive Disorder
Imaging Dopamine Release in Depression
This study aims to determine whether ventral striatal dopamine release is a mechanism of reward motivation in major depression, whether dopamine release is low in depression, and whether DA release and reward motivation predict…
- Trial name
- NCT02033369
- Testing
- Pramipexole
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Cocaine Abuse, Cocaine Dependence
n-Acetylcysteine and Cocaine
This study will determine the initial efficacy, safety and tolerability of n-acetylcysteine as a pharmacotherapy for cocaine dependence.
- Trial name
- NCT02141620
- Testing
- Cocaine, n-Acetylcysteine
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Stress, Psychological, Motivation
Brain and Stress Study
Motivational deficits such as anhedonia are core to several psychiatric disorders and underlie significant functional impairment.
- Trial name
- BASS (NCT06044090)
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Obesity, Adolescent, Health Behavior
Health Literacy and Obesogenic Behaviors
The prevalence of adolescent behaviors that can lead to obesity are alarming, and reduced life expectancy is the future of America's youth if behavioral changes are not implemented to improve health and reduce the obesity burden.
- Conditions
- Obesity, Adolescent, Health Behavior, Health Knowledge, Attitudes, Practice, Diet, Healthy
- Trial name
- HL-Squared (NCT04252677)
- Testing
- Obesity Prevention, Health Literacy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health
Infant Development, Motivation
Infant Environment Study
This study evaluates the effect of a music enhancement program to strengthen the motivation to engage in music related behaviors rather than eating in infants who are high in motivation to eat.
- Trial name
- NCT02936284
- Testing
- Music Enhancement, Play Date
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Depressive Symptoms
Blueberries, Inflammation, Motivation, and Physical Activity
The purpose of this study is to determine the feasibility and preliminary efficacy of daily supplementation of freeze-dried blueberry to modulate inflammation-driven lack of motivation in 40 sedentary, older adults with…
- Trial name
- NCT05735587
- Testing
- Freeze-dried Blueberry Powder
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Hebrew SeniorLife
HPV Vaccination, Vaccine; Uptake
PREVENT HPV-Related Cancers - BootCamp Translation
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Vaccine; Uptake, Vaccination; Series Completion
- Trial name
- PREVENT (NCT06290206)
- Testing
- PREVENT - BCT
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity
Financial vs. Non-Financial Rewards for Weight Loss and Weight Maintenance
Three of every four Veterans are overweight or obese, and weight loss is associated with reduced morbidity and mortality. The VA MOVE! program for weight loss is moderately effective but only reaches a small percentage of…
- Trial name
- NCT02957539
- Testing
- Financial rewards, Non-Financial rewards
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- VA Office of Research and Development
Apathy, Stroke Sequelae
Accelerated rTMS for Post-Stroke Apathy
This pilot study will investigate the safety, feasibility, tolerability, and preliminary efficacy of accelerated high-dose repetitive transcranial magnetic stimulation (rTMS) targeting the medial prefrontal cortex (mPFC) to…
- Conditions
- Apathy, Stroke Sequelae, Stroke (CVA) or TIA, Stroke/Brain Attack
- Trial name
- NCT05878457
- Testing
- MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina
Behavior and Behavior Mechanisms
Translational Research to Inform Interventions for Challenging Behavior
This project is meant to identify relations between the reinforcement histories of 80 adults with intellectual and developmental disabilities (IDD) and the prevalence of extinction bursts.
- Trial name
- NCT04842500
- Testing
- Demand Informed Moderator Analysis
- Where
- 5 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Alcohol Abuse
Computer-delivered Screening and Brief Intervention for Alcohol Use in Pregnancy
The purpose of this study is to lay the ground work for a fully powered clinical trial of a computer-delivered screener and intervention for alcohol use during pregnancy. The pilot study will include: 1.
- Trial name
- NCT01643044
- Testing
- Computer-delivered, brief intervention on alcohol use
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Wayne State University
Substance Abuse, Intravenous, HIV
Change the Cycle: An RCT to Prevent Injection Initiation
The study will test the efficacy of a hour long, one-on-one, active listening counseling session (called Change the Cycle or CTC) aimed at reducing behaviors among active people who inject drugs (PWID) that research has found to…
- Conditions
- Substance Abuse, Intravenous, HIV, Heroin Dependence, Opioid Dependence
- Trial name
- CTC (NCT02774954)
- Testing
- Change the Cycle
- Where
- 2 sites in United States
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Sedentary Behavior, Exercise
Multiphase Optimization Trial of Incentives for Veterans to Encourage Walking
Regular physical activity (PA) is essential to healthy aging. Unfortunately, only 5% of US adults meet guideline of 150 minutes of moderate exercise; Veterans and non-Veterans have similar levels of PA.
- Conditions
- Sedentary Behavior, Exercise, Walking, Motivation
- Trial name
- NCT04518943
- Testing
- Walking
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- VA Office of Research and Development