Clinical trials: Morbid Obesity, open to volunteers
Obesity, Morbid
Bariatric Surgery and Pharmacokinetics of Amlodipine
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines.
- Trial name
- NCT02904291
- Testing
- Amlodipine
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Norwegian University of Science and Technology
Obesity, Morbid, GERD
Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB
Evaluation of the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass (OAGB)
- Conditions
- Obesity, Morbid, GERD, Ulcer, Gastric
- Trial name
- BiFLux (NCT04422405)
- Testing
- One Anastomosis Gastric Bypass (OAGB)
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Spital Limmattal Schlieren
Chronic Knee Pain, Obesity, Morbid
Photobiomodulation in Chronic Knee Pain in Patients Who Are in PreRehabilitation for Bariatric Surgery
Chronic pain is a global public health problem, which intensifies even more in the obese population, reaching about 33% of these patients.
- Trial name
- NCT05816798
- Testing
- Photobiomodulation, Standard Physiotherapy Tretament
- Where
- Brazil
- Volunteers
- 62 people
- Sponsor
- University of Nove de Julho
Morbid Obesity, Bariatric Surgery
Exercise to Fight Obesity
This clinical trial aims to determinate whether a structured exercise program, supported by telerehabilitation, can help individuals with severe obesity who are going to undergo bariatric surgery.
- Conditions
- Morbid Obesity, Bariatric Surgery, Telerehabilitation
- Trial name
- ExFO (NCT06934681)
- Testing
- Usual Care Group, Controlled exercise with telerehabilitation
- Where
- 2 sites in Spain
- Volunteers
- 72 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Adult, Obesity, Morbid
Utilization of Airway Stabilizing Rod to Assist With Laryngeal Mask Airway Guided Fiberoptic Intubation in Adults With Obesity
The FASTER stabilizing rod offers the distinct advantage of intubating through the laryngeal mask airway with a fiberoptic scope via the FASTER stabilizing rod.
- Trial name
- FASTER (NCT06916364)
- Testing
- Fiberoptic Assisted Endotracheal Rod Intubation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obesity, Morbid
Study of the Steroid Hormone Milieu in Obese Patients
The aim of this observational study is to evaluate the actual secretion of cortisol and testosterone in obese male subjects, together with the receptor sensitivity to these hormones in order to understand whether the hormonal…
- Trial name
- MiSterO (NCT06341699)
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Istituto Auxologico Italiano
Bariatric Surgery Candidate, Obesity, Morbid
The Poor Responders Study
Obesity and type 2 diabetes are major causes of illness and premature death worldwide and their incidence is increasing rapidly. Bariatric surgery is considered as the "gold-standard" surgical treatment for both conditions.
- Conditions
- Bariatric Surgery Candidate, Obesity, Morbid, Diabetes Mellitus, Type 2
- Trial name
- NCT05404061
- Testing
- Gut hormones
- Where
- United Kingdom
- Volunteers
- 220 people
- Sponsor
- Imperial College London
Morbid Obesity
Endoscopic Gastric Tubulization
Endoscopic gastric tubulization is currently proposed in the Digestive Surgery Department of the Nouvel Hôpital Civil, Strasbourg, France, to adult patients with morbid obesity.
- Trial name
- Endosleeve (NCT03554902)
- Testing
- Endoscopic gastric tubulization
- Where
- France
- Volunteers
- 300 people
- Sponsor
- IHU Strasbourg
Morbid Obesity
Gastric Recalibration After Endoscopic Sleeve Gastroplasty
Endoscopic sleeve gastroplasty (ESG) is a technique used for bariatric surgery, with results comparable to conventional surgery, in order to treat morbid obesity.
- Trial name
- ESG-IRM (NCT04945473)
- Testing
- Endoscopic placement of additional sutures
- Where
- France
- Volunteers
- 100 people
- Sponsor
- IHU Strasbourg
Obesity, Morbid
BASUN - Risks for Malnutrition, Metabolic Bone Disease and Impaired Oral Health After Obesity Treatment
Weight-reducing obesity surgery (OS) generally gives good results but complications are common; e.g. impaired weight loss, weight regain, bowel pain, diarrhea, vitamin/mineral deficiency, osteoporosis and impaired dental health.
- Trial name
- BASUN (NCT03152617)
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Göteborg University
Morbid Obesity, Bariatric Surgery Candidate
Rivaroxaban Versus Enoxaparin for Prophylaxis of Venous Thromboembolism in Bariatric Surgery
Rivaroxaban versus enoxaparin for prophylaxis of venous thromboembolism in morbidly obese patients undergoing bariatric surgery: An open_label randomized controlled trial
- Trial name
- NCT06689241
- Testing
- Enoxaparin, rivaroxaban
- Where
- Egypt
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Obesity and Overweight, Obesity, Morbid
Impact of Nutritional Intervention With Probiotics and Prebiotics on Obesity.
Obesity is one of the most severe and prevalent non-communicable diseases worldwide, affecting an estimated one-third of the population in Spain.
- Conditions
- Obesity and Overweight, Obesity, Morbid, Metabolic Syndrome
- Trial name
- MicoBeBioticos (NCT06722443)
- Testing
- Probiotic, Prebiotic, Synbiotic
- Where
- Spain
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Morbid Obesity
Bougie Sleeve Trial
Staple-line leak is the most frequent and incapacitating complication after laparoscopic sleeve gastrectomy (LSG). The aim of this prospective randomized trial is to compare the staple-line leak rate after LSG according to the…
- Trial name
- BOUST (NCT02937649)
- Testing
- Laparoscopic sleeve gastrectomy using 48-Fr bougie, Laparoscopic sleeve gastrectomy using standard care bougie
- Where
- 12 sites in France
- Volunteers
- 1,658 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-Alcoholic Fatty Liver Disease, Metabolic Encephalopathy
Prognostic Significance of Fatty Liver Disease in Bariatric Patients
Prospective non-randomized intervention case control study on patients with a BMI > 35. The intervention group/cases (n=600) is comprised of bariatric patients who undergo bariatric surgery and the control group (n=600) of age…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Metabolic Encephalopathy, Obesity, Morbid, Non-alcoholic Steatohepatitis
- Trial name
- PROMETHEUS (NCT03535142)
- Testing
- Bariatric surgery
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Metabolic Syndrome, Severe Obesity
Endoscopic Conversion of Sleeve Gastrectomy to Single Anastomosis Sleeve-ileal Bypass (SASI) for Gastroesophageal Reflux (GERD), Primary and Secondary Non-responder.
The aim of this study is to determine the feasibility and effectiveness of endoscopic anastomosis of sleeve gastrectomy to ileum with a lumen apposing metal stent (LAMS) after a failed sleeve gastrectomy.
- Conditions
- Metabolic Syndrome, Severe Obesity, Reflux, Gastroesophageal, Bariatric Surgery
- Trial name
- NCT06757296
- Testing
- Endoscopic SASI
- Where
- 3 sites in Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore Health Services
Non-Alcoholic Fatty Liver Disease, Obesity, Morbid
Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
The study is aimed To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Obesity, Morbid, Brown Fat, Metabolic Disease
- Trial name
- NCT03875625
- Testing
- Bariatric surgery, Dietitian led life style modification intervention, Conventional care (control)
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Obesity, Obesity, Morbid
Endoscopic Treatment of Overweight and Mild Obesity with ORBERA365
INTRODUCTION: Obesity is a critical health condition associated with high rates of morbidity and mortality. Conservative therapies such as dietary restriction, physical exercise, and pharmacological treatments have not prevented…
- Trial name
- ORBERA365 (NCT06785233)
- Testing
- Non-Adjustable Intragastric Balloon, ORBERA365
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaiser Clinic and Hospital
Morbid Obesity
Effect of Oxalidine Combined with Reduced-opioid Anesthesia on Multimodal Analgesia in Morbidly Obese Patients Undergoing Bariatric Surgery
The goal of this study is to elucidate the efficacy and safety of oxelidine combined with oligopiate anesthesia for multi-modal analgesia in weight-loss surgery in morbidly obese patients, and to discover a new strategy for…
- Trial name
- NCT06712199
- Testing
- oxalidine
- Where
- China
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Yongtao Sun
NAFLD, Obesity, Morbid
Integrated Multi-omics Data for Personalized Treatment of Obesity-associated Fatty Liver Disease
The investigators seek to analyze the samples provided by patients with obesity-associated fatty liver disease at the multi-omics level and to integrate the results with clinical information, genotypic variants, and factors…
- Conditions
- NAFLD, Obesity, Morbid, Comorbidities and Coexisting Conditions
- Trial name
- NCT05554224
- Testing
- To propose diagnostic tests for liver diseases before surgical decisions.
- Where
- Spain
- Volunteers
- 1,104 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying
GLP_1 RA Ultrasound Study
The purpose of the study is to determine whether patients taking GLP-1 RAs have increased residual (left behind), gastric (stomach), contents due to delayed gastric emptying when following standard preoperative fasting guidelines.
- Conditions
- Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying, Risk of Aspiration, Diabetes
- Trial name
- NCT06581120
- Testing
- Glucagon-Like Peptide-1 receptor agonists, Point of Care Gastric Ultrasound
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati