Clinical trials: Morbidity of CVD
oPAP Should be > 25mmHg in Right Heart Catheterization at Rest, There Should be Patients Who Will Undergo Non-cardiac and Non-obstetric Surgery
Postoperative Morbidity / Mortality Rates of Patients With Pulmonary Hypertension
Pulmonary hypertension (PHT) is an oPAP ≥25 mmHg as assessed by right heart catheterization at rest. It is divided into 5 groups according to its etiology and mechanism.
- Trial name
- PulmonaryHT (NCT05565911)
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Baskent University
Heart Failure
Care-HF CArdiac Resynchronization in Heart Failure
The CARE-HF trial evaluates the effects of Cardiac Resynchronization (CR) therapy on the mortality and morbidity of patients with heart failure due to left ventricular systolic dysfunction already receiving diuretics and optimal…
- Trial name
- NCT00170300
- Testing
- Implantable Cardiac Resynchronisation (pacing) device
- Volunteers
- 813 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Coronary Heart Disease, Cardiovascular Disease
A Randomized Controlled Trial of Stress Reduction on Cardiovascular Morbidity and Mortality in African Americans
This randomized controlled clinical trial tests the hypothesis that a selected stress reduction approach, the Transcendental Meditation program will reduce all-cause mortality, myocardial infarction and stroke in African American…
- Trial name
- Milw (NCT01299935)
- Testing
- Transcendental Meditation, Health Education
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Maharishi International University
Coronary Atherosclerosis, Angina Pectoris
Trial of Drug Eluting Stent Versus Bare Metal Stent to Treat Coronary Artery Stenosis
Stenosis of the coronary arteries may be treated by balloon dilatation followed by the implantation of a metal stent. However, restenosis occurs in 10-20% of patients treated with bare metal stents (BMS).
- Conditions
- Coronary Atherosclerosis, Angina Pectoris, Myocardial Infarction
- Trial name
- NORSTENT (NCT00811772)
- Testing
- Percutaneous coronary intervention (PCI)
- Where
- 8 sites in Norway
- Volunteers
- 9,013 people
- Sponsor
- University of Tromso
Heart Failure, Congestive
Telmisartan in Haemodialysis Patients With Chronic Heart Failure
Background: In haemodialysis patients, chronic heart failure (CHF) is responsible for a high mortality rate but, presently, very little data is available regarding this population.
- Trial name
- NCT00490958
- Testing
- telmisartan
- Where
- Italy
- Volunteers
- 351 people
- Sponsor
- University of Campania Luigi Vanvitelli
Coronary Artery Disease
TEAM-Project: Trial on the Effect of Anesthetics on Morbidity and Mortality
Volatile anesthetics may provide some protection from myocardial ischemia, an effect called anesthetic preconditioning. In patients undergoing coronary artery bypass surgery, this preconditioning effect resulted in better cardiac…
- Trial name
- NCT00286585
- Testing
- Inhalational anesthetic, Intravenous anesthetic, propofol
- Where
- 3 sites in Switzerland
- Volunteers
- 385 people
- Sponsor
- University Hospital, Basel, Switzerland
Shock, Sepsis
Single Dose Enteral Tranexamic Acid in Critically Ill Patients
The premise of this study is that enteral tranexamic acid will help to maintain small bowel integrity, which is often compromised by critical illness due to inadequate cardiovascular perfusion (i.e., shock), and that maintenance…
- Conditions
- Shock, Sepsis, Hypotension, Critical Illness
- Trial name
- NCT01683747
- Testing
- Tranexamic Acid, Control Intervention (Carrier fluid only)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- San Diego Veterans Healthcare System
Hyperglycaemia (Non Diabetic), Enteral Feeding Intolerance
Hyperglycemia in Patients with Stroke and Indication of Enteral Nutrition
The purpose of this study is to evaluate the effect of a specific nutritional formula for diabetics on the development of hyperglycemia in patients with recent non-diabetic stroke who require admission and enteral nutritional…
- Conditions
- Hyperglycaemia (Non Diabetic), Enteral Feeding Intolerance, Stroke
- Trial name
- GlyENStroke (NCT03422900)
- Testing
- Diabetes-Specific enteral formula, Standard formula
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Endocrinology and Clinical Nutrition Research Center, Spain
Stroke
Akershus Early Mobilisation in Stroke Study
Treatment in stroke units compared with treatment in general medical wards reduces the odds of being dead or disabled. Little is known about which components of acute stroke care that is responsible for this benefit.
- Trial name
- AKEMIS (NCT00832351)
- Testing
- Mobilisation
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- University Hospital, Akershus
Pregnancy Complications, Pregnancy, High Risk
Active Pregnancy Against COVID-19
Historically and traditionally, the recommendations related to physical exercise during pregnancy have been based more on moral or cultural issues than on scientific evidence.
- Conditions
- Pregnancy Complications, Pregnancy, High Risk, Pregnancy Induced Hypertension, Newborn Morbidity
- Trial name
- ACPREGCOV (NCT04563065)
- Testing
- Exercise program, Healthy lifestyle advise
- Where
- 2 sites in Spain
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidad Politecnica de Madrid
Hyperthyroidism, Cardiovascular Diseases
Follow-up Study of the RAI-Treated Hyperthyroid Patients
Previous studies of hyperthyroid patients suggest that they remain at increased risk of cardiovascular morbidity after restoring euthyroidism.
- Conditions
- Hyperthyroidism, Cardiovascular Diseases, Atrial Fibrillation
- Trial name
- NCT00471458
- Where
- Finland
- Volunteers
- 5,222 people
- Sponsor
- Tampere University
Heart Failure
GISSI-HF- Effects of n-3 PUFA and Rosuvastatin on Mortality-Morbidity of Patients With Symptomatic CHF
INTRODUCTION While pharmacological treatments specifically targeted to the cardio-circulatory system have been largely investigated, scanty controlled data are available concerning the role of dietary and metabolic approaches in…
- Trial name
- NCT00336336
- Testing
- n-3 PUFA, Rosuvastatin
- Where
- 337 sites in Italy, Switzerland
- Volunteers
- 6,975 people
- Sponsor
- Gruppo di Ricerca GISSI
Brain Injuries, Congenital Heart Disease
Protecting Brains and Saving Futures - the PBSF Protocol
Background: Multiple neonatal disorders are associated with risks of neurological injury. Thus, management of these infants should involve a coordinated approach to permit early diagnosis with improved clinical care.
- Conditions
- Brain Injuries, Congenital Heart Disease, Newborn Morbidity, Intraventricular Hemorrhage
- Trial name
- PBSF (NCT03786497)
- Where
- 2 sites in Brazil
- Volunteers
- 2,268 people
- Sponsor
- Protecting Brains Saving Futures
Heart Failure，Congestive
RELieving Increasing oEdema Due to Heart Failure
This trial will investigate the potential for patiromer-facilitated use of higher doses of mineralocorticoid antagonists in addition to standard care (compared to standard care alone) to improve congestion, well-being and…
- Trial name
- RELIEHF (NCT04142788)
- Testing
- Patiromer
- Where
- 11 sites in United Kingdom
- Volunteers
- 19 people
- Sponsor
- NHS Greater Glasgow and Clyde
Cardiovascular Disease
Tolerance of "on Line" Hemodiafiltration in Chronic Renal Failure Patients
The aim of this study is to appreciate the tolerance of "on line" hemodiafiltration and its impact on morbidity and cardiovascular risk factors in chronic renal failure patient.
- Trial name
- on-line-HDF (NCT01327391)
- Testing
- On line Hemodiafiltration, Hemodialysis
- Where
- France
- Volunteers
- 415 people
- Sponsor
- University Hospital, Montpellier
Prostate Cancer, Metabolic Syndrome
Akkermansia Muciniphilia and Metabolic Side Effects of ADT
The overriding objectives of this study are: 1. Primary outcomes: 1. To confirm that administration of oral acetate increases the proportion of A.
- Conditions
- Prostate Cancer, Metabolic Syndrome, Obesity, Cardiovascular Morbidity
- Trial name
- NCT05802121
- Testing
- Apple Cider Vinegar
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University
Subarachnoid Hemorrhage (SAH), Tachycardia
Impact of Tachycardia on Outcome After Subarachnoid Hemorrhage (SAH)
The purpose of this retrospective study is to test the hypothesis that uncontrolled tachycardia serves as a risk factor for adverse cardiovascular events and poor outcome after Subarachnoid Hemorrhage (SAH).
- Trial name
- NCT01585311
- Where
- United States
- Volunteers
- 1,540 people
- Sponsor
- Columbia University
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
Evaluation of Remote Patient Monitoring.
Nottingham Primary Care Trust has launched telemonitoring to support: independent living and self-management ability of people with congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD) and co-morbidities…
- Trial name
- NCT00789100
- Where
- United Kingdom
- Sponsor
- Brunel University
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Pulmonary Hypertension, Sickle Cell Anemia
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
The purpose of this study is to determine how often people with sickle cell anemia develop pulmonary hypertension a serious disease in which blood pressure in the artery to the lungs is elevated.
- Conditions
- Pulmonary Hypertension, Sickle Cell Anemia, Sickle Cell Disease
- Trial name
- NCT00011648
- Where
- 2 sites in United States
- Volunteers
- 986 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)