Clinical trials: Morbid Obesity
Obesity, Morbid
Low Impact Laparoscopy In Bariatric Surgery
The goal of this clinical trial is to learn if low pressure pneumoperitoneum and small incisions (low impact laparoscopy, LIL) works to reduce pain and improve pulmonary function in patients underwent to bariatric surgery.
- Trial name
- LILYBET (NCT07119437)
- Testing
- low pneumoperitoneum laparoscopy with microsurgery, standard laparoscopy
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Morbid Obesity
Cost Analysis of Bariatric Surgery in an Employee-based Healthcare System Following Surgery Coverage
The overall purpose of the study is to determine prospectively the cost effectiveness of bariatric surgery following partial coverage by a large healthcare system.
- Trial name
- NCT02381704
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- AdventHealth
Obesity, Morbid, Obesity; Endocrine
Impact of MBS on Body Composition, Basal Metabolic Rates and Muscle Functions in Morbid Obese Patients
PRIMARY OBJECTIVE To evaluate the changes in body composition in morbid obese patients following bariatric and metabolic surgery Secondary Objectives: 1. To assess changes in BMR in obese patients following bariatric surgery 2.
- Conditions
- Obesity, Morbid, Obesity; Endocrine, Fat Disorder
- Trial name
- BARCOM (NCT07737860)
- Volunteers
- 21 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Obesity, Bariatric Surgery
Effects of Caloric Restriction Alone Versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients With Diabetes Mellitus
Background: Bariatric surgery is the most effective way to achieve significant, long-term weight loss. It has also been shown to be an effective therapy for obese individuals with type 2 diabetes: more than 70 percent of patients…
- Conditions
- Obesity, Bariatric Surgery, Morbid Obesity, Diabetes Mellitus Type 2
- Trial name
- NCT01083108
- Testing
- Roux-en-Y Gastric Bypass, Caloric Restriction
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Morbid, Time Restricted Eating
Time-restricted Eating Among Pregnant Females With Severe Obesity
In the United States, a body mass index (BMI) of at least 35.0 kg/m2 affects about 15% of women of reproductive age. Severe obesity is a significant predictor of adverse perinatal outcomes including gestational diabetes mellitus…
- Conditions
- Obesity, Morbid, Time Restricted Eating, Pregnancy Weight Gain
- Trial name
- TRE-Preg (NCT06477120)
- Testing
- Time Restricted Eating
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Morbid Obesity, Respiratory Failure
Comparison of Esophageal Manometry and CT Scan Measurements
The goal of this study is to determine the relationship between esophageal pressure (Pes) and superimposed pressure (SP) in subjects with morbid obesity.
- Trial name
- NCT04213911
- Testing
- low-dose chest CT scan, insertion of esophageal balloon
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Bariatric Surgery Candidate, Obesity
Comparing 150cm OAGB With 150cm Biliopancreatic Limb RYGB. A Non-inferiority Trial
The purpose of this study is to assess the safety and efficiency of OAGB compared to RYGB
- Conditions
- Bariatric Surgery Candidate, Obesity, Obesity, Morbid
- Trial name
- Roux-en-WHY? (NCT04852198)
- Testing
- OAGB, RYGB
- Where
- 2 sites in Netherlands
- Volunteers
- 298 people
- Sponsor
- Flevoziekenhuis
Morbid Obesity
Surgical Conditions During Laparoscopic Bariatric Surgery
Obesity affects more than 78 million adults in the United States and it is estimated that 35% of the US population is obese. Currently, more than 179,000 bariatric procedures are performed in the US each year with the majority of…
- Trial name
- NCT02703909
- Testing
- Rocuronium, Insufflation pressure
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Missouri-Columbia
Obesity, Morbid Obesity
Patient Reported Outcomes of a "Tailored" Bilio-Pancreatic Limb Length on Daily Food Choices in Mini-Gastric Bypass
Bariatric surgery (BS) has a history of new procedures and techniques arising and then disappearing due to problems and complications.
- Conditions
- Obesity, Morbid Obesity, Bariatric Surgery Candidate, Food Selection
- Trial name
- TaBLFood-MGB (NCT04442139)
- Testing
- Mini-Gastric Bypass
- Where
- India
- Volunteers
- 190 people
- Sponsor
- Kular Hospital
Obesity
Long Term Follow up After 1 Year Initial Lifestyle Intervention
The effect of non-surgical methods for obesity treatment are not fully documented. This study focus on the long term effect of an intensiv follow up (the "Evje Model") compared to a regular follow up.
- Trial name
- NCT00477399
- Testing
- Long term follow up after intensive lifestyle intervention
- Where
- Norway
- Sponsor
- Tor-Ivar Karlsen
Morbid Obesity, Sleeve Gastrectomy
Safety of an Early Discharge Protocol After Sleeve Gastrectomy
Evaluate the safety and efficacy of an early discharge protocol (23 hours, overnight stay) after scheduled sleeve gastrectomy.
- Conditions
- Morbid Obesity, Sleeve Gastrectomy, Early Discharge, Safety Issues
- Trial name
- NCT03070457
- Testing
- Early discharge, Conventional protocol
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari de Bellvitge
Morbid Obesity
Laparoscopic Gastric Bypass vs LAP-BAND for Treatment of Morbid Obesity
PURPOSE Obesity is a growing problem in the United States. Severe obesity, known as "morbid obesity", is defined as being 100 pounds in excess of ideal body weight.
- Trial name
- NCT00247377
- Testing
- Gastric bypass surgery, Lap-Band
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- University of California, Irvine
Obesity
Gastric Bypass and Peripheral Activity of the Endocannabinoid System
The aim of the study is to precise the effect of a large amount of weight loss induced by gastric bypass on the endocannabinoid system (plasma and adipose tissue) of morbidly obese patients and to determine the influence of a…
- Trial name
- CCENDO (NCT01003873)
- Testing
- Evaluation of the endocannabinoid system, Biopsy of visceral and peripheral adipose tissue, Evaluation of metabolic parameters
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Obesity, Cardiovascular Diseases
A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease
The main purpose of this study is to evaluate the efficacy and safety of retatrutide once weekly in participants with obesity and established cardiovascular disease (CVD). The study will last about 113 weeks.
- Trial name
- TRIUMPH-3 (NCT05882045)
- Testing
- Retatrutide
- Where
- 169 sites in United States, Argentina and 8 more
- Volunteers
- 1,946 people
- Sponsor
- Eli Lilly and Company
Morbid Obesity
One Anastomosis Gastric Bypass for Severe Obesity in 6,722 Patients: Early Outcomes From the Assuta Surgery Registry
Background: One-anastomosis gastric bypass (OAGB) is an emerging type of bariatric metabolic surgery (BMS). Our study aimed to evaluate the short-term (≤30-day) postoperative safety of OAGB.
- Trial name
- NCT05481853
- Testing
- One Anastomosis Gastric Bypass
- Where
- Israel
- Volunteers
- 6,722 people
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Obesity, Morbid, Anal Incontinence
Impact of Bariatric Surgery in Patients With Morbid Obesity
The main objective is to compare the prevalence of anal incontinence (AI) before and after bariatric surgery in obese patients. Inclusion: Patients who are scheduled for a bariatric surgical procedure after a multidisciplinary…
- Conditions
- Obesity, Morbid, Anal Incontinence, Image, Body
- Trial name
- IVBIA (NCT04009356)
- Testing
- bariatric surgical procedures
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Calcium Metabolism Disorders, Morbid Obesity
Effects of Sleeve Gastrectomy on Calcium Metabolism and the Skeleton
In this pre-post observational study, the investigators will enroll and follow a cohort of about 50 adults undergoing sleeve gastrectomy surgery for weight loss.
- Trial name
- NCT02778490
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- San Francisco Veterans Affairs Medical Center
Obesity, Obesity, Morbid
Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy - Part 2
Rapid metabolic improvements seen with sleeve gastrectomy are likely a result of changes in gastric origin. The gastric mucosa is an endocrine organ that regulates satiation pathways and is a complex regulator of food intake as…
- Conditions
- Obesity, Obesity, Morbid, Obesity; Endocrine, Bariatric Surgery Candidate
- Trial name
- NCT03638843
- Testing
- Gastric mucosal devitalization
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Johns Hopkins University
Obesity, Morbid
Ambulatory Laparoscopic Sleeve Gastrectomy
In the era of laparoscopic surgery, day case procedures are increasingly practiced around the world, however, day case bariatric surgery remains a controversial issue due to lack of sufficient evidence evaluating its safety.
- Trial name
- DAYSLEEVE (NCT05106660)
- Testing
- Ambulatory Laparoscopic Sleeve Gastrectomy, Conventional Laparoscopic Sleeve Gastrectomy
- Where
- Saudi Arabia
- Volunteers
- 1,554 people
- Sponsor
- King Saud University
Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying
GLP_1 RA Ultrasound Study
The purpose of the study is to determine whether patients taking GLP-1 RAs have increased residual (left behind), gastric (stomach), contents due to delayed gastric emptying when following standard preoperative fasting guidelines.
- Conditions
- Glucagon Like Peptide-1 (GLP-1, Delayed Gastric Emptying, Risk of Aspiration, Diabetes
- Trial name
- NCT06581120
- Testing
- Glucagon-Like Peptide-1 receptor agonists, Point of Care Gastric Ultrasound
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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